Orcinus orca (killer whale): 101289858
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Entry
101289858 CDS
T05247
Symbol
ADCY4
Name
(RefSeq) adenylate cyclase type 4 isoform X2
KO
K08044
adenylate cyclase 4 [EC:
4.6.1.1
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00230
Purine metabolism
oor01100
Metabolic pathways
oor01522
Endocrine resistance
oor04015
Rap1 signaling pathway
oor04020
Calcium signaling pathway
oor04022
cGMP-PKG signaling pathway
oor04024
cAMP signaling pathway
oor04062
Chemokine signaling pathway
oor04072
Phospholipase D signaling pathway
oor04081
Hormone signaling
oor04082
Neuroactive ligand signaling
oor04114
Oocyte meiosis
oor04211
Longevity regulating pathway
oor04213
Longevity regulating pathway - multiple species
oor04261
Adrenergic signaling in cardiomyocytes
oor04270
Vascular smooth muscle contraction
oor04371
Apelin signaling pathway
oor04540
Gap junction
oor04611
Platelet activation
oor04713
Circadian entrainment
oor04714
Thermogenesis
oor04723
Retrograde endocannabinoid signaling
oor04724
Glutamatergic synapse
oor04725
Cholinergic synapse
oor04727
GABAergic synapse
oor04742
Taste transduction
oor04750
Inflammatory mediator regulation of TRP channels
oor04911
Insulin secretion
oor04912
GnRH signaling pathway
oor04913
Ovarian steroidogenesis
oor04914
Progesterone-mediated oocyte maturation
oor04915
Estrogen signaling pathway
oor04916
Melanogenesis
oor04918
Thyroid hormone synthesis
oor04921
Oxytocin signaling pathway
oor04923
Regulation of lipolysis in adipocytes
oor04925
Aldosterone synthesis and secretion
oor04926
Relaxin signaling pathway
oor04927
Cortisol synthesis and secretion
oor04928
Parathyroid hormone synthesis, secretion and action
oor04934
Cushing syndrome
oor04935
Growth hormone synthesis, secretion and action
oor04970
Salivary secretion
oor04971
Gastric acid secretion
oor04972
Pancreatic secretion
oor04976
Bile secretion
oor05032
Morphine addiction
oor05163
Human cytomegalovirus infection
oor05166
Human T-cell leukemia virus 1 infection
oor05200
Pathways in cancer
oor05207
Chemical carcinogenesis - receptor activation
oor05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101289858 (ADCY4)
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
101289858 (ADCY4)
04371 Apelin signaling pathway
101289858 (ADCY4)
04020 Calcium signaling pathway
101289858 (ADCY4)
04072 Phospholipase D signaling pathway
101289858 (ADCY4)
04024 cAMP signaling pathway
101289858 (ADCY4)
04022 cGMP-PKG signaling pathway
101289858 (ADCY4)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
101289858 (ADCY4)
04081 Hormone signaling
101289858 (ADCY4)
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
101289858 (ADCY4)
09144 Cellular community - eukaryotes
04540 Gap junction
101289858 (ADCY4)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
101289858 (ADCY4)
04062 Chemokine signaling pathway
101289858 (ADCY4)
09152 Endocrine system
04911 Insulin secretion
101289858 (ADCY4)
04923 Regulation of lipolysis in adipocytes
101289858 (ADCY4)
04912 GnRH signaling pathway
101289858 (ADCY4)
04913 Ovarian steroidogenesis
101289858 (ADCY4)
04915 Estrogen signaling pathway
101289858 (ADCY4)
04914 Progesterone-mediated oocyte maturation
101289858 (ADCY4)
04921 Oxytocin signaling pathway
101289858 (ADCY4)
04926 Relaxin signaling pathway
101289858 (ADCY4)
04935 Growth hormone synthesis, secretion and action
101289858 (ADCY4)
04918 Thyroid hormone synthesis
101289858 (ADCY4)
04928 Parathyroid hormone synthesis, secretion and action
101289858 (ADCY4)
04916 Melanogenesis
101289858 (ADCY4)
04925 Aldosterone synthesis and secretion
101289858 (ADCY4)
04927 Cortisol synthesis and secretion
101289858 (ADCY4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
101289858 (ADCY4)
04270 Vascular smooth muscle contraction
101289858 (ADCY4)
09154 Digestive system
04970 Salivary secretion
101289858 (ADCY4)
04971 Gastric acid secretion
101289858 (ADCY4)
04972 Pancreatic secretion
101289858 (ADCY4)
04976 Bile secretion
101289858 (ADCY4)
09156 Nervous system
04724 Glutamatergic synapse
101289858 (ADCY4)
04727 GABAergic synapse
101289858 (ADCY4)
04725 Cholinergic synapse
101289858 (ADCY4)
04723 Retrograde endocannabinoid signaling
101289858 (ADCY4)
09157 Sensory system
04742 Taste transduction
101289858 (ADCY4)
04750 Inflammatory mediator regulation of TRP channels
101289858 (ADCY4)
09149 Aging
04211 Longevity regulating pathway
101289858 (ADCY4)
04213 Longevity regulating pathway - multiple species
101289858 (ADCY4)
09159 Environmental adaptation
04713 Circadian entrainment
101289858 (ADCY4)
04714 Thermogenesis
101289858 (ADCY4)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101289858 (ADCY4)
05207 Chemical carcinogenesis - receptor activation
101289858 (ADCY4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
101289858 (ADCY4)
05163 Human cytomegalovirus infection
101289858 (ADCY4)
09165 Substance dependence
05032 Morphine addiction
101289858 (ADCY4)
09166 Cardiovascular disease
05414 Dilated cardiomyopathy
101289858 (ADCY4)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
101289858 (ADCY4)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
101289858 (ADCY4)
Enzymes [BR:
oor01000
]
4. Lyases
4.6 Phosphorus-oxygen lyases
4.6.1 Phosphorus-oxygen lyases (only sub-subclass identified to date)
4.6.1.1 adenylate cyclase
101289858 (ADCY4)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Guanylate_cyc
Adcy_cons_dom
AC_N
CD52
Motif
Other DBs
NCBI-GeneID:
101289858
NCBI-ProteinID:
XP_033267462
LinkDB
All DBs
Position
2:complement(128092338..128131120)
Genome browser
AA seq
1013 aa
AA seq
DB search
MLCGLGGFSLLLGLASREQRLQRWTRPLSGLVWAALLALGLGFLFTGGVVSAWDQVSFFL
FVIFTVYAMLPLGMRDAAAAGLASSLSHLLVLGLYLGLQPDSQPALLPQLAANAVLFLCG
NVAGAYHKALMERALRATFREALSSLHSRRRLDTEKKHQEHLLLSILPAYLAREMKAEIM
ARLQAGQGSRPESTNNFHSLYVKRHQGVSVLYADIVGFTRLASECSPKELVLMLNELFGK
FDQIAKEHECMRIKILGDCYYCVSGLPLSLPDHAINCVRMGLDMCRAIRKLRAATGVDIN
MRVGVHSGSVLCGVIGLQKWQYDVWSHDVTLANHMEASGVPGRVHITGATLALLAGAYAV
EDAAMEHGDPYLRELGEPTYLVIDPRAEEEDEKGTAGRLLSSLEGPKMRPSLLMTRYLES
WGAAKPFAHLSHVESPVSTSTPLPEKALSSFSPQWSLDRSRTPRGLDDELDTGDAKFFQV
IEQLNSQKQWKQSEDFNPLTLYFREKEMEKEYRLSALPAFKYYAACTFLVFFSNFIIQML
VTNRPPALTITYSITFLLFFLLLFVCFSEHLTKCVLKGPKMLHWLPTLSVLVATRPGLRV
ALGTATILLVFSMAITSLVFLPAASNCPFRAPNVSFTASNLSWELPGSLPLISVPYSVHC
CVLGFLSCSLFLHMSFELKLLLLLLWLAACCSLFLHSHAWLSDCLIARLYLGALDSRPGV
LKEPKLMGAIFFFIFFFTLLVLARQNEYYCRLDFLWKKKLRQEQEETETMENLTRLLLEN
VLPAHVAPQFIGQNRRNEDLYHQSYECVCVLFASVPDFKEFYSESSINHEGLECLRLLNE
IIADFDELLSKPKFSGVEKIKTICSTYMAATGLNATSGQDAQQDAEQSCSHLGTMVEFAV
ALGSKLDVINKHSFNNFRLRVGLNHGPVVAGVIGAQKPQYDIWGNTVNVASRMESTGVLG
KIQVTEETARALQSLGYTCYSRGIIKVKGKGQLCTYFLNTDLTRTGPPSATLG
NT seq
3042 nt
NT seq
+upstream
nt +downstream
nt
atgctgtgcgggctgggcggcttctcgctgctgctgggcctggcttcccgcgagcagcga
ctgcagcgctggacgcgtcccctgtcgggcctcgtgtgggcagcgctgctcgcgctaggc
ctcggcttcctcttcaccgggggcgtggtgagcgcctgggaccaggtgtcctttttcctt
tttgtcatcttcaccgtgtacgccatgttgcccttgggcatgcgggacgccgccgccgcg
ggtctcgcctcttcactctcacacctgctggtcctcgggctgtatcttgggcttcagccg
gactcacagcccgcgctgctgccgcagctggcggcaaacgcggtgttgttcctgtgcggg
aacgtggccggagcataccacaaggcgctgatggagcgcgcgctgcgcgccacgttccgg
gaggcgcttagttccctgcactcccgccggagactcgacaccgagaagaagcaccaggaa
caccttctcttgtccatccttcctgcctacctggcccgagagatgaaggcggagatcatg
gcacggctgcaggctggacaggggtcacggccagagagcaccaacaacttccacagcctc
tatgtcaagaggcaccagggagtaagcgtgctgtatgctgacatcgtgggcttcacgcgg
ctggccagtgagtgctcccctaaggagttggtgctcatgctaaacgagctctttggcaag
ttcgaccagatcgccaaggagcatgaatgcatgcggatcaagatcctgggagactgttac
tactgtgtctccgggctgccactctcgctgccagaccacgccatcaactgcgtgcgcatg
gggctggacatgtgccgggccatcaggaaacttcgggcagccaccggcgtggatatcaac
atgcgtgtgggtgtgcactcgggcagcgtgctctgcggggtcatcgggctgcagaagtgg
cagtatgatgtctggtcccatgatgtcactctggccaaccacatggaggcgagtggagtg
ccaggacgagtacatatcacaggggctacgctggcactgctggcaggggcttatgctgtg
gaggatgcagccatggaacacggggacccataccttcgggagctaggggagccgacctac
cttgtcatcgatccccgggctgaggaggaggacgagaagggcactgcaggcaggttgctg
tcctctcttgagggccccaagatgcgtccgtcactgctgatgacccgctacctggagtcc
tggggtgcggccaagccttttgcccacctgagccacgtggagagccccgtgtccacctct
acccctctgccggagaaggccctgtcttccttcagcccccagtggagcctggaccggagc
cgtaccccccggggactagatgatgaactagacaccggggatgccaagttcttccaagtc
attgaacagctcaactctcagaaacagtggaaacagtcagaggacttcaacccattgaca
ctgtacttccgagagaaggagatggagaaagagtatcggctctctgcactccccgccttc
aaatactatgccgcctgcaccttcctggtttttttctccaacttcattatccagatgctg
gtgacaaacaggcccccagctctgaccatcacctatagcatcaccttcctcctcttcttc
ctcctcctcttcgtctgcttctcagagcacctgacgaagtgtgtcttgaaaggccccaag
atgctgcactggctgcccacactgtctgtcctagtggccacacggcccggactgcgagtt
gccctgggcaccgctaccatcctgctcgtcttctccatggccattaccagcctggtcttc
ttaccggcagcatcaaactgccctttccgggctcccaatgtgtccttcacggcttccaac
ctctcctgggagctccctgggtccctgcctctcatcagcgtcccctactccgtgcactgc
tgcgtgctggggttcctctcctgctccctcttcctgcacatgagcttcgagctgaagctg
ctgctgctgctgctgtggctggcagcctgctgctccctcttcctgcactcccacgcctgg
ctgtctgactgtctcatcgcccgcctctatctgggtgccttggactccaggccaggggtg
ctgaaggagcctaaactgatgggagcaatcttcttcttcatcttcttcttcaccctcctg
gtcctggctcggcagaatgagtattactgccgcctggacttcctgtggaagaagaagctg
aggcaagagcaggaggagacagagacgatggaaaacctgactcggctgctcttggagaat
gtgctccccgcgcacgtagccccccagttcatcggccagaatcggcgcaacgaggacctc
taccaccagtcctacgagtgtgtgtgtgtcctcttcgcctcagtcccagacttcaaggag
ttttactctgaatccagcatcaaccatgaggggctagagtgtctgcggctgctcaatgag
ataattgctgattttgatgagctgctctccaagcctaagttcagtggggtggagaaaatc
aaaactatctgcagcacctacatggcagctacaggcttgaacgccacctctggacaggac
gcacagcaggatgccgagcaaagctgcagccaccttggcaccatggtagagtttgccgtg
gcccttgggtctaagctggacgtcatcaacaagcactcattcaacaacttccgcttgcgt
gtggggttaaaccacggacctgtagtggccggagtgattggggcccagaaaccacaatat
gacatctggggcaacacggtgaacgtggccagccgaatggagagcacaggcgtcctgggc
aagatccaagtgaccgaagagacagcccgcgccctgcagtccttaggctacacctgctac
agccggggcatcatcaaggtcaaaggcaaagggcagctctgcacctacttcctgaacaca
gatttgacacgaactggacctccctcggccaccctaggctga
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