Orcinus orca (killer whale): 101288813
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Entry
101288813 CDS
T05247
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00230
Purine metabolism
oor01100
Metabolic pathways
oor04927
Cortisol synthesis and secretion
oor04934
Cushing syndrome
oor05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101288813 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
101288813 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
101288813 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101288813 (PDE8B)
Enzymes [BR:
oor01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
101288813 (PDE8B)
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Gene cluster
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DHH
DUF4194
Motif
Other DBs
NCBI-GeneID:
101288813
NCBI-ProteinID:
XP_049563694
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All DBs
Position
3:complement(124328166..124713583)
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AA seq
885 aa
AA seq
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MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPLHGLFVQTDAADAIPPSRASW
PPGAARGRRARGELGSGSSAGSTAPAATTCRGRSRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASGDYEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDKNKQIHKVHRDSGDNSQTESHSFRHKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVPQSHSHLGMPVTI
NDVPPSIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSETTLRAW
LQVIESNYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPTGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPTLMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggccccgcggccccactg
cacggcctcttcgtccagaccgacgccgccgacgccatccccccgagccgcgcgtcctgg
ccccccggtgccgcccgcggccgcagggcccgcggtgagctgggcagcggcagcagcgcg
ggctccacggcccccgcggcgaccacctgcaggggccggagtcgccactgctgcagcagc
gcggaggccgagacccagaccagctacaccagcgtcaagcaggtctcttctgcagaggta
cgcatcgggcccatgagactgacgcaggatcctatccaggttttgctgatctttgcaaag
gaagacagtcagagtgatggattctggtgggcctgtgacagagccggttacagatgtaat
attgctcggactccggagtcagccctggaatgctttctagataaacatcatgagattatt
gtgatcgaccacagacaaactcgaaactttgatgcagaagcagtgtgcaggtcgatccgg
gccacaaatccctcggagcacacggtgattcttgcggtggtttcacaagcatccggcgac
tatgaagaggcctcagtcctccctcttctgcacgcaggcttcaaccggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcacagttcaagttaagggcctgtaattcagtgtttacagcattagaccactgtcatgaa
gccatagaaatcacaagcgatgaccacgtgattcagtatgtcaacccagccttcgaaagg
atgatgggctaccacaaaggtgagctcctggggaaagaactcgccgagctgcccaaaagt
gacaagaaccgggcggaccttcttgacaccatcaacacctgcatcaagaagggcaaggag
tggcagggggtttactatgccagacggaaatccggcgacagcatccaacagcatgtgaag
atcactccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactg
tgttgtaccactgacaaaaataagcagattcacaaggttcatcgtgactcaggagataat
tctcaaacagagtctcattcattcagacacaagaacaggaggaaagagtccattgatgtg
aaatcaatatcatctcgaggcagtgatgcaccaagcctacagaatcgtcgctacccatcc
atggcaaggatccattccatgaccatcgaggctcccatcacaaaggttataaatataatc
aatgcagcccaagaaaacagtcctgtcacagtagcagaagccttggacagagttttagaa
attttacggaccacagaactgtactcccctcagctgggtaccaaagatgaagatccccac
accagtgatctcgtgggaggcctgatgactgatggcttgagaaggttgtcaggaaacgag
tatgtgttcactaagaatgtgccccagagtcacagtcaccttgggatgccagtaaccatc
aacgatgtccccccttctatcgctcaattacttgataatgaggaaagctgggagttcaac
atatttgaattggaagctgtgacacacaaaaggccattggtttacctgggcttaaaagtc
ttttcccggtttggagtatgtgaatttttacactgttctgaaactacccttcgggcctgg
ctccaagtgattgaatccaactaccactcctccaacgcttaccacaactccactcatgcc
gctgatgtcctgcacgccactgccttcttcctcggaaaagaaagagtgaagggaagcctc
gatcagctagatgaggtggctgccctgattgctgccacagtccatgacgtggatcaccca
ggaaggaccaactctttcctgtgcaacgcaggcagtgaactcgccgtgctctataatgac
actgctgtcttggagagtcaccacacagccctggccttccagctcacggtcaaggacagc
aaatgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctatt
attgatatggttttagcaacagagatgacaaaacactttgaacatgtgaacaaatttgtg
aacagcatcaacaagccaatggcagctgagattgaaggcagtgactgtgaatgcaaccct
actgggaagaactttcctgaaaatcaaatcctgattaagcgcatgatgattaagtgtgct
gacgtggccaatccatgccgccccctggacctatgtatcgaatgggccggaaggatctcc
gaggagtactttgcacagactgatgaagagaagagacaggggctacctgtagtgatgcca
gtattcgaccggaatacctgtagcatccccaagtcccagatctcctttattgactacttc
ataacagacatgtttgatgcttgggatgcctttgcacacctgccaaccctgatgcaacat
ttggccgataactacaaacactggaagacgttagatgacctaaagtgcaaaagtctgagg
cttccatctgacagctaa
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