Orcinus orca (killer whale): 101281654 Help Entry 101281654         CDS       T05247                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism oor  Orcinus orca (killer whale) Pathway oor00230   Purine metabolism oor01100   Metabolic pathways oor01522   Endocrine resistance oor04015   Rap1 signaling pathway oor04020   Calcium signaling pathway oor04022   cGMP-PKG signaling pathway oor04024   cAMP signaling pathway oor04062   Chemokine signaling pathway oor04072   Phospholipase D signaling pathway oor04081   Hormone signaling oor04082   Neuroactive ligand signaling oor04114   Oocyte meiosis oor04211   Longevity regulating pathway oor04213   Longevity regulating pathway - multiple species oor04261   Adrenergic signaling in cardiomyocytes oor04270   Vascular smooth muscle contraction oor04371   Apelin signaling pathway oor04540   Gap junction oor04611   Platelet activation oor04713   Circadian entrainment oor04714   Thermogenesis oor04723   Retrograde endocannabinoid signaling oor04724   Glutamatergic synapse oor04725   Cholinergic synapse oor04727   GABAergic synapse oor04750   Inflammatory mediator regulation of TRP channels oor04911   Insulin secretion oor04912   GnRH signaling pathway oor04913   Ovarian steroidogenesis oor04914   Progesterone-mediated oocyte maturation oor04915   Estrogen signaling pathway oor04916   Melanogenesis oor04918   Thyroid hormone synthesis oor04921   Oxytocin signaling pathway oor04923   Regulation of lipolysis in adipocytes oor04925   Aldosterone synthesis and secretion oor04926   Relaxin signaling pathway oor04927   Cortisol synthesis and secretion oor04928   Parathyroid hormone synthesis, secretion and action oor04934   Cushing syndrome oor04935   Growth hormone synthesis, secretion and action oor04961   Endocrine and other factor-regulated calcium reabsorption oor04962   Vasopressin-regulated water reabsorption oor04970   Salivary secretion oor04971   Gastric acid secretion oor04972   Pancreatic secretion oor04976   Bile secretion oor05032   Morphine addiction oor05163   Human cytomegalovirus infection oor05166   Human T-cell leukemia virus 1 infection oor05200   Pathways in cancer oor05207   Chemical carcinogenesis - receptor activation oor05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:oor00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     101281654 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     101281654 (ADCY9)    04371 Apelin signaling pathway     101281654 (ADCY9)    04020 Calcium signaling pathway     101281654 (ADCY9)    04072 Phospholipase D signaling pathway     101281654 (ADCY9)    04024 cAMP signaling pathway     101281654 (ADCY9)    04022 cGMP-PKG signaling pathway     101281654 (ADCY9)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     101281654 (ADCY9)    04081 Hormone signaling     101281654 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     101281654 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     101281654 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     101281654 (ADCY9)    04062 Chemokine signaling pathway     101281654 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     101281654 (ADCY9)    04923 Regulation of lipolysis in adipocytes     101281654 (ADCY9)    04912 GnRH signaling pathway     101281654 (ADCY9)    04913 Ovarian steroidogenesis     101281654 (ADCY9)    04915 Estrogen signaling pathway     101281654 (ADCY9)    04914 Progesterone-mediated oocyte maturation     101281654 (ADCY9)    04921 Oxytocin signaling pathway     101281654 (ADCY9)    04926 Relaxin signaling pathway     101281654 (ADCY9)    04935 Growth hormone synthesis, secretion and action     101281654 (ADCY9)    04918 Thyroid hormone synthesis     101281654 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     101281654 (ADCY9)    04916 Melanogenesis     101281654 (ADCY9)    04925 Aldosterone synthesis and secretion     101281654 (ADCY9)    04927 Cortisol synthesis and secretion     101281654 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     101281654 (ADCY9)    04270 Vascular smooth muscle contraction     101281654 (ADCY9)   09154 Digestive system    04970 Salivary secretion     101281654 (ADCY9)    04971 Gastric acid secretion     101281654 (ADCY9)    04972 Pancreatic secretion     101281654 (ADCY9)    04976 Bile secretion     101281654 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     101281654 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     101281654 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     101281654 (ADCY9)    04727 GABAergic synapse     101281654 (ADCY9)    04725 Cholinergic synapse     101281654 (ADCY9)    04723 Retrograde endocannabinoid signaling     101281654 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     101281654 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     101281654 (ADCY9)    04213 Longevity regulating pathway - multiple species     101281654 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     101281654 (ADCY9)    04714 Thermogenesis     101281654 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     101281654 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     101281654 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     101281654 (ADCY9)    05163 Human cytomegalovirus infection     101281654 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     101281654 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     101281654 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     101281654 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     101281654 (ADCY9) Enzymes [BR:oor01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      101281654 (ADCY9) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom AC_N Motif Other DBs NCBI-GeneID:  101281654 NCBI-ProteinID:  XP_004270284 LinkDB All DBs Position 16:complement(52740186..52929452) Genome browser AA seq 1353 aa AA seqDB search MASPPHQQLLQHHSTEVSCDSSGDSNSVRVKINPKQLSSNSHPKHCKYSISSSCSSSGDS GGFPRRMGAGGRLRRKKKLPQLFERASSRWWDPKFDSMNLEEACMERCFPQTQRRFRYAL FYIGFACLLWSIYFGVHMRSKLTVMVAPALCFLVVCVGFFLFTFTKLYARHYVWTSLVLT LLVFALTLASQFQVLTPFSGRVDSFNHTRAARPTDTCLSQVGSFSMCIEVLFLLYTVMHL PLYLSLILGVAYSVLFETFGYHFQDKGCFPSPGAEALHWELLSRALLHVCIHAIGIHLFI MSQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKR HATSSPKNRKKKSSIQKAPIAFRPFKMQQIEEVSILFADIVGFTKMSANKSAHALVGLLN DLFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEK KEMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLD DRYEMEDGKVTERLGQNVVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVIDGSRVS SGPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCRIMFAPKLEAGAEGGAVQNGCQEEPKK STKASGGPSSKTQNGLLSPPPEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNI REKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLDQELEQAYRTSYQEEVIKNSPVKTF ASATFSSLLDVFLSTTVFLILSITCFLKYGAASMPPPPAALVVFGAALLLEILSLVVSVR MVFFLEDVMACTKRLLEWIAGWLPRHFIGAILVSLPALAVYSHVTSEFETNIHSTVFTGS AVLITVVHYCNFCQLSSWMRSSLATVVGAGPLLLLYVSLCPDSSIVISHLDAVQNFSSKR NPCNASLPHDSRSPASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTK IQSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDNGGVIFASIVNFSEFYEENYEGGKE CYRVLNELIGDFDELLSKPDYSSIEKIKTIGATYMAASGLNATQCRDGSHPQEHLQILFE FAKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTT GVECRIQVSEESYRVLSKMGYDFDYRGTVNVKGKGQMKTYLYPKCTDNGMVPQHQLSISP DIRVQVDGSIGRSPTDEITNLVPSVQNPDQVSLGSENNTQARDTHPSSKKPWKEPIKAEE RCRFSKAIEKSDCEEAGVEEANELTKLNVSKRA NT seq 4062 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccaacagctgctgcagcaccacagcaccgaggtgagttgtgac tccagcggagacagcaacagcgtgagggtcaaaatcaaccccaagcagctgtcctccaac agccacccgaaacactgcaagtacagcatctcctccagctgtagcagctccggggactca gggggcttcccccggagaatgggcgccggaggccgcctgcgcaggaaaaagaagctgcct cagctgttcgagagggcctccagccggtggtgggaccccaaattcgactccatgaacctg gaggaggcttgcatggagcgctgcttcccgcagacccagcgccgcttccggtatgcgctc ttctacattggcttcgcctgccttctctggagcatctattttggggtccacatgagatcc aaactgactgtcatggtagcccctgctctgtgcttcctcgtggtgtgtgtgggctttttt ctgtttaccttcaccaagctgtacgcccggcattacgtgtggacctcgctggttcttacc ctcctggtgttcgccctgactctggcttcccagtttcaggttttgacgcccttctcagga cgagttgacagcttcaatcatactcgggcagccaggcccacagacacttgcttatctcaa gtggggagcttttccatgtgcattgaagtgctctttttgctctacaccgtcatgcactta cctttgtacttgagcttgattttgggagtggcctattctgttctttttgagacctttggc tatcatttccaagacaaaggctgcttcccctcacctggagcagaggccctgcactgggag ctgctgagccgagccctgctgcatgtctgcattcacgccattgggatccacctgttcatc atgtcccaggtgagatccaggagcaccttcctcaaggtgggccagtcaattatgcatgga aaggatctggaagtggaaaaagcgctgaaagagaggatgattcattctgtgatgccaaga atcatagctgatgacttgatgaagcagggggacgaggagagcgagaattctgtcaaaagg catgccacctccagccccaagaacaggaagaaaaagtcttccatacagaaagcccctatt gccttccgcccattcaaaatgcagcagatcgaagaagtcagtattttattcgcagatatt gtgggcttcaccaagatgagtgccaataagtccgcccatgccctggtggggctcctcaat gatctgttcggccgcttcgaccggttgtgcgaggagaccaagtgtgagaaaatcagcact ctgggagactgctactattgtgtggccgggtgtcccgagcctcgggccgaccatgcctac tgctgcattgaaatgggcttgggcatgataagggctatcgagcagttctgccaagagaag aaagagatggtgaacatgcgcgttggggttcacacggggactgtcttgtgcggcatcttg ggcatgaggaggtttaaattcgacgtgtggtccaatgatgtgaacttggccaatctcatg gagcagctgggagtggctggcaaggttcacatttccgaggccactgcaaaatacctagat gaccggtacgaaatggaagatgggaaggttactgaacgcctcggccagaacgttgttgct gaccagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcat tgcagctgttcagaggccttgctttctggctttgaggtcattgacggctcacgggtgtcc tcaggccctaggggacaggggacagcatcgccagggagtgtcagtgacttggcgcagact gtcaaaacctttgataaccttaagacctgcccgtcgtgcagaatcatgtttgctcccaaa ttggaagctggcgctgaaggcggagcagtccagaatggctgccaggaggagcccaagaag agcaccaaggcttctggaggacccagttccaaaacgcaaaacggactgctaagccctccc ccggaggagaagctcaccaacagtcagacctccctgtgcgagatcttacaagagaaggga aggtgggcaggtgtgagcttggaccagtcagccctccttcctctgaggttcaagaacatc cgggagaaaacggatgcccattttgttgacgttatcaaggaagacagcctgatgaaagat tatttttttaagccacccattaatcagttcagcttgaacttcctggatcaggagctagaa caagcctacaggaccagctatcaagaagaggttataaagaattctcccgtgaagactttt gccagtgccaccttcagctccctcctggatgtgtttctgtcgacaacagtgtttctgatt ctctccattacctgcttcctgaagtatggggccgcctccatgccacccccgccggccgcc ctggtggtcttcggagcagccctgcttctggagatcctgtccctcgtggtctctgtcagg atggtgttcttcctggaggatgtgatggcttgtaccaagcgcctgctggagtggatagcc ggctggctcccgcgccatttcatcggggccatcctggtgtccctccccgccctcgcagtc tattcacatgtcacctccgaatttgagacaaacatacactccaccgtgttcacgggctcg gctgtcctgatcaccgtggtgcactactgtaacttctgccagctcagctcctggatgagg tcctccttggccacagtcgtcggggccgggcccctgctgctgctctacgtctccctctgc ccagacagttccatagtaatttcacacctggatgcagtacagaatttcagctccaagagg aatccgtgcaacgcctcgctgccgcacgacagcaggagcccagccagcctgatcggccag gaggtgattcttgtcttcttcctcctgctcttgttggtctggttcctgaatcgagaattc gaagtcagctaccgcctacactaccacggggacgtggaggcggacctgcaccgcactaag atccagagcatgagggaccaggccgactggctgctgagaaacatcatcccctaccacgtg gccgagcagctgaaggtctcccagacctactcgaagaaccacgacaacggaggagtcatc ttcgccagcatcgtcaacttcagcgagttctatgaggagaactacgagggcggcaaggag tgctaccgggtcctcaacgagctgatcggggacttcgacgagctcctgagcaagccggac tacagcagcattgagaagatcaagaccatcggggccacatacatggccgcgtcggggctg aacgccacacagtgccgtgacggcagccacccgcaggagcacctgcagatcctgtttgag ttcgccaaggaaatgatgcgcgtggtggacgacttcaacaataacatgctctggttcaac ttcaagctcagggtgggcttcaaccatgggcccctgacggcaggcgtcattggcaccacc aagctgctgtacgacatctggggagacacggtcaacatcgccagcaggatggacaccacg ggggtggagtgccgcatccaggtcagcgaggaaagctaccgcgtcctgagcaagatgggc tacgacttcgactacagagggacggtgaacgtcaagggcaaaggccagatgaagacctac ctgtaccccaagtgcacagacaacgggatggtgccgcagcaccagctctccatctccccc gacatccgagtccaggtggacggcagcatcggacgctcccccacggacgagatcaccaac ctggtgccttctgtacagaacccggaccaggtgtccctgggctccgagaacaacacacag gccagggacactcacccgtcttctaagaaaccctggaaggagcccatcaaagccgaagaa aggtgtaggttcagcaaagccatagagaaaagcgactgtgaagaagcaggggtggaggaa gccaatgaactcaccaagctcaacgtctcaaagagggcatga

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