Orcinus orca (killer whale): 101281473
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Entry
101281473 CDS
T05247
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00260
Glycine, serine and threonine metabolism
oor00630
Glyoxylate and dicarboxylate metabolism
oor00670
One carbon pool by folate
oor01100
Metabolic pathways
oor01200
Carbon metabolism
oor01230
Biosynthesis of amino acids
oor01240
Biosynthesis of cofactors
oor01523
Antifolate resistance
oor04981
Folate transport and metabolism
Module
oor_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
101281473 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
101281473 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101281473 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
101281473 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101281473 (SHMT1)
Enzymes [BR:
oor01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
101281473 (SHMT1)
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Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
101281473
NCBI-ProteinID:
XP_033278610
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All DBs
Position
19:19504061..19540355
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AA seq
484 aa
AA seq
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MATPVNGAPVDANLWSSHEKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELEVLCQKRALQVYGLDPQGWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTNKKKISATSIFFESMPYKVNPDTGY
INYDQLEENARLFHPKLIIAGTSCYSRNLDYARLREIADDNGAYLMADMAHISGLVAAGV
VPSPFEHCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGRETRYNLESLINSAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFRLYQRQVLANCRALAETLMALGYKVVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQK
VAHFIHRGIELTLQIQDTVGVKATLKEFTEKLAGAEDHQRAVAALRAEVESFAALFPLPG
LPDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgactcccgtcaacggagcccccgtggatgccaacttgtggtcctcgcatgagaag
atgctggcgcagcccctgaaagatagcgacgtggaggtttacaacatcattaagaaggag
agtaaccggcagagggtcggcctggagctgatcgcctccgagaactttgccagccgggct
gttctggaggccctgggttcttgcctaaacaacaagtactccgaggggtacccgggccaa
aggtactacggcgggacggaattcatcgatgagctggaggtcctctgtcagaagcgagcg
ctgcaggtctatggcctggacccccagggctggggagtcaatgtccaaccctactcaggc
tcccccgcaaacttcgcggtgtacacagccctggtggagccccacggccgcatcatgggc
ctggacctgcccgacgggggccacctgacccatgggttcatgaccaacaagaagaagatc
tctgctacgtccatcttttttgaatctatgccctacaaggtgaaccccgacaccggctac
atcaactacgaccagctggaggagaatgcccgcctcttccacccgaagctcatcatcgca
gggaccagctgctactcccggaacctggactacgcccggctgcgtgagatcgctgacgac
aacggggcgtatctcatggctgacatggcacacatcagtgggctggtggcggccggcgtg
gtgccctcccccttcgagcactgccacgtggtgtccaccaccacccacaagaccctgcgg
ggctgccgcgccggcatgatcttctacaggaagggagtgcgcagcgtggacccgaagacg
ggcagagagactcgctacaacctggagtcactcatcaactctgctgtgttcccaggcctg
caggggggcccccacaaccacgccattgctggggtggcggtggctctgaagcaggccatg
actccggagttcagactctaccagcgccaggtgctggccaactgcagggctctggccgag
accttgatggcgctgggctacaaagtggtcacaggtggttctgacaaccacttgatcctc
gtggacctccgctccaaaggcacagacggcggccgggctgagaaggtgctggaagcctgt
tccatcgcctgcaacaagaacacctgcccaggtgacaaaagcgccctgcggcccagcgga
ctgcgcctggggaccccggcgctgacatcccgaggactcttggaagaagatttccaaaaa
gttgcccattttattcacagagggatagagctgaccctgcagatccaggacaccgtgggg
gtgaaggctaccctgaaggagttcacggagaagctggcaggggccgaggatcaccagcgg
gctgtggcggcactcagggcggaggtggagagcttcgctgccctcttccctctgcccggc
ctgcccgacttctag
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