Orcinus orca (killer whale): 101287620
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Entry
101287620 CDS
T05247
Symbol
GAD1
Name
(RefSeq) glutamate decarboxylase 1 isoform X1
KO
K01580
glutamate decarboxylase [EC:
4.1.1.15
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00250
Alanine, aspartate and glutamate metabolism
oor00410
beta-Alanine metabolism
oor00430
Taurine and hypotaurine metabolism
oor00650
Butanoate metabolism
oor01100
Metabolic pathways
oor04727
GABAergic synapse
oor04940
Type I diabetes mellitus
Module
oor_M00027
GABA (gamma-Aminobutyrate) shunt
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
101287620 (GAD1)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
101287620 (GAD1)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
101287620 (GAD1)
00430 Taurine and hypotaurine metabolism
101287620 (GAD1)
09150 Organismal Systems
09156 Nervous system
04727 GABAergic synapse
101287620 (GAD1)
09160 Human Diseases
09167 Endocrine and metabolic disease
04940 Type I diabetes mellitus
101287620 (GAD1)
Enzymes [BR:
oor01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.15 glutamate decarboxylase
101287620 (GAD1)
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GFIT
Motif
Pfam:
Pyridoxal_deC
Aminotran_5
Beta_elim_lyase
DegT_DnrJ_EryC1
SepSecS
OKR_DC_1
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
101287620
NCBI-ProteinID:
XP_004267334
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Position
7:59209793..59250840
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AA seq
594 aa
AA seq
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MASSTPSSSATSSNAGADPNTTNLRPTTYDTWCGVAHGCTRKLGLKICGFLQRTNSLEEK
SRLVSAFKERQSSKNLLSCENSDRDGRFQRTETDFSNLFARDLLPAKNGEEQTVQFLLEV
VDILLNYVRKTFDRSTKVLDFHHPHQLLEGMEGFNLELSDHPESLEQILVDCRDTLKYGV
RTGHPRFFNQLSTGLDIIGLAGEWLTSTANTNMFTYEIAPVFVLMEQITLKKMREIIGWS
SKDGDGIFSPGGAISNMYSIMAARYKYFPEVKTKGMAAVPKLVLFTSEHSHYSIKKAGAA
LGFGTDNVILIKCNERGKIIPADLEAKILEAKQKGYIPLYVNATAGTTVYGAFDPIQEIA
DICEKYNLWLHVDAAWGGGLLMSQKHRHKLSGIERANSVTWNPHKMMGVLLQCSAILVKE
KGILQGCNQMCAGYLFQPDKQYDVSYDTGDKAIQCGRHVDIFKFWLMWKAKGTVGFENQI
NKCLELAEYLYAKIKNREEFEMVFDGEPEHTNVCFWYIPQSLRGVLDSPERREKLHKVAP
KIKALMMESGTTMVGYQPQGDKANFFRMVVSNPAATQSDIDFLIEEIERLGQDL
NT seq
1785 nt
NT seq
+upstream
nt +downstream
nt
atggcgtcttcgaccccttcttcgtccgcaacctcctcgaacgcgggagcggaccccaat
actaccaacctgcgccccacaacgtatgacacctggtgcggcgtggcccatggatgcacc
agaaaactggggctgaagatctgtggcttcttgcaaaggaccaacagcctggaagagaag
agcaggcttgtgagtgccttcaaggagaggcagtcctccaagaatctgctttcctgtgaa
aacagcgacagggatggccgcttccagcgcacagagaccgacttctccaacctgtttgct
cgagatctgcttccggctaagaatggggaggagcaaactgtgcagttcctgctggaggtg
gtagacatactcctcaactacgtccgcaagacattcgatcgctccaccaaggtgctggac
ttccaccacccccaccagctgctggaaggcatggagggcttcaacctggaactctctgac
caccctgagtccctggagcagatcctggttgactgcagagacaccctgaaatatggcgtc
cgcacaggtcatcctcgatttttcaaccagctctccactggattggatatcattggatta
gctggcgaatggctgacatcaactgccaataccaatatgtttacatatgaaattgcacca
gtgtttgtcctcatggagcaaataacacttaagaagatgagagagataattggatggtca
agtaaagatggtgatgggatattttctcctgggggagccatatccaacatgtacagcatc
atggcggctcgctacaagtacttcccggaagttaagacaaagggcatggcagccgtaccc
aagctggtcctcttcacctcagaacacagtcactattccataaagaaagctggggctgca
cttggctttggaaccgacaatgtgattttgataaagtgcaatgaaagggggaagataatt
ccagctgatttagaggcaaaaattcttgaagccaagcaaaagggatacattcctctgtat
gtcaatgcaactgccggcacgactgtttatggcgcttttgatcccatacaggagattgca
gatatatgtgagaaatacaacctctggctgcatgtcgatgctgcctggggtggcgggctg
ctcatgtctcagaagcaccgccataaactcagcggcatagaaagggccaactcagtcacc
tggaatcctcacaagatgatgggcgtgctgttgcagtgctccgccatcctggtcaaggaa
aagggtatcctccaaggatgcaaccagatgtgtgcagggtacctcttccagccagacaag
cagtatgacgtctcctacgacactggggataaagccattcagtgtggccgccatgtggac
atcttcaagttctggctgatgtggaaagcaaagggcacagtgggctttgaaaatcagatc
aacaaatgcttggagctggcagaatacctctatgccaagattaaaaacagagaggaattt
gagatggtttttgatggtgagcctgagcacacgaatgtctgtttctggtatattccacaa
agcctcaggggcgttctggatagccctgagcgccgggaaaaactacacaaggtggccccg
aaaatcaaagccctgatgatggagtctggcacgaccatggttggctaccagcctcagggg
gacaaggccaacttcttccggatggtcgtctccaacccagccgctacccagtctgatatc
gacttcctcattgaggaaatagagaggctgggccaggatctgtaa
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