Orcinus orca (killer whale): 101282403
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Entry
101282403 CDS
T05247
Symbol
BACE1
Name
(RefSeq) beta-secretase 1
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101282403 (BACE1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
oor01002
]
101282403 (BACE1)
Enzymes [BR:
oor01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
101282403 (BACE1)
Peptidases and inhibitors [BR:
oor01002
]
Aspartic peptidases
Family A1: pepsin family
101282403 (BACE1)
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Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
PE-PGRS_C
Motif
Other DBs
NCBI-GeneID:
101282403
NCBI-ProteinID:
XP_004273403
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All DBs
Position
8:complement(94078212..94102200)
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AA seq
498 aa
AA seq
DB search
MAQALPWLLLWMGSGVLPAHGSQPGIRLPLRSGLGVAPLGLRLPRETDEEPSRRGSFVEM
VDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRD
LRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLA
YAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHS
LYMGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFE
AAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRITILP
QQYLRPVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVH
DEFRTAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCL
RCLRHQHDDFADDISLLK
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atggcccaagcgctgccctggctcctgctgtggatgggctctggggtgctgcctgcccac
ggctcccagcctggcatccggctgcccctgcgaagcgggctgggggtcgcccccctgggg
ctgcggctgccccgggagaccgacgaggagcccagccggaggggcagctttgtggagatg
gtggacaacctgaggggcaagtccggtcagggctactacgtggagatgaccgtgggcagc
cccccacagacgctcaacatcctggtggacacaggcagcagtaacttcgcagttggggcc
gccccccaccctttcctgcaccgctactaccagaggcagctgtccagtacataccgggac
ctccggaagggcgtgtatgtgccctacacccagggcaagtgggagggggagctgggcacc
gacctggtgagcatcccccacggccccaacgtcaccgttcgtgccaacatcgctgccatc
actgaatcagacaagttcttcatcaatggctccaactgggagggcatcctggggctggcc
tacgctgagatcgccaggcctgacgactccctggagccattctttgactcgttggtaaag
cagacccacgtgcccaatctcttctccctgcagctctgtggtgctggcttccccctcaac
cagtcggaggtgctggcctcagttggagggagcatgatcatcgggggtatcgaccactcg
ctgtacatgggcagcctctggtacacacccatccggcgggaatggtattacgaggtgatc
attgtgcgggtggagatcaatggacaggatctgaaaatggactgcaaggagtacaactat
gacaagagcatcgttgacagtggcaccaccaaccttcgtctgcccaagaaagtgtttgaa
gctgctgtcaaatccatcaaggcagcctcctcgacggagaagttcccagacggtttctgg
ctcggggagcagctggtgtgctggcaagcaggcaccaccccgtggaacattttcccggtc
atctcactctacctaatgggtgaggtcaccaatcagtccttccgaatcaccatccttcca
cagcaatacctgcggccagtggaagatgtggccacatcccaagacgactgttacaagttc
gccatctcacagtcatccacgggcactgtcatgggagccgttatcatggagggcttctac
gttgtctttgatcgggcccggaaacgaattggctttgctgtcagtgcttgccatgtgcac
gatgagttcaggacagcagcggtagaaggtccttttgtcaccctggacatggaagactgt
ggctacaacatcccacagacagatgaatcgaccctcatgaccatagcctatgtcatggct
gccatctgcgccctcttcatgctgcccctctgcctcatggtgtgtcagtggcgctgcctc
cgctgcctgcgccatcagcacgatgactttgctgatgacatctccctgctgaagtga
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