KEGG   Odobenus rosmarus divergens (Pacific walrus): 101363525
Entry
101363525         CDS       T05148                                 
Symbol
NRAS
Name
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04012  ErbB signaling pathway
oro04014  Ras signaling pathway
oro04015  Rap1 signaling pathway
oro04062  Chemokine signaling pathway
oro04068  FoxO signaling pathway
oro04071  Sphingolipid signaling pathway
oro04072  Phospholipase D signaling pathway
oro04137  Mitophagy - animal
oro04140  Autophagy - animal
oro04150  mTOR signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04210  Apoptosis
oro04211  Longevity regulating pathway
oro04213  Longevity regulating pathway - multiple species
oro04218  Cellular senescence
oro04360  Axon guidance
oro04370  VEGF signaling pathway
oro04371  Apelin signaling pathway
oro04540  Gap junction
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04625  C-type lectin receptor signaling pathway
oro04650  Natural killer cell mediated cytotoxicity
oro04660  T cell receptor signaling pathway
oro04662  B cell receptor signaling pathway
oro04664  Fc epsilon RI signaling pathway
oro04714  Thermogenesis
oro04720  Long-term potentiation
oro04722  Neurotrophin signaling pathway
oro04725  Cholinergic synapse
oro04726  Serotonergic synapse
oro04730  Long-term depression
oro04810  Regulation of actin cytoskeleton
oro04910  Insulin signaling pathway
oro04912  GnRH signaling pathway
oro04915  Estrogen signaling pathway
oro04916  Melanogenesis
oro04917  Prolactin signaling pathway
oro04919  Thyroid hormone signaling pathway
oro04921  Oxytocin signaling pathway
oro04926  Relaxin signaling pathway
oro04929  GnRH secretion
oro04933  AGE-RAGE signaling pathway in diabetic complications
oro04935  Growth hormone synthesis, secretion and action
oro05010  Alzheimer disease
oro05022  Pathways of neurodegeneration - multiple diseases
oro05034  Alcoholism
oro05160  Hepatitis C
oro05161  Hepatitis B
oro05163  Human cytomegalovirus infection
oro05165  Human papillomavirus infection
oro05166  Human T-cell leukemia virus 1 infection
oro05167  Kaposi sarcoma-associated herpesvirus infection
oro05170  Human immunodeficiency virus 1 infection
oro05200  Pathways in cancer
oro05203  Viral carcinogenesis
oro05205  Proteoglycans in cancer
oro05206  MicroRNAs in cancer
oro05207  Chemical carcinogenesis - receptor activation
oro05208  Chemical carcinogenesis - reactive oxygen species
oro05210  Colorectal cancer
oro05211  Renal cell carcinoma
oro05213  Endometrial cancer
oro05214  Glioma
oro05215  Prostate cancer
oro05216  Thyroid cancer
oro05218  Melanoma
oro05219  Bladder cancer
oro05220  Chronic myeloid leukemia
oro05221  Acute myeloid leukemia
oro05223  Non-small cell lung cancer
oro05224  Breast cancer
oro05225  Hepatocellular carcinoma
oro05226  Gastric cancer
oro05230  Central carbon metabolism in cancer
oro05231  Choline metabolism in cancer
oro05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
oro05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101363525 (NRAS)
   04012 ErbB signaling pathway
    101363525 (NRAS)
   04014 Ras signaling pathway
    101363525 (NRAS)
   04015 Rap1 signaling pathway
    101363525 (NRAS)
   04370 VEGF signaling pathway
    101363525 (NRAS)
   04371 Apelin signaling pathway
    101363525 (NRAS)
   04068 FoxO signaling pathway
    101363525 (NRAS)
   04072 Phospholipase D signaling pathway
    101363525 (NRAS)
   04071 Sphingolipid signaling pathway
    101363525 (NRAS)
   04151 PI3K-Akt signaling pathway
    101363525 (NRAS)
   04150 mTOR signaling pathway
    101363525 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101363525 (NRAS)
   04137 Mitophagy - animal
    101363525 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    101363525 (NRAS)
   04218 Cellular senescence
    101363525 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    101363525 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    101363525 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    101363525 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    101363525 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    101363525 (NRAS)
   04660 T cell receptor signaling pathway
    101363525 (NRAS)
   04662 B cell receptor signaling pathway
    101363525 (NRAS)
   04664 Fc epsilon RI signaling pathway
    101363525 (NRAS)
   04062 Chemokine signaling pathway
    101363525 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    101363525 (NRAS)
   04929 GnRH secretion
    101363525 (NRAS)
   04912 GnRH signaling pathway
    101363525 (NRAS)
   04915 Estrogen signaling pathway
    101363525 (NRAS)
   04917 Prolactin signaling pathway
    101363525 (NRAS)
   04921 Oxytocin signaling pathway
    101363525 (NRAS)
   04926 Relaxin signaling pathway
    101363525 (NRAS)
   04935 Growth hormone synthesis, secretion and action
    101363525 (NRAS)
   04919 Thyroid hormone signaling pathway
    101363525 (NRAS)
   04916 Melanogenesis
    101363525 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    101363525 (NRAS)
   04726 Serotonergic synapse
    101363525 (NRAS)
   04720 Long-term potentiation
    101363525 (NRAS)
   04730 Long-term depression
    101363525 (NRAS)
   04722 Neurotrophin signaling pathway
    101363525 (NRAS)
  09158 Development and regeneration
   04360 Axon guidance
    101363525 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    101363525 (NRAS)
   04213 Longevity regulating pathway - multiple species
    101363525 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    101363525 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101363525 (NRAS)
   05206 MicroRNAs in cancer
    101363525 (NRAS)
   05205 Proteoglycans in cancer
    101363525 (NRAS)
   05207 Chemical carcinogenesis - receptor activation
    101363525 (NRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    101363525 (NRAS)
   05203 Viral carcinogenesis
    101363525 (NRAS)
   05230 Central carbon metabolism in cancer
    101363525 (NRAS)
   05231 Choline metabolism in cancer
    101363525 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101363525 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    101363525 (NRAS)
   05225 Hepatocellular carcinoma
    101363525 (NRAS)
   05226 Gastric cancer
    101363525 (NRAS)
   05214 Glioma
    101363525 (NRAS)
   05216 Thyroid cancer
    101363525 (NRAS)
   05221 Acute myeloid leukemia
    101363525 (NRAS)
   05220 Chronic myeloid leukemia
    101363525 (NRAS)
   05218 Melanoma
    101363525 (NRAS)
   05211 Renal cell carcinoma
    101363525 (NRAS)
   05219 Bladder cancer
    101363525 (NRAS)
   05215 Prostate cancer
    101363525 (NRAS)
   05213 Endometrial cancer
    101363525 (NRAS)
   05224 Breast cancer
    101363525 (NRAS)
   05223 Non-small cell lung cancer
    101363525 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101363525 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    101363525 (NRAS)
   05161 Hepatitis B
    101363525 (NRAS)
   05160 Hepatitis C
    101363525 (NRAS)
   05163 Human cytomegalovirus infection
    101363525 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    101363525 (NRAS)
   05165 Human papillomavirus infection
    101363525 (NRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    101363525 (NRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    101363525 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    101363525 (NRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101363525 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    101363525 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101363525 (NRAS)
   01522 Endocrine resistance
    101363525 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:oro04131]
    101363525 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:oro04147]
    101363525 (NRAS)
   04031 GTP-binding proteins [BR:oro04031]
    101363525 (NRAS)
Membrane trafficking [BR:oro04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    101363525 (NRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    101363525 (NRAS)
Exosome [BR:oro04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   101363525 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   101363525 (NRAS)
  Exosomal proteins of breast cancer cells
   101363525 (NRAS)
  Exosomal proteins of colorectal cancer cells
   101363525 (NRAS)
GTP-binding proteins [BR:oro04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    101363525 (NRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N Septin Ldh_1_N
Other DBs
NCBI-GeneID: 101363525
NCBI-ProteinID: XP_012418140
LinkDB
Position
Unknown
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSNDDGTQG
CMGLPCVVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgactgagtacaaactggtggtggttggagcaggtggtgtcgggaaaagcgcattgaca
atccagctaatccagaaccactttgtagatgagtatgatcccaccatagaggattcttac
cgaaaacaggtggttatagacggtgaaacctgtctgttggacatactggatacagctggt
caagaggagtacagtgccatgagagaccaatacatgaggacaggcgaaggcttcctctgt
gtatttgccatcaataatagcaaatcatttgcagatattaacctctacagggaacagatt
aagcgcgtaaaagattcagatgatgtacctatggtgctagtaggaaataagtgtgatttg
ccaacaaggacagtggacacaaaacaagcccacgaactggccaagagttatgggattcca
ttcattgaaacctcagccaagaccagacagggtgtcgaagatgccttttacacactggta
agagaaatacgtcagtaccgaatgaagaaactcaacagcaatgatgatgggactcaaggt
tgtatggggttaccgtgtgtggtgatgtaa

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