KEGG   Orcinus orca (killer whale): 101279434
Entry
101279434         CDS       T05247                                 
Symbol
ABCB1
Name
(RefSeq) ATP-dependent translocase ABCB1
  KO
K05658  ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor02010  ABC transporters
oor04976  Bile secretion
oor05206  MicroRNAs in cancer
oor05226  Gastric cancer
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    101279434 (ABCB1)
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    101279434 (ABCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    101279434 (ABCB1)
  09162 Cancer: specific types
   05226 Gastric cancer
    101279434 (ABCB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:oor02000]
    101279434 (ABCB1)
   04147 Exosome [BR:oor04147]
    101279434 (ABCB1)
   04090 CD molecules [BR:oor04090]
    101279434 (ABCB1)
Enzymes [BR:oor01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     101279434 (ABCB1)
Transporters [BR:oor02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB1, 4, 5 subgroups
    101279434 (ABCB1)
Exosome [BR:oor04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   101279434 (ABCB1)
CD molecules [BR:oor04090]
 Proteins
  101279434 (ABCB1)
SSDB
Motif
Pfam: ABC_membrane ABC_tran SMC_N ABC_ATPase AAA_16 AAA_22 RsgA_GTPase Rad17 AAA Zeta_toxin AAA_5 AAA_14 AAA_29 SbcC_Walker_B G-alpha AAA_7 APS_kinase AAA_30 PRK DUF815 NTPase_1 AAA_15 DUF2207_C
Other DBs
NCBI-GeneID: 101279434
NCBI-ProteinID: XP_004263552
LinkDB
Position
9:75726860..75833139
AA seq 1284 aa
MDLEEGRSGSAGGENFLKKDKKRFFSKKDEKKEKKPTVSTFAVFRYSNWLDKLYMVLGTV
AAIIHGAGLPLTMLVFGDMTDSFANAGNLGNLTISQLTNGSFLDSTYFGEKLEEEMTTYA
YYYSGIGAGVLVAAYIQVSFWCLAAGRQVYKIRKQFFHAVMRQEVGWFDVHDTGELNTRL
SDDVSKINEGIGDKIGIFFQSMATFFTGFTVGFTQGWKLTLVILAVSPVLGLSAAIWAKI
LSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITA
NISMGAAFLLIYASYALAFWYGTSLVLSEDYSIGQVLTVFFSVLIGAFSVGQASPSIEAF
ANARGAAYEIFKIIDNKPSIDSYSKNGRKPDNIKGNLEFRNVHFNYPSRNEVKILKGLNL
KVESGQTVALVGNSGCGKSTTVQLIQRLYDPTEGVISIDGQDIRTINVRYLREIIGVVSQ
EPVLFATTIAENIRYGRENVTMDEIEKAVKEASAYDFIMKLPNKFDTLVGERGAQLSGGQ
KQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKAREGRTTIVIAHRLSTVRNA
DVIAGLDDGVTVEKGSHDELMKEKGIYFKLVTMQTKGNDIELENAAGGSESEIDALDMSP
KDLGSSLIRRKSTRKSIHGPQSQNRKLSTEETSDENVPPVSFWRILKLNITEWPYFVVGI
FCAIVNGGLQPAFSVIFSRIIGVFTRDDDPETKRQNSNLFSLLFLILGIISFITFFLQGY
TFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVQGAIGSRLAV
ITQNIANLGTGIVISLIYGWQLTLLLLAIVPIIAVAGVIEMKMLSGQALKDKKELEDAGK
IATEAIENFRTVVSLTREEKFEYMYALSLQVPYRNSLRKAHIFGITFSITQAMMYFSYAG
CFRFGAYLVAHGIIDFQDVLLVFSAIVFGAMAVGQVSSFAPDYAKAKVSAAHVIMIIEKA
PVIDSYSTEGLKPNTVEGNVTFNEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCG
KSTVVQLLERFYDPLAGTVLIDGKEIKHLNVQWLRAHMGIVSQEPVLFDCSIGENIAYGD
NSRVVSQEEIVQAAKEANIHPFVETLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPR
ILLLDEATSALDTESEKVVQEALDKAQEGRTCIVIAHRLSTIQNADLIVVFQNGKVKEHG
THQQLLAQKGIYFSMVSVQAGAKR
NT seq 3855 nt   +upstreamnt  +downstreamnt
atggatcttgaagaaggccgcagtggaagtgcagggggggagaacttcttgaaaaaggac
aagaaaaggtttttcagtaaaaaagatgagaagaaagaaaagaaaccaactgtcagtact
tttgcagtgtttcgctattcgaattggcttgataagttgtatatggtgttggggactgtg
gccgccatcatccacggagccggactccccctcacgatgctggtttttggagacatgacg
gatagctttgcaaatgcaggaaatttaggaaacctgactatttcacaactaactaatgga
agttttctggacagtacgtatttcggcgaaaagctggaggaggaaatgaccacgtacgcc
tattattacagtggaatcggggctggcgtgcttgttgccgcttacatccaggtttcattc
tggtgcctggcagcaggaagacaagtatacaaaattagaaaacagttttttcatgctgtc
atgcggcaggaggtaggctggtttgacgtgcatgacactggggagcttaacacccggctc
tcagatgacgtctccaaaattaatgaaggaattggtgacaaaattggaatattctttcag
tcaatggcaacattcttcaccggttttacagtaggatttacacaaggttggaagttaacc
cttgtgattttagccgtcagtcctgttcttggtctgtcagctgctatctgggcaaagata
ctatcttcatttactgataaagaactcttggcatatgcaaaagctggagcagtagctgaa
gaggtgttagcagcaattagaactgtgattgcatttggaggacaaaagaaagaacttgaa
aggtacaacaaaaatttggaagaagctaaaagaattggaataaagaaagctattacagcc
aacatctctatgggtgcagctttcctgttgatctatgcatcatatgctctggcattctgg
tatgggacctccttagtcctgtcagaagattattctattggacaagtactcactgtcttc
ttttccgtattaattggggcttttagtgttggacaggcatctccaagcattgaggcattt
gcaaatgcaagaggagcagcttatgaaatctttaagatcatcgataacaaaccaagcatc
gacagctattcgaagaatgggcgcaaacccgataatattaagggaaatctggaattcaga
aatgttcacttcaattacccatctcgaaacgaagttaagatcttgaagggcctcaacttg
aaggtagagagcgggcagacggtggcactggttggaaacagcggctgtgggaaaagcacg
acggtccagctgatacagaggctctatgaccccacagagggcgtgatcagtattgacgga
caggacatcaggaccatcaatgtaaggtatctgcgggaaattatcggtgtggtgagtcag
gaacctgtgttgtttgctaccaccatagccgagaacattcgctacggccgtgaaaatgta
accatggatgagattgagaaagctgtgaaggaagccagcgcctatgacttcatcatgaaa
ctgcctaataaatttgacaccctggttggagagagaggggcccagctgagtggtggacag
aagcagagaatcgccattgctcgggctctggttcgcaaccccaagatcctgctgctggat
gaggccacctcagcgctggacactgagagtgaagcggtggttcaggtggccctggataag
gccagagaaggccggaccaccatcgtgatcgcgcatcgtttgtccacagtgcgtaatgct
gatgtcattgctggtcttgatgatggagtcactgtggagaaaggcagtcatgatgaactc
atgaaggagaaaggcatttacttcaaacttgtcacaatgcagacaaaaggaaatgatatt
gaattagaaaatgcagctggtggatccgaaagtgaaattgatgccttggacatgtccccc
aaagatttaggatccagtctaataagaagaaaatcaactcgcaagagtatccatggacca
caaagccaaaacagaaagcttagtacagaagagacttcggatgaaaatgtacctccagtt
tctttttggaggattctgaagctgaatataactgaatggccttattttgtggttggtata
ttttgtgccattgtaaatggaggtctgcaaccagcattttcagtaatattttcaaggatt
ataggggtttttaccagagatgacgatcctgaaaccaaacgacagaatagtaacttgttt
tcactcttgtttctaatccttggaattatttcttttattacgtttttccttcagggctac
acgtttggcaaggccggagagatcctcaccaagcggctccgatacatggttttcagatcc
atgctgagacaggatgtgagctggtttgacgaccctaaaaacaccacgggagccttgacg
accaggctggccaatgatgctgctcaagttcaaggggctataggttccaggcttgctgta
attacccagaatatagcaaatcttgggacaggcattgttatatccttaatctatggctgg
cagttaacacttttactgttagcaattgtacccatcattgcagtagcaggagttattgaa
atgaaaatgctgtctggacaagcactgaaagataagaaagaactagaagatgccgggaag
attgccacggaagcaatagaaaacttccgaactgttgtttctttgactcgggaggagaag
tttgaatatatgtatgccctgagtttgcaggtaccatacagaaactctttgaggaaagca
cacatctttggaatcacgttttccatcacccaggcaatgatgtatttttcttacgctggc
tgtttccgttttggcgcctacctggtggcacatggcatcatagactttcaggatgttctc
ttagtgttctcagccattgtctttggcgcgatggctgtgggtcaggtcagttcatttgct
cctgactatgccaaggccaaagtgtcagcagcccacgtcatcatgatcattgaaaaagcc
cctgtgatcgacagctacagcacggaaggcctaaagccgaatacagtggaaggaaatgtg
acatttaatgaagtcgtgttcaactatcccactcgaccagacatcccagtgcttcagggg
ctgagcctcgaggtgaagaagggccagacgctggccctggtgggcagcagcggctgtggg
aaaagcacggtggtccagctcctggagcggttctacgaccccttggctggaacagtgcta
attgacggcaaggaaataaagcacctgaatgtccagtggctccgagcacacatgggcatc
gtgtcccaggagcccgtcctgtttgactgcagcatcggcgagaacatcgcctatggggac
aacagccgggtcgtgtcccaggaggagatcgtgcaggcagccaaggaggccaacatacac
cccttcgtcgagacgctgcctgataaatataacaccagagtaggagacaaaggaactcag
ctctctggtggccagaagcagcgcattgcgatagctcgtgcccttgttagacagcctcgt
atattgcttctggatgaagctacatcagctctggatacagaaagtgaaaaggttgtccaa
gaagccctggacaaagcccaagaagggcgcacctgcatcgtcatcgctcaccgcctgtcc
accattcagaatgcagacttgatagtggtgtttcagaacggcaaagtcaaggagcacggc
acacaccagcagctgctggcacagaaaggcatctatttctccatggtcagtgtccaggct
ggagcaaagcgctag

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