Orcinus orca (killer whale): 101280638 Help Entry 101280638         CDS       T05247                                  Symbol NOS2 Name (RefSeq) nitric oxide synthase, inducible   KO K13241   nitric-oxide synthase, inducible [EC:1.14.13.39] Organism oor  Orcinus orca (killer whale) Pathway oor00220   Arginine biosynthesis oor00330   Arginine and proline metabolism oor01100   Metabolic pathways oor04020   Calcium signaling pathway oor04066   HIF-1 signaling pathway oor04146   Peroxisome oor04371   Apelin signaling pathway oor04926   Relaxin signaling pathway oor05010   Alzheimer disease oor05014   Amyotrophic lateral sclerosis oor05022   Pathways of neurodegeneration - multiple diseases oor05133   Pertussis oor05140   Leishmaniasis oor05142   Chagas disease oor05145   Toxoplasmosis oor05146   Amoebiasis oor05152   Tuberculosis oor05200   Pathways in cancer oor05222   Small cell lung cancer Brite KEGG Orthology (KO) [BR:oor00001]  09100 Metabolism   09105 Amino acid metabolism    00220 Arginine biosynthesis     101280638 (NOS2)    00330 Arginine and proline metabolism     101280638 (NOS2)  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     101280638 (NOS2)    04066 HIF-1 signaling pathway     101280638 (NOS2)    04020 Calcium signaling pathway     101280638 (NOS2)  09140 Cellular Processes   09141 Transport and catabolism    04146 Peroxisome     101280638 (NOS2)  09150 Organismal Systems   09152 Endocrine system    04926 Relaxin signaling pathway     101280638 (NOS2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101280638 (NOS2)   09162 Cancer: specific types    05222 Small cell lung cancer     101280638 (NOS2)   09171 Infectious disease: bacterial    05133 Pertussis     101280638 (NOS2)    05152 Tuberculosis     101280638 (NOS2)   09174 Infectious disease: parasitic    05146 Amoebiasis     101280638 (NOS2)    05145 Toxoplasmosis     101280638 (NOS2)    05140 Leishmaniasis     101280638 (NOS2)    05142 Chagas disease     101280638 (NOS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     101280638 (NOS2)    05014 Amyotrophic lateral sclerosis     101280638 (NOS2)    05022 Pathways of neurodegeneration - multiple diseases     101280638 (NOS2) Enzymes [BR:oor01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor     1.14.13.39  nitric-oxide synthase (NADPH)      101280638 (NOS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1 Motif Other DBs NCBI-GeneID:  101280638 NCBI-ProteinID:  XP_049558422 LinkDB All DBs Position 19:complement(4351756..4388407) Genome browser AA seq 1157 aa AA seqDB search MACPWQFLFKAKSYKFDLTEEMDINNNVDKAPVSFCSPVTQDDPKCHNLGKHRNESPQPL TGTAKQSPESLVKPAAPPSACPRHLRIKNWGSGMTFQDTLHHKAKGDLACKSRSCLGAIM NPKSLTIGPRDKPTLPDELLPQAIEFVNQYYGSFKEAKIEEHLARVEAVTKEIETTGTYQ LTGDELIFATKQAWRNAPRCIGRIQWSNLQVFDARSCSTAQEMFEHICRHLRYATNNGNI RSAITVFPQRSDGKHDFRVWNAQLIRYAGYQMPDGTIRGDPASVELTQLCIDLGWKPKYG RFDVVPLVLQADGRDPELFEIPPDLVFEVPMEHPKYEWFRELELKWYALPAVANMLLEVG GLEFPGCPFNGWYMGTEIGVRDFCDVQRYNILEEVGRRMGLETHKVASLWKDRAVIEINV AVLHSFQKHNVTIMDHHSAAESFMKYMQNEYRSRGGCPADWIWLVPPISGSITPVFHQEM LNYVLSPFYYYQVEAWKTHVWQDERRRPRRREIRFKVLVKAVLFASVLMREKMASRVRAT ILFATETGRSETLARDLGALFSCAFNPKVLCMDEYRLSHLEEEQLLLVVTSTFGNGDSPG NGEKLKKSLFMLKELTNKFRYAVFGLGSSMYPQFCAFAHDIDQKLSQLGASQIAPTGEGD ELSGQEEAFRGWAVQTFKAACETFDVRGKHHIQIPKLYTANVTWDLHHYRLVQDSQPLDL NKALGSMHAKHVFTMRLKSQRNLQSPKSSRTTLLVELSCEGSQGPSYLPGEHLGVFPGNQ PALVQGILERVVDGPAPHQPMRLETLCENGSYWVRDKRLPPCSLSQALTYFLDITTPPTQ LLLRKLAQLATDEAERQRLETLCQPSDYNKWKFTNSPTFLEVLEEFPSLRVSASFLLSQL PVLKPRYYSISSSRDHAPTEIHLTVAVLTYRTRDGQGPLHHGVCSTWLSNLKPQDPVPCF VRSASGFQLPEDPSHPCILIGPGTGIAPFRSFWQQRLHDAEHKGLQSGRMTLVFGCRRPD EDHLYREEMLEMTRKGVLHEVHTAYSRLPDQPKVYVQDILRQQLADEVLHVLHEDQGHLY VCGDVRAARDVARTLKQLVATALSLTEEQVEDYFFQLKNQKRYHEDIFGAVFPYEVKKDG AAGLPSNTRAPSAHRRS NT seq 3474 nt NT seq  +upstreamnt  +downstreamnt atggcctgtccctggcagtttctgttcaaggccaaatcctataagtttgatttgactgag gaaatggatatcaacaacaatgtagacaaagcccctgtttccttttgcagtccagtgaca caggatgaccccaaatgtcacaacctcggcaagcaccggaatgagtctccccagcccctc acggggacagcgaagcagtctccagaatccctggtcaagccggctgcacccccatcggcc tgcccacggcacctgaggatcaaaaactggggcagcgggatgactttccaagacacactt caccacaaggccaaaggggatctcgcttgcaagtccaggtcttgcctgggagccatcatg aaccccaaaagtttgaccataggacccagggacaagcctaccctcccagacgagcttcta cctcaagctattgaatttgtcaaccagtattatggctccttcaaagaggcaaaaatagag gaacatctggccagggtggaagcggtaacaaaggagatagaaacaacaggaacctaccag ctgacgggagatgagctcatcttcgccaccaagcaggcctggcgcaacgccccccgctgc attgggaggatccagtggtccaacctgcaggtcttcgacgcgcggagctgttccacggcc caggagatgttcgagcacatctgcagacacctgcgttatgccaccaacaacggcaacatc aggtcggccatcaccgtgttcccccagcggagcgacgggaaacatgacttccgggtctgg aacgcccagctcatccggtatgccggctaccagatgcctgatggtaccatcagaggagac cctgccagcgtggagctcacccagctgtgcatcgacctgggctggaagcccaagtacggc cgcttcgatgtggtgcctctggtcctgcaggctgatggccgtgaccctgagctcttcgaa atccctcccgaccttgtgtttgaggtgcccatggaacatcccaagtatgagtggttccgg gagctggagctgaagtggtatgccctgccggccgtagccaacatgctgcttgaggtgggt ggccttgagttcccagggtgccccttcaacggctggtatatgggcacagagatcggagtc cgggacttctgtgacgtccagcgctacaacatcctggaggaagtgggcaggagaatgggc ctggaaacacacaaggtggcctcactctggaaagaccgggctgtcattgagatcaatgtt gctgtgctccacagtttccagaagcataatgtgaccatcatggaccaccactcagctgca gagtccttcatgaagtacatgcagaatgagtaccggtcccgagggggttgcccagctgac tggatttggttggtccccccaatttctggaagcatcacccccgtgttccaccaggagatg ttaaattatgtcctgtcccctttctactactaccaggtggaggcctggaaaacccacgtc tggcaggatgagaggcggagaccccggagaagagagattcgattcaaagtcttggtcaaa gccgtgctctttgcgtcagtgctgatgcgtgagaagatggcttcccgggtcagagccacg atcctcttcgcaacagagacaggaagatcagaaacactggcccgggacctaggggccttg ttcagctgtgccttcaaccctaaggttctctgcatggacgaatacaggctgagccatctg gaggaggaacagctactgctggtggtgaccagcacgttcgggaacggagactcccctggc aacggagagaaactgaagaagtccctcttcatgctgaaagaactcaccaacaagttcagg tatgccgtgtttggcctcggctccagcatgtaccctcagttctgcgcctttgctcatgac atcgaccagaagttgtcccagctgggggcttctcagatcgccccaacaggggaaggggac gagctcagcgggcaggaggaggccttccgtggctgggccgtgcaaaccttcaaggcagcc tgtgagacgttcgatgtccgaggcaaacaccacatccagatccccaagctctacactgcc aatgtgacctgggacctgcaccactaccggctcgtgcaagactcacagcctttggacctc aacaaagccctcggcagtatgcacgccaagcatgtgttcaccatgaggctgaaatcgcag cggaatctacagagtccaaaatccagccgtaccaccctcctggtggaactctcctgtgag ggcagccaaggtccaagctacctgccgggagagcacctcggagttttcccaggcaaccag ccagccctggtccaaggcatcctggagcgagtggtggatggccctgccccccaccaaccc atgcgcctggagaccctctgcgagaacggcagctactgggtcagggacaagcgactgccc ccctgctcactcagccaggctctcacctatttcctggacatcaccaccccgccaacccag ctgctgctccgaaagcttgcccagctggccacggacgaggctgagaggcagaggctggag accctgtgccagccgtctgattacaacaagtggaagttcaccaatagccccaccttcctg gaggtgctggaggagttcccgtccctgcgggtgtccgccagcttcctgctctcccagctg cctgtcctgaagccccggtattactccatcagctcctccagggaccacgcacccacggag atccacctcaccgtggccgtgctcacgtaccgcacccgagacggccagggtcccctacac cacggcgtctgcagcacatggctcagcaacctgaagccccaagacccggtgccctgcttt gtgcgaagtgccagcggcttccagctccccgaggacccctcccacccttgcatcctcatc gggcctggcacgggcatcgcccccttccgcagcttctggcagcagcggcttcatgatgcc gagcacaaaggtctccagagcggccgcatgaccctggtgtttgggtgccgccgcccagat gaggaccacctctaccgggaagagatgttggagatgacccggaagggggtgctgcatgag gtgcacacagcctattctcgcctgcctgaccagcccaaggtctacgttcaagacatcctg cggcaacagctggcggacgaggtgctgcacgtgctccacgaggaccagggccacctctac gtctgcggggacgtgcgcgcagcccgggatgtggcccgcaccctgaagcagctggtggcc accgcgctgagcctaactgaggagcaggtggaggactatttcttccagcttaagaaccag aagcgctatcatgaagatatctttggtgctgtatttccctatgaggtgaaaaaggatggg gcagcggggctgcccagcaataccagagctccaagcgcccacaggagaagttaa

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