Orcinus orca (killer whale): 101289640
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Entry
101289640 CDS
T05247
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00230
Purine metabolism
oor01100
Metabolic pathways
oor04022
cGMP-PKG signaling pathway
oor04024
cAMP signaling pathway
oor04924
Renin secretion
oor05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101289640 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
101289640 (PDE3A)
04022 cGMP-PKG signaling pathway
101289640 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
101289640 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
101289640 (PDE3A)
Enzymes [BR:
oor01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
101289640 (PDE3A)
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Motif
Pfam:
PDEase_I
TgpA_N
Motif
Other DBs
NCBI-GeneID:
101289640
NCBI-ProteinID:
XP_004270988
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Position
11:16445344..16756416
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AA seq
1131 aa
AA seq
DB search
MAVPGEAARVGAKPGHAEARPAPSSPRGPGCRGCWGALVLRLLRRSQKLSSALCAGSLSF
LLALLVRLVRGEIGCDLERSEEAAAAAEEEEAAPGAEGGVFPGPRGGAPGGGAPLGPWLQ
PSALLFSLLCAFFWMGLYLQRAGVRLPLAVALLAACCGGEALVQIGLGVGEDHLLSLPAA
GVVLSCLAAATWLVLRLRLGVLMIALTSAVRTVALISLERFKVAWRPYLAYLAGVLGILL
ARYVEQILPQSTGAAPREHFGSQLIAGTKEEIPVFKRRRRSSSVVSAEMSGCSSKSHRRT
SLPCIPREQLMGHSEWDHKRGPRGSQSPGTSITVDIAVMGEAHGLITDLLADPSLPPNVC
TSLRAVSNLLSTQLTIQAIHKPRVNPVASFSENYTCSDSEESSEKDKLALPKRLRRSLPP
GLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEAPSSSAINPDSWKNSVMMTLT
KSRSFTSSYAVAASNHVKAKKQNRPGSLVKISPLSSPSSSPLHGTPASSPVSKISAVQFP
ESADATGKQGLSSHRAVTYTQSAPDLSPQILTPPVICSSCGRPYSQGTPADGPLERSGAA
IRTPNRTDDTTQVTSDYETNNNSDSSDIVQNEDETECPREPLRKTSPCSTYTPEAMIFLD
KPILAPEPLVMDNLDSIMEQLNTWNFPIFDLVEKIGRKCGRILSQVSYRLFEDMGLFEAF
KIPVREFMNYFHALEIGYREIPYHNRIHATDVLHAVWYLTTQPIPGLSTVINDHGSASDS
DSDSGFTHGHMGYVFSKMCNVPDDKYGCLSGNIPALELMALYVAAAMHDFDHPGRTNAFL
VATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFRFLVIEAILAT
DLKKHFDFVAKFNAKVNDEVGIDWTNENDRLLVCQMCIKLADINGPAKFKELHLQWTEGI
VNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDSAGLMPGKWVE
DSDESGDTDDPEEEEEEAPNEEETCKNSESPRKKTFKRRKVYCQITQHLLQNHKMWKKVI
EEEQRLAGIEDQSLDQSPQQHPSDQIQAIKEEDEEKGKPRGDETPTPKPNQ
NT seq
3396 nt
NT seq
+upstream
nt +downstream
nt
atggccgtgccgggcgaggccgcccgagtcggggccaagcccggccacgcagaggcgagg
ccggccccctcatcgccccggggcccgggctgccgcggctgctggggcgccctggtgctg
cggctactccggcgctcgcagaaactttcctcggcgctgtgcgcgggctccctgtccttt
ctgctggcgttgctggtgaggctggtccgcggagagattggctgtgacctggagcggagt
gaggaggcggcggcggcggcggaggaggaggaagcggcccccggggcagaagggggcgtc
ttcccggggcctcggggaggtgctcccgggggcggcgcgccgctcggcccctggctgcag
ccctcggcgctgctcttcagtctcctgtgtgccttcttctggatgggcttgtacctccag
cgcgccggggtgcgcctgcctctggccgtcgcgctgctggccgcctgctgcgggggggaa
gcgctcgtccagattgggctgggcgtcggggaggatcacttactctcgctccccgccgcg
ggggtggtgctcagctgcttggccgccgcgacatggctggtactgaggctgaggctgggc
gtcctcatgatcgccttgactagcgcggtcaggaccgtggccctcatttccctagagagg
ttcaaggtcgcctggagaccttacctggcgtacttggccggagtgctggggatcctcctg
gccaggtacgtggagcaaattttgccacagtccacgggggcggctccgagggagcatttc
gggtcccagctgatcgctgggaccaaggaagagatcccggtgtttaagaggaggaggcgg
tccagctccgtggtgtccgccgagatgtcgggctgcagcagcaagtcccatcggaggacc
tccctgccctgcatcccgagggaacagctcatggggcattcagaatgggaccacaaacga
gggccaaggggatcgcagtctccaggaaccagtatcactgtggatattgccgtgatgggc
gaggctcacggtctcatcaccgacctcctggcagacccttctctgccccccaacgtgtgc
acgtccctgagggcagtgagcaaccttctcagcacgcagctcaccatccaggccattcac
aagcccagagtgaaccccgtcgcttccttcagtgaaaactatacctgctctgattctgaa
gaaagctctgaaaaagacaagctggctcttcccaagcgcctgaggaggagtttgccccct
ggtttgctgagacgagtttcatcaacttggacaaccaccacctcagccacgggtctgccc
actttggagcctgccccagtacggagggaccgtagcgccagcatcaaactccatgaagca
ccttcatccagtgctattaatccagattcttggaaaaactcagtgatgatgactctcacc
aaaagcagatcctttacttcatcctatgctgttgctgcctctaaccacgtaaaggctaaa
aagcaaaatcgaccaggttccctagtgaaaatttcacctctttcctcaccctcttcctca
cctctccatgggacccctgccagcagcccagtcagcaaaatttctgcagtgcagtttcca
gaatctgccgatgcaactggcaaacaaggcctaagttctcacagggccgtaacctacact
cagagtgcccctgacctttctcctcagatcctgactccacctgttatatgtagcagctgt
ggcagaccatattcccaagggactcctgctgatgggcccctggagagaagtggggcagcc
attcggacaccaaacagaactgatgacaccactcaagttacctctgattatgaaaccaat
aacaacagtgatagcagtgatattgtacagaacgaagatgagactgaatgccccagagag
cctctgaggaagacatcaccttgcagcacctatactcctgaggccatgatattcctggac
aaaccaattcttgctcctgaacctcttgtcatggataacttggactcaattatggagcag
ctaaatacttggaattttccaatatttgatttggtggagaaaataggaagaaaatgtggc
cgtattcttagtcaggtatcatacagactttttgaagacatgggtctctttgaagctttt
aaaattccagttagggaatttatgaattattttcatgctttggagattggctacagggaa
attccttaccataacagaatccatgccaccgatgtcttacacgctgtttggtatcttacg
acacaacctattcccggcctctcaactgtgattaatgatcacggatcagcaagcgattca
gattctgacagtgggtttacacatggacatatgggatatgtattctcaaaaatgtgtaac
gtgccagatgataaatacggatgtttgtctggaaatatccctgccttggagttgatggcc
ctgtatgtggctgcagccatgcatgattttgatcacccgggaaggactaatgctttcctg
gttgcaactagtgcccctcaggcggtgctctataacgatcgttcagttttggagaaccat
catgcagctgctgcgtggaatcttttcatgtcccggccggaatataacttcttagttaac
cttgaccatgtggaatttaagcatttccgtttccttgtcattgaagcaattttggccact
gacctgaagaaacactttgacttcgtagccaaatttaatgccaaggtgaatgatgaagtt
ggaatagattggaccaatgaaaatgatcgtctgctggtttgtcaaatgtgtataaagttg
gctgatatcaatgggccagctaagtttaaagagctccatcttcagtggacagagggtatc
gtcaatgaattttatgaacagggtgatgaagaggccagcctcgggttaccaataagccct
ttcatggaccgttctgctcctcagttggccaaccttcaggaatccttcatctcgcacatt
gtgggtcctctctgcaactcctatgattcagcaggactgatgccagggaaatgggtggaa
gacagtgatgagtcaggagacaccgatgacccagaagaagaggaggaggaagcaccaaac
gaagaggaaacctgtaaaaatagtgaatctccaagaaagaaaactttcaaaaggagaaaa
gtctactgccaaataactcagcaccttctgcagaaccacaagatgtggaagaaagtcatt
gaggaggaacagaggttggcgggcatagaggatcagtccctggaccagtccccccagcag
catccctcagaccagatccaggccatcaaggaagaagatgaagaaaaggggaagccgaga
ggagacgaaaccccaaccccaaagccaaaccagtga
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