Orcinus orca (killer whale): 101288799
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Entry
101288799 CDS
T05247
Symbol
HMGCL
Name
(RefSeq) hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00280
Valine, leucine and isoleucine degradation
oor00650
Butanoate metabolism
oor01100
Metabolic pathways
oor04146
Peroxisome
Module
oor_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
101288799 (HMGCL)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
101288799 (HMGCL)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101288799 (HMGCL)
Enzymes [BR:
oor01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
101288799 (HMGCL)
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GFIT
Motif
Pfam:
HMGL-like
Motif
Other DBs
NCBI-GeneID:
101288799
NCBI-ProteinID:
XP_004285705
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Position
1:194296493..194313235
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AA seq
325 aa
AA seq
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MATVKKAPLWRLVGLASLRAVSTSSVGTFPKQVKIVEVGPRDGLQNEKNIIPTPMKIKLI
DMLSEAGLPVIEATSFVSPKWVPQMADHAEVMKGIQKFPGISYPVLTPNFKGFQAAVAAG
AKEVAVFGAASELFSKKNINCSIDESVQRFDEILKAARAASIPVRGYVSCVLGCPYEGKI
SPAKVAEVAKKMYSVGCYEISLGDTIGVGTPGTMKDMLSAVMHEVPVAALAVHCHDTYGQ
ALANTLMALQMGVSVVDSSVAGLGGCPYAHGASGNLATEDLVYMLAGLGVHTGVNLHKLL
EAGAFICQALNRRTSSKVAQATCKL
NT seq
978 nt
NT seq
+upstream
nt +downstream
nt
atggcgacagtgaagaaggcacccctgtggagactggtgggcttggcgtccctccgggct
gttagcacctcatctgtgggtactttcccaaagcaagtgaaaattgtggaagttggtccc
cgagacggactacaaaatgaaaagaatattatacctactccaatgaaaatcaaactgata
gacatgctttccgaagcaggactccctgttatagaagccaccagctttgtgtctcccaaa
tgggttccccagatggctgaccacgctgaagtcatgaagggcatccagaaatttcccggc
atcagctacccagtgctgaccccaaatttcaaaggcttccaggcagcggttgctgccgga
gccaaggaagtggctgtctttggagctgcctccgagctcttcagcaagaagaacatcaac
tgctccatagatgagagtgtgcagcggtttgacgaaatcttgaaggcagctcgggcagcc
agtatccctgtgcgggggtacgtctcctgtgtgctcggatgcccctacgaagggaagatc
tccccggctaaagtagctgaggttgccaagaagatgtactcggtgggctgctatgagatc
tctctgggagacaccattggcgtgggcacccctgggaccatgaaggatatgctgtccgct
gtcatgcatgaggtgccagtggctgccctggctgtccactgccatgacacctatggccag
gccctggccaacaccttgatggccctgcagatgggagtgagtgtcgtggactcttctgtg
gcgggactgggaggctgtccctatgcacacggagcatcaggaaacttggccaccgaggac
ctggtctacatgctggccggcttgggcgttcacacgggtgtgaacctccacaagctcctg
gaagctggggcctttatctgtcaagccctgaacagaagaaccagctccaaagtggctcag
gctacctgtaaactgtga
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