KEGG   Orcinus orca (killer whale): 101289923
Entry
101289923         CDS       T05247                                 
Symbol
MGST3
Name
(RefSeq) microsomal glutathione S-transferase 3
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
oor  Orcinus orca (killer whale)
Pathway
oor00480  Glutathione metabolism
oor00980  Metabolism of xenobiotics by cytochrome P450
oor00982  Drug metabolism - cytochrome P450
oor00983  Drug metabolism - other enzymes
oor01100  Metabolic pathways
oor01524  Platinum drug resistance
oor05200  Pathways in cancer
oor05204  Chemical carcinogenesis - DNA adducts
oor05207  Chemical carcinogenesis - receptor activation
oor05208  Chemical carcinogenesis - reactive oxygen species
oor05225  Hepatocellular carcinoma
oor05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oor00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    101289923 (MGST3)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    101289923 (MGST3)
   00982 Drug metabolism - cytochrome P450
    101289923 (MGST3)
   00983 Drug metabolism - other enzymes
    101289923 (MGST3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101289923 (MGST3)
   05204 Chemical carcinogenesis - DNA adducts
    101289923 (MGST3)
   05207 Chemical carcinogenesis - receptor activation
    101289923 (MGST3)
   05208 Chemical carcinogenesis - reactive oxygen species
    101289923 (MGST3)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101289923 (MGST3)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    101289923 (MGST3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    101289923 (MGST3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:oor02000]
    101289923 (MGST3)
Enzymes [BR:oor01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     101289923 (MGST3)
Transporters [BR:oor02000]
 Other transporters
  Pores ion channels [TC:1]
   101289923 (MGST3)
SSDB
Motif
Pfam: MAPEG Bax1-I
Other DBs
NCBI-GeneID: 101289923
NCBI-ProteinID: XP_004282094
LinkDB
Position
1:complement(91409888..91428211)
AA seq 152 aa
MAVLSKEYGFVILTGAASFLMVTHLAINVSKARKKYKVEYPTMYSTDPENGHLFNCIQRA
HQNTLEVYPPFLFFLAVGGVYHPRVVSGLGLAWIVGRVLYAYGYYTGEPRKRKRGALSFI
ALIGLMGTSVCSAFQHLGWVRTGLSSGCKSCH
NT seq 459 nt   +upstreamnt  +downstreamnt
atggccgtcctctctaaggaatatggtttcgtgattctaactggtgctgccagcttccta
atggtaactcatctagccatcaacgtttccaaggcccgcaagaagtacaaagtggagtat
cctacaatgtatagcactgaccctgaaaacggacacctcttcaactgcattcagcgggcc
caccagaacacgttggaagtgtaccctcccttcttattttttctagctgtcggaggtgtt
taccacccacgtgtagtttctggcttgggcttggcctggattgttggacgagttctttat
gcttatggctattacacaggagaacctagaaagcggaaacggggagccctgagcttcatc
gccctcattggcctgatgggcacctctgtgtgctctgctttccagcatcttggttgggtt
agaactggcttgagcagtgggtgcaaaagctgccattaa

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