Orcinus orca (killer whale): 101284416 Help Entry 101284416         CDS       T05247                                  Symbol SPG11 Name (RefSeq) spatacsin isoform X4   KO K19026   spatacsin Organism oor  Orcinus orca (killer whale) Pathway oor05014   Amyotrophic lateral sclerosis oor05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:oor00001]  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     101284416 (SPG11)    05022 Pathways of neurodegeneration - multiple diseases     101284416 (SPG11)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03400 DNA repair and recombination proteins [BR:oor03400]     101284416 (SPG11) DNA repair and recombination proteins [BR:oor03400]  Eukaryotic type   DSBR (double strand breaks repair)    HR (homologous recombination)     Other HR factors      101284416 (SPG11) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Spatacsin_C Motif Other DBs NCBI-GeneID:  101284416 NCBI-ProteinID:  XP_004274157 LinkDB All DBs Position 2:113802895..113879395 Genome browser AA seq 2439 aa AA seqDB search MAADKGAGGAEAVERVLPVLLVPVPAEATGRLGSRAQLHREQEVLGSLTAAGSLHVLPLA PGGRGGGGCRLEGPFRQFVWEDSHNSGTPTDKPRLLALSENNALLICEFSLKDGRCDATI SYSYTEETLQKLVEDQIISISLLSLRILSFHSNTSLLFINEYIILRIIFPERDAEIRVLS CFTLSLPAQAVDRIIDTQLCRGILFVLSRLGWIYIFDTVDGRHVAHVDLALPQEDMYNEQ QQEPAKSSSFTSLKVSQDLDVVVIVSSSNTAIALNLNLYFRQYPGHLLCERTLEDIPIEG PKGIDEDDPVNSDYNMKLTKFSFQVDRSWKAHLSSLNETIKNSKLEGTCCALWFQDILHL EPPESGNHSTSVPNWAFTPQDVMCSQYSFPQKGPAKTSDSGRSWKRIHISEQEEPLELTC MSVTGFTALFTWAVERTGCTIVLWDLETQSMQRFSLGKKCIPVDSGGDQQLCLVLTEDGL SLILFGLTQEEFLNRLMIHGSASTVDSLCHLNGWGRCSIPIHALEAGIENRQLDTVDFFL KSKENLLSPSSKSSVPDQFDHFPSHLYLKHVEELTPALDLLCSAIRENDSETQSKHFSEQ LLNLTLSFLNKQIKELFIHNEGLDEHLQKGVNILTSYINELRTFMIKFPWKLTDAIDEYD VNENVPKVKESNIWEKLSIEEVIANAILNNKIPEAQTFFRINSHSAQRLEELIRIGLDLV FDNLKKNNIKEASELLKNMGFNVKDQLLKICFYTTDKNIRDFLVEILKEKNYFSEKEKRT IDFVHQVEKFYSGHFQENMQIQSFPRYSIKEQDFFKHKSVLDSFLKYDHKDTDKLNKQDH RIVLTWAQWWNQLTQESILLPRISPEEYKSYSPEALWRYLTARHDWFSITLWIGEFQTQN RFASLQQNKWPPLTVDVVDQNTRCNNYMRNEILDTLARNGLFLTSELEDFELFLKRLNRI GGVMQDTLPVQNYRSKDGWDFHCHFILYCLEHSLQYLLYVFLDYYKLSPPNCPFLEKKEL HEAHPWFEFLVQCRQVSSNLTDPKLIFQASLANAQILIPSNQASVSSMLLEGHTLLALAT TMYAPGGVSQVVQNEENENCVKKVDPQLLKMALTPYPKLKTALFPQYTAPSVLPPDITLY HLIQSLLPFDPSRLFGWQSANTLTIGDAASQLPHFSSPDLVNKYAIVERLNFAYYLHHGR PSFAFGTFLVQELTKSKTPKQLIQQVGNEAYVLGLSSFHIPSIGAACVCFLELLGLDSLM LRVDMKVANIILSYTCRNEDAQYNFIRESLAEKLSKLAMGEKSTIEELLVLLEEGIWDSI QQQEIKRLSSESSSQWALVVQFCRLHNLKLSTSYLRECAKANDWLQFIIHSQLHNYHPEE VKSLLQYFSPVLQDHLRLAFENLPSVSKSRMDSDQVCNKSPQELQRNKVEMTDFFEILLQ CSEVPNSWCWLLAEAVKQQAPILSVLASCVQDASAIPCLCVWIITSVEHSVAAEAMGHIQ DSMEGHTWDLEDLSVIWRTLLTRQKSKTLIRGFQLFFKESPLLFMMEMYELCMFFKNYEE AEAKLLEFQKSLETLETAATRVHAIIPAPWLKEHVYFLLKLMLQQCRTQYELGKLLQLFV GREHLFSDGPDVKKLCVLSQILKDTSIAINRVIITSYSLENFQHECRSILEKLETDGYFA LARRVAELAELPVDNLIIEEITQEMQTLKHIDQWSLKQARIDFWKKCHENFKKNSISSKA ASSFFSAQALTACECPAEEGPSSTEERHLLLTLAGHWLAQEDLVPLEELEELEKQIWLCR ITQHTLRGSQEEIGPGCSQQISTSGELSFESLASEFSFSKLAALNTSKYLELNGLPSKDT CENKLNWKEQESLHFLIGRLLDDGCVHEASRVCRYFHFCNQDVALVLHCRALASGEASVD DLHPDIHALLQSPELLEEEEEPGVPLRKVQSTSSLDSQSFVILPPSGEVVTTLETLTSKC LHGKNYCRQVLCLYALAKELGCSYTDVAAQDGEAILRVILASQQPDRCKRAQAFISTQGL EPDTVAELVAEEVTRELLTPSEGTGHKQTFTPTEESQTFLQLTALCQDRTLVGMKLLDKI SSVPHGDLSCTTELLILAHHCFTLTCHMEGIIRVLQAARLLTDNHLAPSEEYGLVVRLLT GIGRYNEMTYIFDLLHKKHYFEVLMRKKLDPSGTLKTALLDYIKRCRPGDSEKHNMIALC FSMCREIGENHEAAACIQLKLIESQPWEDSLKDGHQLKQLLLKALTLMLDAAESYAKDSC VRQALHCHRLTKLITLQIHFLNTGQNTMLINLGRHRLMDCIMALPRFYQASIVAEAYDFV PDWAEILYQQVILKGDFNYLEEFKQQRLLRSSIFEEISIKCKHHQPTDLAVKNLKKLLTY CEDVYLYYKLAYEHKFYDVVNVLLKDPQTGCCLKDMLAG NT seq 7320 nt NT seq  +upstreamnt  +downstreamnt atggctgcagacaagggggctggaggcgctgaagccgtggagcgggttctacccgtgttg ttggtgccggtccccgccgaggcaacagggcgtctgggatcccgggcgcagttgcacagg gagcaggaggttctggggagcttgacggctgcaggcagccttcacgtgcttcccttggcg cccggcggccggggcgggggcggctgccgcctggaaggcccttttcggcagtttgtatgg gaggactctcataacagtgggacaccaacagacaagcccagactgcttgctcttagtgaa aataatgcactgctcatctgtgaatttagtttgaaagatggaagatgtgatgcaaccatt tcatatagctatactgaggagacattgcaaaagctcgttgaagatcaaattatcagtatt tccttattatctttgagaattctgtcatttcacagtaacacatcattattgttcatcaat gaatatatcatcctgcgcattatatttcctgaaagagatgctgagattagggtactcagc tgtttcacattatccttacctgcacaggcagtggacaggattattgacacacagctctgc agaggaattctttttgttttgagtcgtttaggctggatctacatttttgacactgtggat ggtagacatgtagctcatgtggatttggcacttcctcaagaagatatgtataatgagcag caacaagagccagccaagagttcttcctttacttcattgaaagtgtctcaagacctagat gttgtagtgattgtcagctcctccaacactgcaattgctcttaacttaaatttgtatttc aggcaatacccaggacacctactatgtgaaagaacactagaagacattcctattgaaggc cctaaggggatagatgaagatgatcctgttaattctgactacaacatgaaactgaccaag ttttccttccaagttgatcggtcttggaaagcccacctgtcatcactgaatgaaacaata aagaactccaagctggaaggtacctgttgtgctctgtggttccaggatattttgcatttg gagcctcctgaatctggtaaccacagtaccagtgtgccaaactgggccttcactccacag gatgtaatgtgcagccagtatagttttccacagaaaggtcctgccaagaccagtgattca ggaagatcatggaaaagaatacacatcagtgaacaggaggaaccccttgagcttacatgt atgtctgtgacaggcttcactgcgctgtttacttgggcagttgaaaggacgggctgtacc attgtcctgtgggatttggagacccagagcatgcagcgtttttcgctgggcaagaagtgt attcctgtagacagtggtggagaccagcaactgtgccttgttttgacagaagatggactc tctctgattttgtttggtttgactcaagaggaatttttaaataggctaatgatccatgga agtgccagcactgtggactctctttgccatctcaatggttgggggaggtgctccatcccc atacatgcgctagaggcaggaatagaaaatcgtcagctggacacagtagatttctttttg aagagcaaggaaaatcttttgagtccatcctcaaaatcttctgtacctgatcagtttgat cactttccatcccatttatatttaaaacatgtggaagagctgacaccagcattggattta ctttgctcagcaattagagaaaatgattctgaaacccagagcaaacacttttcggaacag ttgcttaatcttacactgtctttccttaacaaacaaataaaggagctttttattcacaat gaagggctagatgaacatctacagaaaggagtgaacattttgaccagctacattaatgaa cttcgaaccttcatgataaagtttccttggaagctaacagatgctatagatgaatatgat gtaaatgaaaatgtccccaaagtaaaggagagcaatatatgggagaagctcagcattgag gaagttattgccaatgccattttaaacaacaaaataccagaggcacaaactttcttcagg attaacagtcattctgctcaaagactcgaggagttgattagaataggcctagatttggtc tttgacaatttgaaaaagaataatataaaggaagcctctgagcttttgaagaatatgggc tttaatgtaaaagaccagttgctcaagatatgcttctatacaactgataaaaacatacgg gactttttggttgaaattttaaaagaaaaaaattatttttctgaaaaagaaaaaagaact atagacttcgtgcatcaagttgagaagttttattcaggacatttccaagaaaatatgcag atccagtcttttcccaggtattcgataaaggaacaagattttttcaagcacaagtctgtt ttggactcattcctgaaatatgatcataaagatacagataaacttaacaagcaagatcac agaattgtgttaacttgggctcagtggtggaatcaactaacacaagaatccatccttctc cccaggataagtccagaagaatacaaatcatattctcccgaagccctctggagatacctc acagctcgccatgattggttcagcattaccttgtggattggagaatttcagacccagaat agatttgcctcacttcagcagaacaaatggccccctctgactgtggacgttgttgatcag aatactcgctgcaacaactacatgaggaatgaaattttagatacgctggccaggaatgga ctttttcttacatctgaactagaagactttgaactctttctcaaaagactgaaccgtatt gggggcgtgatgcaagataccctccctgttcaaaactataggtccaaagatggttgggat ttccattgtcacttcattctctattgtttggaacacagtctgcagtatcttctttatgtc tttcttgactattacaaacttagtcctccaaattgtccctttttggaaaaaaaagaatta catgaagctcacccttggtttgaatttttagtccagtgtcgacaagtttccagtaattta acagatcccaaactgatcttccaggctagccttgcaaatgctcagatactgattcccagc aaccaggccagtgtaagcagtatgctattggaaggacataccctcctggcccttgctacc acaatgtatgcccctgggggcgtcagccaggttgttcagaatgaagaaaatgagaactgt gtgaagaaagtagatccccagctactgaagatggcattaactccgtaccccaagcttaaa actgctctcttcccacagtacactgcccctagtgtcctgccaccagatattacactctac cacctgattcagtcattattgccctttgatcctagcagattgtttggctggcagtctgcc aacacactgactataggagatgcagcgagtcagctcccacatttctctagccctgacctg gttaataaatatgctatagtagaacgtctgaattttgcttattatttacatcatggacga ccatcgtttgcgtttggtacttttctggttcaggaattaaccaagagcaagacccccaag cagctaatccagcaagtaggcaatgaagcctatgttttagggctctcctccttccacata ccatcaataggagctgcctgtgtttgtttcttagaactgcttggcctcgacagcctcatg ctcagagttgatatgaaagtggccaatataattttgagctacacgtgtagaaatgaagat gctcagtacaactttatcagagagtctctagctgaaaaactatctaaactggctatgggt gaaaagtcaaccatagaagaattgcttgttctcttagaagaaggtatatgggacagcatt cagcagcaggaaataaagaggttatccagtgaatccagcagccagtgggcattagtggta caattctgcaggctccacaatctgaaactgagcacatcttaccttagagaatgtgccaaa gcaaatgattggttacagtttattattcacagccaactccataattaccacccagaggag gtgaaatctcttctccaatatttcagccctgttcttcaagaccacttaagactggctttt gagaacttgccctcagtgtccaagtctagaatggacagtgatcaagtctgcaacaagtcc ccgcaggaactgcaaagaaacaaagtagagatgaccgatttctttgaaattctgcttcag tgctcagaggtgccaaactcctggtgctggctcctggcagaagcagtgaaacaacaggcc ccaatccttagtgtcctggcctcatgtgtccaggacgccagtgctattccttgcctctgt gtttggatcatcacttctgtggagcacagtgttgcagctgaagcaatgggacacattcag gactcaatggagggccatacttgggaccttgaggacctctcagtcatctggaggacatta ttaacacggcagaagagcaaaactctcatcagaggtttccagcttttctttaaggagtcc ccattactcttcatgatggagatgtatgaactgtgtatgttcttcaagaattatgaggaa gccgaagctaaacttctggagttccagaagagccttgaaactcttgaaacggctgccaca agggtccacgctatcattcctgccccatggctgaaggagcatgtgtattttcttttgaag cttatgctgcagcagtgtaggacccagtatgagctggggaagcttttacagctgtttgtt ggaagagagcatctcttctctgatggtccagatgtgaagaagctgtgtgtccttagccaa attttgaaggatacatccatagccattaatcgtgtaattattaccagctacagccttgag aattttcagcatgaatgtagatcaattttagaaaaactggagacagatggatactttgct ttggccagaagggtagcagaactagctgagctacctgtggacaacttgattattgaagag ataacacaggaaatgcagaccttaaaacacattgaccagtggtccctgaaacaagcaaga attgatttctggaaaaaatgtcatgagaattttaagaaaaattccatttcaagcaaagca gcttcttcctttttctcagcccaggctcttacggcatgtgagtgcccagctgaagaggga ccaagcagcactgaggagcgccatctgctcctcactctggcaggacactggcttgcccag gaggacctggtgcctttggaggagctggaggagctagagaagcagatctggctctgccgc atcacccagcacaccctcaggggaagccaggaggaaataggccccggatgttctcaacag atttcaactagtggtgaactttcctttgaaagcttagccagtgagttttcattctctaag ttggctgctctgaacacatcaaaatacttagaattgaatggccttccgtccaaagacact tgtgagaacaaactgaactggaaggagcaggagtccctacactttttgattgggcgccta ttggatgatggctgtgtgcatgaagcaagtagagtgtgccgatattttcatttctgtaac caagatgttgccttggtgttgcattgcagagcactagcttcaggggaagctagtgtggat gacctgcacccggacatccatgctctcttacaaagtcctgagctgcttgaggaagaagaa gaacctggcgttcctctaaggaaagtccaaagcacttcaagtttggacagtcagtcattt gtgatactgccccccagtggtgaagtggtgactactctggaaactctgacaagcaaatgc ctccatgggaagaattattgtcggcaggtcctctgtctctatgcacttgccaaggagttg ggctgttcctacacagatgtcgctgcccaggatggtgaggccattctccgggtaatcttg gcctctcagcagcctgaccgatgcaagcgagctcaagccttcatcagcacccagggcctc gagccagacacagtggctgaacttgtggctgaagaggtgacccgggagctgctgacccca tcagagggaacaggacataagcagacgttcaccccaacagaggaaagccagacgtttctt cagctgactgctctgtgtcaagaccgcaccttggtaggcatgaagttgttggataagatt tcctccgttccccatggggacttgtcttgcaccacagagctgctgatcctggctcatcac tgcttcacactgacatgccacatggagggcatcatccgagtcctgcaggccgcccggctg ctcacagacaaccacttggcccccagtgaggagtacggactggtggtgcgactcctcact ggcattggaaggtacaatgagatgacatacatatttgatttgctgcataaaaaacactac tttgaagtgctgatgaggaagaaattggacccgagtggtaccctgaagacggccctactg gactacatcaaacgctgccgccctggggacagtgagaagcacaacatgattgccctgtgt ttcagcatgtgccgggagattggggagaaccatgaggcagctgcctgcatccaactgaaa ttgattgagtctcagccctgggaggacagcctcaaggatgggcaccaactgaagcagctg ctgctgaaggccctgactctgatgctggatgcagcagagagttatgccaaggactcctgc gtgcgacaggccctgcactgtcaccggctcaccaagttgataacactgcagattcacttt ctgaacaccggccagaacacaatgctcatcaacctgggccgccacaggctgatggactgt atcatggccctacctcggttctaccaggcttctattgtggctgaggcctatgactttgtt cctgattgggctgaaattttataccaacaagtgattcttaaaggagactttaattacctg gaagaatttaagcagcaaaggttattaagatccagtatatttgaagaaatttcaataaaa tgtaaacatcatcagcctactgacttagctgtgaaaaacctgaagaagttactcacatat tgtgaagacgtctacttgtattacaagctggcatacgaacacaaattttatgacgttgta aatgtgcttctgaaggaccctcagacaggttgctgtctaaaggacatgctagcaggttag

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