Orcinus orca (killer whale): 101290315
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Entry
101290315 CDS
T05247
Symbol
TBK1
Name
(RefSeq) serine/threonine-protein kinase TBK1
KO
K05410
TANK-binding kinase 1 [EC:
2.7.11.10
]
Organism
oor
Orcinus orca (killer whale)
Pathway
oor04014
Ras signaling pathway
oor04137
Mitophagy - animal
oor04140
Autophagy - animal
oor04620
Toll-like receptor signaling pathway
oor04621
NOD-like receptor signaling pathway
oor04622
RIG-I-like receptor signaling pathway
oor04623
Cytosolic DNA-sensing pathway
oor04657
IL-17 signaling pathway
oor04936
Alcoholic liver disease
oor05014
Amyotrophic lateral sclerosis
oor05022
Pathways of neurodegeneration - multiple diseases
oor05135
Yersinia infection
oor05160
Hepatitis C
oor05161
Hepatitis B
oor05162
Measles
oor05163
Human cytomegalovirus infection
oor05164
Influenza A
oor05165
Human papillomavirus infection
oor05167
Kaposi sarcoma-associated herpesvirus infection
oor05168
Herpes simplex virus 1 infection
oor05169
Epstein-Barr virus infection
oor05170
Human immunodeficiency virus 1 infection
oor05171
Coronavirus disease - COVID-19
oor05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oor00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
101290315 (TBK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101290315 (TBK1)
04137 Mitophagy - animal
101290315 (TBK1)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
101290315 (TBK1)
04621 NOD-like receptor signaling pathway
101290315 (TBK1)
04622 RIG-I-like receptor signaling pathway
101290315 (TBK1)
04623 Cytosolic DNA-sensing pathway
101290315 (TBK1)
04657 IL-17 signaling pathway
101290315 (TBK1)
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101290315 (TBK1)
05161 Hepatitis B
101290315 (TBK1)
05160 Hepatitis C
101290315 (TBK1)
05171 Coronavirus disease - COVID-19
101290315 (TBK1)
05164 Influenza A
101290315 (TBK1)
05162 Measles
101290315 (TBK1)
05168 Herpes simplex virus 1 infection
101290315 (TBK1)
05163 Human cytomegalovirus infection
101290315 (TBK1)
05167 Kaposi sarcoma-associated herpesvirus infection
101290315 (TBK1)
05169 Epstein-Barr virus infection
101290315 (TBK1)
05165 Human papillomavirus infection
101290315 (TBK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
101290315 (TBK1)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
101290315 (TBK1)
05022 Pathways of neurodegeneration - multiple diseases
101290315 (TBK1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101290315 (TBK1)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
101290315 (TBK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oor01001
]
101290315 (TBK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
oor04131
]
101290315 (TBK1)
Enzymes [BR:
oor01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
101290315 (TBK1)
Protein kinases [BR:
oor01001
]
Serine/threonine kinases: Other
IKK family [OT]
101290315 (TBK1)
Membrane trafficking [BR:
oor04131
]
Autophagy
Xenophagy
Other xenophagy associated proteins
101290315 (TBK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
Pkinase_fungal
ABC1
Kinase-like
DUF713
CEP63
COG6_N
Motif
Other DBs
NCBI-GeneID:
101290315
NCBI-ProteinID:
XP_004276639
LinkDB
All DBs
Position
11:51151123..51190552
Genome browser
AA seq
729 aa
AA seq
DB search
MQSTSNHLWLLSDILGQGATANVFRGRHKKTGDLFAIKVFNNISFLRPVDVQMREFEVLK
KLNHKNIVKLFAIEEEVTTRHKVLIMEFCPCGSLYTVLEEPCNAYGLPESEFLIVLRDVV
GGMNHLRENGIVHRDIKPGNIMRVIGEDGQSVYKLTDFGAARELEDDEQFVSLYGTEEYL
HPDMYERAVLRKDHQKKYGATVDLWSIGVTFYHAATGSLPFRPFEGPRRNKEVMYKIITG
KPSGAISGVQKAENGPIDWSGDMPVSCSLSRGLQVLLTPVLANILEADQEKCWGFDQFFA
ETSDILHRMIIHVFSLQQMTAHKIYIHSYNTATVFHELVYKQTKIISSNQELIYEGRRLV
LEPGRLAQHFPKTADENPIFVVSREPLSTIGLIYEKISLPKVHPRYDLDGDASMAKAVTG
VVCYACRIASTLLLYQELMRKGIRWLIELVKDDYNETVHKKTEVVITLDFCIRNIEKTVK
VYEKLMKINLEAAELGEISDIHTKLLRLSSSQGTIETSLQDIESKLSPGGLLADTWTHQE
GTHPKDRHVEKLQVLLNCITEIYYQFKKDKAERRLAYNEEQIHKFDKQKLYYHATKAMTH
FTDECVKKYEAFLDKSEEWMRKMLHLRKQLLSLTNQCFDIEEEVSKYQDYTNELQETLPQ
KMFAASSGIKHTMTPIYPCSNTLVEMTLGMKKLKEEMEGVVKELAENNHILERFGSLTMD
GGLRNVDCL
NT seq
2190 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcacttctaatcatttgtggcttttatctgatattttaggccaaggagctact
gcaaatgtctttcgtggaagacataagaaaactggtgacttatttgctatcaaagtattt
aataacataagctttcttcgtccagtggatgttcaaatgagagaatttgaagtgttaaaa
aaactcaatcacaaaaatattgtcaaattatttgctattgaagaggaggtaacaacgaga
cataaagtacttattatggaattttgtccatgtggaagtttatacactgttttagaagaa
ccatgtaatgcctatggactaccagagtctgaatttttaattgttttgcgagatgtggtg
ggtggaatgaatcatctccgagaaaatggcatagttcaccgtgatattaagccaggaaat
atcatgcgtgtaataggggaagacggacagtctgtgtacaaactcacagattttggtgca
gctagagaattagaagatgatgagcagtttgtttctctgtatggcacagaagaatatttg
catcctgatatgtatgagagagcagtgctgagaaaagatcatcagaagaaatatggagcg
actgttgatctttggagcattggagtaacattttaccatgcagctactggatcactgcca
tttagaccgtttgaagggccgcgtaggaataaggaagtgatgtataaaataattactgga
aagccttctggtgcaatatctggagtacagaaagcagaaaatggaccaattgactggagt
ggagacatgcccgtttcttgtagtctttctcggggtcttcaagttctacttacccctgtt
cttgcaaacatccttgaggcagatcaggaaaagtgttggggttttgaccagttttttgca
gaaacaagtgatatacttcaccggatgataattcatgttttttcgctacaacaaatgaca
gctcataaaatttatattcatagctataatactgctactgtatttcatgaactggtgtat
aaacaaaccaaaattatttcttcaaatcaagaacttatatatgaaggacgacgtttagtt
ctagaacctggaagactggcacaacatttccctaaaactgctgatgaaaatcccatcttt
gtagtaagccgggaacctctgagtacaataggattgatatatgaaaaaatttccctccct
aaagtacatccacgttatgatttagatggggatgccagcatggctaaggcagtaacagga
gttgtgtgttatgcctgtagaattgccagtaccttgctgctttatcaggaattaatgcga
aaggggatacgatggttgatagaattagttaaagatgattataatgaaactgttcacaaa
aagacggaagttgtgatcacattagatttctgcatcagaaacattgaaaagactgtgaaa
gtatatgaaaagttgatgaagatcaacctagaagcagcagagttaggtgaaatttcagac
atacacaccaaactgttgagactttccagttctcagggaacaatagaaaccagtcttcag
gatattgaaagcaaattatctccaggtggattgctggcagatacatggacccatcaagaa
ggcactcatccaaaagatagacatgtagaaaagctacaagtcctgttaaattgcattaca
gagatttactatcagttcaaaaaagacaaagcagaacgtagactagcttataatgaagaa
caaatccacaaatttgataagcaaaaactgtattatcatgcaacaaaagctatgacccac
tttacagatgaatgtgttaaaaagtatgaggcttttctggataagtcagaagaatggatg
agaaagatgcttcatcttaggaaacagttattatccctaactaatcagtgttttgatatt
gaagaagaagtatcaaagtatcaagactatactaatgagttacaagaaactttgccacag
aaaatgtttgcagcctccagtggaatcaaacataccatgaccccaatttatccatgttct
aacacattagtagaaatgactcttggtatgaagaaattaaaggaagaaatggaaggggta
gttaaagaacttgctgaaaataatcatattttagaaaggtttggctctttaaccatggat
ggtggccttcgcaatgttgactgtctatag
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