KEGG   Orcinus orca (killer whale): 101289477
Entry
101289477         CDS       T05247                                 
Symbol
NFKBIA
Name
(RefSeq) NF-kappa-B inhibitor alpha
  KO
K04734  NF-kappa-B inhibitor alpha
Organism
oor  Orcinus orca (killer whale)
Pathway
oor04024  cAMP signaling pathway
oor04062  Chemokine signaling pathway
oor04064  NF-kappa B signaling pathway
oor04210  Apoptosis
oor04380  Osteoclast differentiation
oor04620  Toll-like receptor signaling pathway
oor04621  NOD-like receptor signaling pathway
oor04622  RIG-I-like receptor signaling pathway
oor04623  Cytosolic DNA-sensing pathway
oor04625  C-type lectin receptor signaling pathway
oor04657  IL-17 signaling pathway
oor04658  Th1 and Th2 cell differentiation
oor04659  Th17 cell differentiation
oor04660  T cell receptor signaling pathway
oor04662  B cell receptor signaling pathway
oor04668  TNF signaling pathway
oor04722  Neurotrophin signaling pathway
oor04920  Adipocytokine signaling pathway
oor04926  Relaxin signaling pathway
oor04931  Insulin resistance
oor04936  Alcoholic liver disease
oor05132  Salmonella infection
oor05134  Legionellosis
oor05135  Yersinia infection
oor05140  Leishmaniasis
oor05142  Chagas disease
oor05145  Toxoplasmosis
oor05160  Hepatitis C
oor05161  Hepatitis B
oor05162  Measles
oor05163  Human cytomegalovirus infection
oor05164  Influenza A
oor05166  Human T-cell leukemia virus 1 infection
oor05167  Kaposi sarcoma-associated herpesvirus infection
oor05168  Herpes simplex virus 1 infection
oor05169  Epstein-Barr virus infection
oor05170  Human immunodeficiency virus 1 infection
oor05171  Coronavirus disease - COVID-19
oor05200  Pathways in cancer
oor05203  Viral carcinogenesis
oor05208  Chemical carcinogenesis - reactive oxygen species
oor05215  Prostate cancer
oor05220  Chronic myeloid leukemia
oor05222  Small cell lung cancer
oor05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oor05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oor00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    101289477 (NFKBIA)
   04668 TNF signaling pathway
    101289477 (NFKBIA)
   04024 cAMP signaling pathway
    101289477 (NFKBIA)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    101289477 (NFKBIA)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101289477 (NFKBIA)
   04621 NOD-like receptor signaling pathway
    101289477 (NFKBIA)
   04622 RIG-I-like receptor signaling pathway
    101289477 (NFKBIA)
   04623 Cytosolic DNA-sensing pathway
    101289477 (NFKBIA)
   04625 C-type lectin receptor signaling pathway
    101289477 (NFKBIA)
   04660 T cell receptor signaling pathway
    101289477 (NFKBIA)
   04658 Th1 and Th2 cell differentiation
    101289477 (NFKBIA)
   04659 Th17 cell differentiation
    101289477 (NFKBIA)
   04657 IL-17 signaling pathway
    101289477 (NFKBIA)
   04662 B cell receptor signaling pathway
    101289477 (NFKBIA)
   04062 Chemokine signaling pathway
    101289477 (NFKBIA)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    101289477 (NFKBIA)
   04926 Relaxin signaling pathway
    101289477 (NFKBIA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    101289477 (NFKBIA)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    101289477 (NFKBIA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101289477 (NFKBIA)
   05208 Chemical carcinogenesis - reactive oxygen species
    101289477 (NFKBIA)
   05203 Viral carcinogenesis
    101289477 (NFKBIA)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101289477 (NFKBIA)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    101289477 (NFKBIA)
   05215 Prostate cancer
    101289477 (NFKBIA)
   05222 Small cell lung cancer
    101289477 (NFKBIA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101289477 (NFKBIA)
   05170 Human immunodeficiency virus 1 infection
    101289477 (NFKBIA)
   05161 Hepatitis B
    101289477 (NFKBIA)
   05160 Hepatitis C
    101289477 (NFKBIA)
   05171 Coronavirus disease - COVID-19
    101289477 (NFKBIA)
   05164 Influenza A
    101289477 (NFKBIA)
   05162 Measles
    101289477 (NFKBIA)
   05168 Herpes simplex virus 1 infection
    101289477 (NFKBIA)
   05163 Human cytomegalovirus infection
    101289477 (NFKBIA)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101289477 (NFKBIA)
   05169 Epstein-Barr virus infection
    101289477 (NFKBIA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101289477 (NFKBIA)
   05135 Yersinia infection
    101289477 (NFKBIA)
   05134 Legionellosis
    101289477 (NFKBIA)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    101289477 (NFKBIA)
   05140 Leishmaniasis
    101289477 (NFKBIA)
   05142 Chagas disease
    101289477 (NFKBIA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101289477 (NFKBIA)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101289477 (NFKBIA)
   04931 Insulin resistance
    101289477 (NFKBIA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:oor03000]
    101289477 (NFKBIA)
   04131 Membrane trafficking [BR:oor04131]
    101289477 (NFKBIA)
Transcription factors [BR:oor03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   RHR (Rel homology region) Ankyrin only
    101289477 (NFKBIA)
Membrane trafficking [BR:oor04131]
 Autophagy
  Chaperone mediated autophagy (CMA)
   Selective cargos
    101289477 (NFKBIA)
SSDB
Motif
Pfam: Ank_2 Ank Ank_3 Ank_5 Ank_4 ANK_LRRK2
Other DBs
NCBI-GeneID: 101289477
NCBI-ProteinID: XP_004270018
LinkDB
Position
2:complement(138415093..138418667)
AA seq 314 aa
MFQPAEPGQEWAMEGPRDALKKERLLDDRHDSGLDSMKDEEYEQMVKELREIRLEPQEAP
RGAEPWKQQVTEDGDSFLHLAIIHEEKVLTMEVVRQVKGDLAFLNFQNNLQQTPLHLAVI
TNQPEIAEALLEAGCDPELRDFRGNTPLHLACEQGCLASVGVLTQPRGTQHLHSILQATN
YNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTALHLAVDLQNPDLVSLLLKCG
ADVNRVTYQGYSPYQLTWGRPSTRIQQQLGQLTLENLQMLPESEDEESYDTESEFTEDEL
PYDDCVLGGQRLTL
NT seq 945 nt   +upstreamnt  +downstreamnt
atgttccagcccgcggagcccggccaggagtgggccatggagggcccccgggacgcactc
aagaaggagcggctgctggacgaccgccacgacagcggcctggactccatgaaggacgag
gagtacgagcagatggtgaaagagctaagggagatccgcctcgagcctcaggaggcgccg
cgcggcgccgagccttggaagcagcaggtcaccgaggacggagactcgttcctgcacttg
gccatcatccatgaagagaaggtgctgaccatggaagtggtccgccaagtgaagggagac
ctggcgttcctcaacttccagaacaacctgcagcagactcctctccacttggcggtgatc
accaaccagccagagatcgctgaggcacttctggaagctggctgtgatcctgagctccga
gactttcgaggaaatacccccttacaccttgcctgtgagcaaggctgcctggccagtgtg
ggagtcctgactcagccccgcgggacccagcacctccactccatcctacaagccaccaac
tacaatggtcacacgtgtctgcatttggcctctattcatggctacctgggcatcgtggag
ctgttggtgtccttgggtgctgatgtcaacgcacaggagccctgcaatggccgaactgcc
ctccatctcgcggtggacctgcagaatcccgacctggtgtcgctcttgttgaagtgtggg
gccgacgtcaacagggtcacctaccagggctactccccgtaccagctcacctggggccgc
ccaagcacccggatacagcagcagctgggccagctgaccctagagaaccttcagatgctg
cccgagagcgaggatgaggagagctatgacacggagtcagagttcacagaggatgagctg
ccctatgatgactgtgtgcttggaggccagcgcctgacgttatga

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