KEGG   Orcinus orca (killer whale): 101279623
Entry
101279623         CDS       T05247                                 
Symbol
FGFR1
Name
(RefSeq) fibroblast growth factor receptor 1 isoform X3
  KO
K04362  fibroblast growth factor receptor 1 [EC:2.7.10.1]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04010  MAPK signaling pathway
oor04014  Ras signaling pathway
oor04015  Rap1 signaling pathway
oor04020  Calcium signaling pathway
oor04151  PI3K-Akt signaling pathway
oor04520  Adherens junction
oor04550  Signaling pathways regulating pluripotency of stem cells
oor04714  Thermogenesis
oor04810  Regulation of actin cytoskeleton
oor04928  Parathyroid hormone synthesis, secretion and action
oor05200  Pathways in cancer
oor05205  Proteoglycans in cancer
oor05215  Prostate cancer
oor05218  Melanoma
oor05224  Breast cancer
oor05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101279623 (FGFR1)
   04014 Ras signaling pathway
    101279623 (FGFR1)
   04015 Rap1 signaling pathway
    101279623 (FGFR1)
   04020 Calcium signaling pathway
    101279623 (FGFR1)
   04151 PI3K-Akt signaling pathway
    101279623 (FGFR1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    101279623 (FGFR1)
   04550 Signaling pathways regulating pluripotency of stem cells
    101279623 (FGFR1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101279623 (FGFR1)
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    101279623 (FGFR1)
  09159 Environmental adaptation
   04714 Thermogenesis
    101279623 (FGFR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101279623 (FGFR1)
   05205 Proteoglycans in cancer
    101279623 (FGFR1)
   05230 Central carbon metabolism in cancer
    101279623 (FGFR1)
  09162 Cancer: specific types
   05218 Melanoma
    101279623 (FGFR1)
   05215 Prostate cancer
    101279623 (FGFR1)
   05224 Breast cancer
    101279623 (FGFR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:oor01001]
    101279623 (FGFR1)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:oor04090]
    101279623 (FGFR1)
   00536 Glycosaminoglycan binding proteins [BR:oor00536]
    101279623 (FGFR1)
Enzymes [BR:oor01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     101279623 (FGFR1)
Protein kinases [BR:oor01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   101279623 (FGFR1)
CD molecules [BR:oor04090]
 Proteins
  101279623 (FGFR1)
Glycosaminoglycan binding proteins [BR:oor00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   101279623 (FGFR1)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set ig Ig_3 Ig_2 V-set C2-set_2 Ig_4 ABC1 V-set_CD47 Pkinase_fungal DUF1615 zf-CCCH_9
Other DBs
NCBI-GeneID: 101279623
NCBI-ProteinID: XP_004284938
LinkDB
Position
21:5587999..5636066
AA seq 820 aa
MWSWKCLLFWAVLVTAALCTARPAPTLPEQAQPWGAPVEVESLLVHPGDLLQLRCRLRDD
VQSINWLRDGVQLVESNRTRITGEEVEVRDSVPADSGLYACVTSSPSGSDTTYFSVNVSD
ALPSSEDDDDDDDSSSEEKETDNTKPNRMPVAPYWTSPEKMEKKLHAVPAAKTVKFKCPS
SGTPNPTLRWLKNGKEFKPDHRIGGYKVRYATWSIIMDSVVPSDKGNYTCVVENEYGSIN
HTYQLDVVERSPHRPILQAGLPANKTVALGSNVEFMCKVYSDPQPHIQWLKHIEVNGSKI
GPDNLPYVQILKTAGVNTTDKEMEVLHLRNVSFEDAGEYTCLAGNSIGLSHHSAWLTVLE
ALEERPAVMTSPLYLEIIIYCTGAFLISCMVGSVIIYKMKSGTKKSDFHSQMAVHKLAKS
IPLRRQVSADSSASMNSGVLLVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGK
PLGEGCFGQVVLAEAIGLDKDKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHK
NIINLLGACTQDGPLYVIVEYASKGNLREYLQARRPPGLEYCYNPSRHPEEQLSSKDLVS
CAYQVARGMEYLASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRL
PVKWMAPEALFDRIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKP
SNCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLSMPLDQYSPSFPD
TRSSTCSSGEDSVFSHEPLPEEPCLPRHPAQLANGGLKRR
NT seq 2463 nt   +upstreamnt  +downstreamnt
atgtggagctggaagtgtctcctgttctgggctgtgctggtcacagccgcactctgcact
gccaggccagcgccaaccttgccggaacaagcccagccctggggagcccccgtggaagtg
gagtccctcctggtccaccccggtgacctgctgcagctccgctgtcggctgcgggacgat
gttcagagcatcaactggctgcgggacggggtgcagctggtggaaagcaaccgcacccgc
atcacgggggaggaggtggaggtgcgggattccgtgcccgccgactccggcctctacgcc
tgcgtgaccagcagcccctcgggcagcgataccacctacttctccgtcaacgtctcagat
gctctcccctcctcggaggacgatgatgacgatgatgactcctcttcagaggagaaagag
acagataacaccaaaccaaaccgtatgcccgtggctccctactggacgtcgccagaaaag
atggaaaagaaactgcacgcggtgccagctgccaagacagtgaagttcaaatgcccttcc
agtgggaccccgaaccccacactgcgctggctgaaaaatggcaaagaattcaagcctgac
cacaggatcggaggctacaaggtccgttatgccacctggagcatcataatggactccgtg
gtgccttctgataagggcaactacacctgcgtcgtggagaacgagtatggcagcatcaac
cacacctaccagcttgatgtcgtggagcggtcccctcaccggcccatcctgcaggcaggg
ttgccagccaacaagacagtggccctgggcagcaacgtggagttcatgtgtaaggtgtac
agcgacccgcagccccatatccagtggctaaagcacatcgaggtgaatgggagtaagatt
ggtccggacaacctgccttatgtccagatcttgaagacggccggagttaataccaccgac
aaagagatggaagtgctgcacttaaggaatgtctcctttgaggacgcgggggagtataca
tgcttggcgggtaactctatcggactctcccatcactctgcatggttgaccgttctggaa
gccctggaagagagaccggcggtgatgacctcgcccctgtacctggagatcatcatctat
tgcacgggggccttcctcatctcctgcatggtggggtccgtcatcatctataagatgaag
agtggcaccaagaagagtgacttccacagccagatggccgtgcacaagctggccaagagc
attcctctgcgcagacaggtgtcggccgactccagcgcatccatgaactcgggggtcctg
ctggtccggccctcgcgtctctcctccagcgggacccccatgctggctggggtctctgaa
tacgagcttcccgaagaccctcgctgggagctgcctcgggacagactggttttaggcaaa
cccctgggagagggctgctttgggcaggtggtgttggcggaggccattgggctggacaag
gacaaacccaaccgggtgaccaaagtggctgtgaagatgctgaagtcggatgcgaccgag
aaagacctgtcagacctgatctccgaaatggagatgatgaagatgatcgggaaacacaag
aacatcatcaacctgctgggggcctgcacgcaggacggccccctgtatgtcatcgtggag
tacgcctccaagggcaacctccgagagtacctgcaggcccggaggccgccggggctggaa
tactgctacaaccccagccgtcatcccgaggagcagctgtcctccaaggacctggtatcc
tgcgcctatcaggtggcccgaggcatggagtatctcgcctccaagaagtgcatacaccga
gacctggccgccaggaacgtgctggtgacggaggacaacgtgatgaagatcgcagacttt
ggcctagctcgtgacatccaccacatcgactactataaaaagacgaccaacggccgactg
cctgtcaagtggatggcacccgaggccttgttcgacaggatctacacccaccagagcgac
gtgtggtcttttggggtgcttctgtgggaaattttcactctgggcggctccccgtaccct
ggcgtccctgtggaggagcttttcaagctgctgaaggagggtcatcgtatggacaagccc
agtaactgcaccaatgagctgtacatgatgatgcgagactgctggcacgcggtaccctct
cagagacctaccttcaagcagctggtggaagacctggaccgcatagtggccttgacctcc
aaccaggagtacctggacctatcaatgcccctggaccagtactcccccagcttccccgac
acccgcagctctacctgctcctctggggaggattccgtcttctctcacgagcccttgccc
gaggagccctgtctgccccgacacccggcccagctggccaatggcggactcaaacggcgc
tga

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