Orcinus orca (killer whale): 101290156
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Entry
101290156 CDS
T05247
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial isoform X1
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor00020
Citrate cycle (TCA cycle)
oor00480
Glutathione metabolism
oor01100
Metabolic pathways
oor01200
Carbon metabolism
oor01210
2-Oxocarboxylic acid metabolism
oor01230
Biosynthesis of amino acids
oor04146
Peroxisome
oor05230
Central carbon metabolism in cancer
Module
oor_M00009
Citrate cycle (TCA cycle, Krebs cycle)
oor_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
101290156 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
101290156 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
101290156 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
101290156 (IDH2)
Enzymes [BR:
oor01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
101290156 (IDH2)
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
101290156
NCBI-ProteinID:
XP_004278310
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All DBs
Position
2:61969027..61986160
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AA seq
452 aa
AA seq
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MSGYLRVVRLLCRASGSGPAWVPAALTAPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICRNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKIVFTPKDGSGAKEWEVYSFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYKTEFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLICPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKSNLDKALGQQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgtctggttacctgcgggttgtacgcttgctctgtagagcctccggttccgggccggcc
tgggtgccggcagccttaacagcccccaacttgcaagagcagccgcggcgccactatgcc
gacaagaggatcaaggtggcgaagccagtggtggagatggacggcgatgagatgacccgt
attatctggcagttcatcaaggagaagctcatcctgccccatgtggacgtccagctcaag
tattttgacctggggctcccaaaccgtgaccagaccaatgatcaggtcaccatcgactcc
gcgctggccacccagaagtacagcgtggctgtcaagtgtgccaccatcacccctgacgag
gcccgtgtggaagagttcaagctgaagaagatgtggaagagtcccaatggaaccatccgg
aacatcctcggggggactgtcttccgggagcccatcatctgcagaaacatcccacgcctc
gtccctggctggaccaagcccatcaccattggcaggcacgcccacggcgaccagtacaag
gccacagactttgtggctgaccgggccggcacattcaagatcgtcttcaccccaaaggac
ggcagcggagctaaggagtgggaggtgtacagcttccccgccggtggcgtgggcatgggc
atgtacaacacggatgagtccatctcgggttttgcgcacagctgcttccagtatgccatc
cagaagaagtggccactctacatgagcaccaagaacaccattctgaaagcctatgacggg
cgcttcaaggacatcttccaggagatctttgagaagcactacaagaccgagttcgacaag
aataagatctggtacgagcaccgcctcattgacgacatggtggctcaggtcctcaagtct
tcgggcggctttgtgtgggcctgcaagaactacgacggagacgtgcaatcagacatcctg
gcccagggctttggctcccttggcctgatgacgtccgtgctgatctgcccggatgggaag
accattgaggctgaggctgctcatgggacggtcacgcgccactatcgggagcaccagaag
ggccggcctaccagcaccaaccctatcgccagcatctttgcctggacgcgtggcctggag
caccgggggaagttggatggaaaccaggacctgatcaggtttgcccagaccctggagaag
gtgtgcgtcgagacagtggagagtggagccatgaccaaggacctggcgggctgcatccat
ggcctcagcaatgtgaagctgaacgagcacttcctgaacacctcggacttcctggacacc
atcaagagcaacctggacaaagctctgggccagcagtag
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