KEGG   Orcinus orca (killer whale): 101283651
Entry
101283651         CDS       T05247                                 
Symbol
ADCY3
Name
(RefSeq) adenylate cyclase type 3 isoform X1
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00230  Purine metabolism
oor01100  Metabolic pathways
oor01522  Endocrine resistance
oor04015  Rap1 signaling pathway
oor04020  Calcium signaling pathway
oor04022  cGMP-PKG signaling pathway
oor04024  cAMP signaling pathway
oor04062  Chemokine signaling pathway
oor04072  Phospholipase D signaling pathway
oor04081  Hormone signaling
oor04082  Neuroactive ligand signaling
oor04114  Oocyte meiosis
oor04211  Longevity regulating pathway
oor04213  Longevity regulating pathway - multiple species
oor04261  Adrenergic signaling in cardiomyocytes
oor04270  Vascular smooth muscle contraction
oor04371  Apelin signaling pathway
oor04540  Gap junction
oor04611  Platelet activation
oor04713  Circadian entrainment
oor04714  Thermogenesis
oor04723  Retrograde endocannabinoid signaling
oor04724  Glutamatergic synapse
oor04725  Cholinergic synapse
oor04727  GABAergic synapse
oor04740  Olfactory transduction
oor04750  Inflammatory mediator regulation of TRP channels
oor04911  Insulin secretion
oor04912  GnRH signaling pathway
oor04913  Ovarian steroidogenesis
oor04914  Progesterone-mediated oocyte maturation
oor04915  Estrogen signaling pathway
oor04916  Melanogenesis
oor04918  Thyroid hormone synthesis
oor04921  Oxytocin signaling pathway
oor04923  Regulation of lipolysis in adipocytes
oor04925  Aldosterone synthesis and secretion
oor04926  Relaxin signaling pathway
oor04927  Cortisol synthesis and secretion
oor04928  Parathyroid hormone synthesis, secretion and action
oor04934  Cushing syndrome
oor04935  Growth hormone synthesis, secretion and action
oor04962  Vasopressin-regulated water reabsorption
oor04970  Salivary secretion
oor04971  Gastric acid secretion
oor04972  Pancreatic secretion
oor04976  Bile secretion
oor05032  Morphine addiction
oor05163  Human cytomegalovirus infection
oor05166  Human T-cell leukemia virus 1 infection
oor05200  Pathways in cancer
oor05207  Chemical carcinogenesis - receptor activation
oor05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    101283651 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    101283651 (ADCY3)
   04371 Apelin signaling pathway
    101283651 (ADCY3)
   04020 Calcium signaling pathway
    101283651 (ADCY3)
   04072 Phospholipase D signaling pathway
    101283651 (ADCY3)
   04024 cAMP signaling pathway
    101283651 (ADCY3)
   04022 cGMP-PKG signaling pathway
    101283651 (ADCY3)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    101283651 (ADCY3)
   04081 Hormone signaling
    101283651 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101283651 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101283651 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    101283651 (ADCY3)
   04062 Chemokine signaling pathway
    101283651 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    101283651 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    101283651 (ADCY3)
   04912 GnRH signaling pathway
    101283651 (ADCY3)
   04913 Ovarian steroidogenesis
    101283651 (ADCY3)
   04915 Estrogen signaling pathway
    101283651 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    101283651 (ADCY3)
   04921 Oxytocin signaling pathway
    101283651 (ADCY3)
   04926 Relaxin signaling pathway
    101283651 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    101283651 (ADCY3)
   04918 Thyroid hormone synthesis
    101283651 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    101283651 (ADCY3)
   04916 Melanogenesis
    101283651 (ADCY3)
   04925 Aldosterone synthesis and secretion
    101283651 (ADCY3)
   04927 Cortisol synthesis and secretion
    101283651 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    101283651 (ADCY3)
   04270 Vascular smooth muscle contraction
    101283651 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    101283651 (ADCY3)
   04971 Gastric acid secretion
    101283651 (ADCY3)
   04972 Pancreatic secretion
    101283651 (ADCY3)
   04976 Bile secretion
    101283651 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    101283651 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    101283651 (ADCY3)
   04727 GABAergic synapse
    101283651 (ADCY3)
   04725 Cholinergic synapse
    101283651 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    101283651 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    101283651 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    101283651 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    101283651 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    101283651 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    101283651 (ADCY3)
   04714 Thermogenesis
    101283651 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101283651 (ADCY3)
   05207 Chemical carcinogenesis - receptor activation
    101283651 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101283651 (ADCY3)
   05163 Human cytomegalovirus infection
    101283651 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    101283651 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    101283651 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    101283651 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    101283651 (ADCY3)
Enzymes [BR:oor01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     101283651 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA Peptidase_S49_N
Other DBs
NCBI-GeneID: 101283651
NCBI-ProteinID: XP_033280939
LinkDB
Position
13:72536264..72618728
AA seq 1169 aa
MPRTQGFSDPEYSAEYSAEYSVSLPSDPDRRVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLAVAGVGLVLDII
LFVLCKKGLLPNRVTRKVVPYLLWLLITAQVFSYLGLNFSRAHAASDTVGWQAFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQRDGLKGMQLLREILANVFLYLCAIVVG
IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAADFRP
PLRPLLSLPLTPPCRGGTQDLPFQKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGL
AMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPG
RVHISQSTMDCLKGEFDVEPGDGGSRCDYLDEKGIETYLIIASKPEVKRTAAQNGLSGSA
LLNGAPPSSKPGSPALIETKEPNGSIHTSGSTSEEPDAQADNPSFPNPRRRLRLQDLADR
VVDASEDEHELNQLLNEALLERESAQVVKKRNTFFLSMRFMDREMETRYSVEKEKQSGAA
FSCSCVVLLCTALVEILIDPWLMTNYVTFVVGEVLLLTLTVCSLAAIFPRAFPKKIVAFS
TWIDRTRWARNTWAMLAIFILVMANVVDMLSCLQYYMGPTNGTSRVQIEDGCVENPKYYN
YVAVLSLIATIMLVQVSHMVKLTLMLLIAGAVAVINIYAWRPIFDEYDRRRFQEHDFPMV
ALEKMQVLSSPGLNGTDRLPLVPSKCSMTVMIFVMMLSFYYFSRHVEKLARTLFLWKIEV
HDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFAD
FYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTN
GFTSSNKERSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIG
ARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELL
TFFLKGREKPATFPNGSSVTLPHQVVDNS
NT seq 3510 nt   +upstreamnt  +downstreamnt
atgccgaggacccagggcttctccgatcctgagtactcggccgagtactcagccgagtac
tccgtcagcctgccctctgaccctgaccgcagggtgggccggacccatgagatctctgtc
cggaactcgggatcctgcctgtgcctgcctcgcttcatgcggctgaccttcgtgccggag
tccttggagaacctgtaccagacctacttcaaaaggcagcgccacgagacgctgctggtg
ctggtggtgttcgcggccctcttcgactgctacgtggtggtcatgtgcgcggtggtcttc
tccagtgacaagctggctcccctggctgtggccggggtggggctggtgttggacatcatc
ctgtttgtgctctgcaaaaaggggctgctgcccaaccgggtcacccggaaagtggtgccc
tacctgctgtggctgctgataacagcccaggtcttctcgtacctgggcctgaacttctcc
cgcgcccatgcagccagcgacacggtgggctggcaggccttcttcgtcttctccttcttt
atcacgctgcccctcagcctcagccccatcgtcatcatctctgtggtctcctgcgtcgtg
cacacgctcgtcttgggggtcaccgtggcccagcagcagcgggacgggctgaaggggatg
cagttgctgagggagattctggccaatgtcttcctctacctgtgcgccatcgttgtgggc
atcatgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgccag
tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctt
tccatcctgcccaagcacgtggcagacgagatgctgaaggacatgaagaaggacgagagc
cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaatgtcagcatc
ctctttgccgacatcgtgggcttcacccagctgtcttcagcctgcagcgcccaggagctc
gtgaagctcctcaacgagctcttcgcccgcttcgacaagctggcggccgacttccgccca
cccctccgtcctctgctttctttgcccctcacccccccttgccgaggagggactcaggac
ctgccctttcagaaataccaccagctgcggattaagattctgggcgactgttactactgc
atctgtgggctgcctgactaccgggaggaccacgccgtctgctccatcctcatggggctc
gccatggtggaggccatctcgtatgtacgggagaagacgaagactggggtggacatgcga
gtcggggtgcacacaggcactgtgctggggggtgtcctgggccagaagcgctggcagtac
gacgtgtggtccaccgacgtcactgtggccaacaagatggaggccggcggcatccccggg
cgtgtgcacatctcccagagcaccatggactgcctgaaaggcgagttcgacgtggagcca
ggcgatgggggcagccgctgtgattacctggatgagaagggcatcgaaacctacctcatc
attgcgtccaagccagaggtgaagaggacagctgcccaaaatggcctcagcggctcggct
ctgctgaacggagcgccaccttcctcaaagcccggctcccctgccctcattgagaccaag
gagcccaacgggagcatccacaccagcggctccacgtccgaggagccggatgcccaggct
gacaacccctcgttccccaaccctcgccggaggctgcggcttcaggacctggccgatcgc
gtggtggacgcctccgaggacgagcacgagctcaaccagctgctcaacgaggccctgctg
gagcgggagtccgcccaggtagtgaagaagagaaacaccttcttcctgtccatgcggttc
atggaccgcgagatggaaacccgctactcggtggagaaggagaagcagagtggggccgcc
ttcagctgttcctgcgtcgtcctgctctgcaccgccctggttgagattctcatcgacccc
tggctgatgacaaactatgtgacctttgtggttggcgaggtcctgctcctgaccctgacc
gtctgctcgctggctgccatctttcctcgggcctttcctaagaagatcgtggccttctcg
acttggatcgaccggacgcgctgggccaggaacacctgggccatgctggccatcttcatt
ctggtcatggcaaacgtcgtggacatgcttagctgtctccagtactacatgggacccacc
aacggcacctcaagggtgcagatagaggacggctgcgtggagaaccccaagtattacaac
tacgtcgctgtgctgtccctgatcgccaccatcatgctggtgcaggtcagccacatggtc
aagctgacactcatgctgctcatcgcaggggctgtggccgtcatcaacatctacgcctgg
cgccccatctttgatgaatacgaccgcagacgcttccaggaacacgactttccgatggtg
gccttagagaagatgcaggtactttccagccctgggctcaatggcactgacaggctgccc
ctggtgccatccaagtgctcgatgacggtgatgatcttcgtcatgatgctcagcttctac
tacttctcccgccacgtggagaagctggcacggacactgttcttatggaagattgaggtc
cacgaccagaaggaacgtgtctatgaaatgagacgctggaacgaggccttggtcactaac
atgttgcctgagcacgtggcacgccatttcctggggtccaagaagagagacgaggagctg
tacagtcagtcttatgatgagattggagtcatgtttgcctccctgcccaactttgctgac
ttctacacagaggagagcatcaataacggtggcattgagtgtctgcgcttcctcaatgag
atcatctcagattttgactctctcctggacaatcccaagtttcgggtcatcaccaagatc
aaaaccattggcagcacctacatggcagcttcaggagtcaccccagatgtcaacaccaat
ggctttaccagctccaacaaggagaggtcagacaaggagcgctggcagcacctggcggat
ctggccgacttcgcgctcgccatgaaagacacgctcaccaacatcaacaaccagtccttc
aataacttcatgttgcgcatcggcatgaacaaaggaggggtactggctggcgtcatcgga
gcccggaaaccacactatgacatctggggcaatacagtcaacgtagccagcaggatggag
tccacaggggtcatgggcaacattcaggtggtggaagaaactcaagtcatccttcgagag
tacggcttccgctttgtgaggagagggcccatctttgtgaaagggaagggggagctgcta
accttcttcttgaaggggcgagagaagccagccacgttccctaatggctcctcggttaca
ctgccccaccaggtagtagacaactcctga

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