Orcinus orca (killer whale): 101287555
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Entry
101287555 CDS
T05247
Symbol
TGFBR1
Name
(RefSeq) TGF-beta receptor type-1 isoform X2
KO
K04674
TGF-beta receptor type-1 [EC:
2.7.11.30
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04010
MAPK signaling pathway
oor04060
Cytokine-cytokine receptor interaction
oor04068
FoxO signaling pathway
oor04144
Endocytosis
oor04218
Cellular senescence
oor04350
TGF-beta signaling pathway
oor04371
Apelin signaling pathway
oor04380
Osteoclast differentiation
oor04390
Hippo signaling pathway
oor04520
Adherens junction
oor04659
Th17 cell differentiation
oor04926
Relaxin signaling pathway
oor04933
AGE-RAGE signaling pathway in diabetic complications
oor05142
Chagas disease
oor05161
Hepatitis B
oor05166
Human T-cell leukemia virus 1 infection
oor05200
Pathways in cancer
oor05210
Colorectal cancer
oor05212
Pancreatic cancer
oor05220
Chronic myeloid leukemia
oor05225
Hepatocellular carcinoma
oor05226
Gastric cancer
oor05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101287555 (TGFBR1)
04350 TGF-beta signaling pathway
101287555 (TGFBR1)
04390 Hippo signaling pathway
101287555 (TGFBR1)
04371 Apelin signaling pathway
101287555 (TGFBR1)
04068 FoxO signaling pathway
101287555 (TGFBR1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
101287555 (TGFBR1)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101287555 (TGFBR1)
09143 Cell growth and death
04218 Cellular senescence
101287555 (TGFBR1)
09144 Cellular community - eukaryotes
04520 Adherens junction
101287555 (TGFBR1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
101287555 (TGFBR1)
09152 Endocrine system
04926 Relaxin signaling pathway
101287555 (TGFBR1)
09158 Development and regeneration
04380 Osteoclast differentiation
101287555 (TGFBR1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101287555 (TGFBR1)
09162 Cancer: specific types
05210 Colorectal cancer
101287555 (TGFBR1)
05212 Pancreatic cancer
101287555 (TGFBR1)
05225 Hepatocellular carcinoma
101287555 (TGFBR1)
05226 Gastric cancer
101287555 (TGFBR1)
05220 Chronic myeloid leukemia
101287555 (TGFBR1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101287555 (TGFBR1)
05161 Hepatitis B
101287555 (TGFBR1)
09174 Infectious disease: parasitic
05142 Chagas disease
101287555 (TGFBR1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
101287555 (TGFBR1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101287555 (TGFBR1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101287555 (TGFBR1)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
101287555 (TGFBR1)
Protein kinases [BR:
oor01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR1 family [OT]
101287555 (TGFBR1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
TGF_beta_GS
Activin_recp
Pkinase_fungal
APH
FTA2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
101287555
NCBI-ProteinID:
XP_004271524
LinkDB
All DBs
Position
6:88023108..88090445
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AA seq
499 aa
AA seq
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MEAAAAAPRPWLLLLVLAAAATLVPEVTALQCFCHLCTKDNFTCVTDGLCFVSVTETTDK
VIHNSMCIAETDLIPRDRPFVCAPSSKTGSVTTTYCCNQDHCNKIELPTVGKPSSGLGPV
ELAAVIAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDM
TTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFR
EAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIK
LALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDT
IDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDY
QLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLT
ALRIKKTLSQLSQQEGIKM
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcggccgctgctccgcgtccctggctgctcctcctcgtgctggcggcggcg
gcaacgctggtcccggaggtgacggcattacagtgtttctgccacctttgtacaaaagac
aattttacttgtgtcacagatgggctctgctttgtctctgtcacagagaccacagacaaa
gttatacataatagcatgtgtatagctgaaaccgacctaattccacgagacaggccattt
gtatgtgcaccatcttcaaaaactgggtctgttactacaacatattgctgcaatcaggac
cactgcaataaaatagaactcccaactgttggaaagccatcatctggccttggtcctgtc
gaactggcagctgtcattgctggaccagtatgcttcgtctgcatctcactcatgttgatg
gtctatatctgccataaccgcactgtcattcaccatcgagtgccaaatgaagaagatcct
tcattagatcgcccctttatttcagagggtactacgttaaaagatttaatttatgatatg
acaacatcgggttctggatcaggtttaccattgcttgttcagaggacaattgcgagaact
attgtgttacaagaaagtattggcaaaggtcgttttggagaagtttggcgaggaaaatgg
agaggagaagaagttgctgttaaaatattctcctctagagaagaacgttcatggttccgt
gaggcagagatttatcagaccgtcatgttacgtcatgaaaacatcttgggatttatagca
gcagacaataaagacaatggtacatggactcagctctggttggtgtcagattatcatgag
catggatccctttttgattacttgaacagatacacagttactgtggaaggaatgataaaa
ctcgctctgtccacagcaagtggacttgcccatcttcacatggagatagttggtacccaa
ggaaaaccagccattgctcatagggatttgaaatcaaagaatatcttggtaaagaagaat
ggaacttgctgtattgcagacttgggactggcagtaagacatgattcggccacagataca
attgatattgctccaaaccacagagtgggaacaaaaaggtacatggcccctgaagttcta
gatgattccataaatatgaaacactttgaatccttcaaacgtgctgacatctatgcaatg
ggactagtattctgggaaatagctcgacgatgttccattggtggaattcatgaagattac
cagctgccttattatgatcttgtaccttctgatccatcagttgaagaaatgagaaaagtt
gtttgtgaacagaagttaaggccaaatattccaaacagatggcagagctgtgaagccttg
agagtgatggctaaaattatgagagaatgttggtatgccaatggagcagctaggcttaca
gctctgcggattaagaaaacattatcacagctcagtcagcaggaaggcatcaaaatgtaa
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