Odobenus rosmarus divergens (Pacific walrus): 101365447
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Entry
101365447 CDS
T05148
Symbol
SETX
Name
(RefSeq) probable helicase senataxin isoform X1
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
oro
Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
oro00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
101365447 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
oro03021
]
101365447 (SETX)
Enzymes [BR:
oro01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
101365447 (SETX)
5.6.2.5 RNA 5'-3' helicase
101365447 (SETX)
Transcription machinery [BR:
oro03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
101365447 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
nSTAND3
AAA_22
ResIII
SLFN-g3_helicase
NAT10_TcmA_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
101365447
NCBI-ProteinID:
XP_012418479
LinkDB
All DBs
Position
Unknown
AA seq
2696 aa
AA seq
DB search
MLQRRCRMSTCCWCTPGGISTVDFLQRYASETHSSEFQTADEDLCYCLECVAEYHKARDD
LPFLHEVLWELETLRLINYFEKSMKAEIGDDDELYIVDNNGEAQLFDFTGQDFENKLRVP
LLEILKYPYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAIL
TARNLGKVDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTN
YKNYWLGICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQADDDSVDPFWPALHCF
MVILDRLGSKVWGQRIDPIEAFQTIINNVSYNKEIQNIRNSSVRTKLEPESYSDDATCSQ
IVYNYNPEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPF
VQSLMDLKDLGVAYIVEVIHHLHSEVKDVLNQTDAMCDKVTEFFLLILVSVIELHRNKKC
LHLLWVSSQQWVEAVVKCAKLPTTAFARSSEKSSGNCSKGTAMISSLSLHSMPSNSVQLA
CVQLIRSLLKEGYQLGQQTLCKRFWDKLNLFLRGNLSLGWQLTTQETHELQTCLKQIIKN
IKVKVPQCNTFVDLSPAGKSSPASYSKEESEQIERRSNKDLHCLENSSPTFSKEPMKAEA
YQIQENILIKASNTIEEDNEQNYIKDWKLEDHLSAESCIKKSSKNVFTERAQDQVKISTG
KQKSVKENCTSRNVLQNCTSRNGPERGCDRGIIMSTRLLTDSSTDSLEKACTSNEDLSFK
DDALGKTSKSKTKAHKDEICAKLSHVIKKQHRKSTLINNTGNLEENLTVSNIDSFYSRKD
SGGQKGDGFMHNLSLDPLGILDEKNGEQKSQNSLLLKKKQLKSEELDIFSSHENSYQIQE
CHIDDKDLVSFTEVTNTFVRKTSPFKDPVTVLESKDKEISKNTSQMSSHLREQAPGLSPQ
SDTLTDSQIDRDLHKLSLIAQASVIKFPSDSTQKSSSQLQRRVKDDRRCFPADQNNTGEA
CRGQIIIISDSDDDDEGILGFEKHIKQDKIGIKKECPEQHTSIASTNVEKKLIKEEETKS
LLQFEESDSQFFEFESPCEVFSVWQDQEPDKNSVQESEKNSCSTDIADITNDWGYETDYV
SEEVIKKVAEGIEKHTEPQSSISVGEFCEIEVKKRKRKRFEKPMAEGPLRPSPSGRNENQ
PDILNERGLTENDFKSMDLRTVSPSSSVQRDKDTTVSLKKSSPKLHTYSKPIRRVPLSKT
PKKTHSDTKKGQNKSSNYISCRTTPAIVPPKKFRQCPEPTLTVEKLGLKKAPRRAFELSQ
RSLESLVKLRHHGKTVGVVDTSKKTKLISPQTLSVRNNKKLLTSQDLQLRRQMRPKSQQN
RQGLLDYENKDTTRAGLCTAQNSDIPVPESDGSDYSYKGGTEVVANNTGKQIKRVSSEPE
PVKTKYVSQVTNDACLLNQSAAVVLNGRIPTNEIIVSASADPLGGGDRTVHHLELATLKD
GEPESNSDTEDENIFLTQHDPEDMDLCSQMENGNEKLIEVVHGKDTAQVEEDSVSQPQLE
SWSSTKCKYKDCVETPKNQGDYCSKHCEAKAADEDVFRKPGLPLSASKPSRPSTAKIFSS
SSTSRIANLSKSLESTSALPPALKNKSNGAQAVLKVPQPASLVSPKPVGEVKSLGNVFHP
QTPSNCSRQGYKLTFGESKSFSASSPVHILLSSQSISDTFVKEVLKWKYEMFVNFDQCGP
PASLCQSISRPVPVRFQDCGDYFNVFFPLMILNTFETVAQEWISSPNKEKFYQLHLRKFP
ADYKKYWEFVVHLEECELAKQVHPKENDLVFLVPERQNGEKKDTERNRMQDLREYHCGYI
HKFRRTSVMRSGKSECSLSIQTQDNLPVNLNELVKCVVISSLVTTQRKLKAMSLLSGRNQ
LARAVLNPNPMDFCTKDLLTTTSERIIAYLRDFNEDQKKAIETAYAMVKHSPSVAKICLI
HGPPGTGKSKTIVGLLYRLLTENQRKGHSDENSNAKIKQNRVLVCAPSNAAVDELMKKII
LEFKEKCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPSHVQEMH
RRKEFLDHQLDELSRQRALCRGGREIQRQELDEKIAKVSKERQELASKIKEVQGRPQKTQ
SIIILESHVICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNK
LILVGDPKQLPPTVISMKAQEYGYDQSMMARFYKLLEDNVEHNMIGRLPILQLTVQYRMH
PDICLFPSNYVYNRSLKTNRQTETNRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIK
LVMEIIKLIKDKRRDVTFRNIGIITHYKAQKTMIQKDLDKEFDKKGPAEVDTVDGFQGRQ
KDCVIVTCVRANTMQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENQHWNHLIQDA
QKRGAIIKTCDKNYRHDAAKILKLKPVLQRSLTHPPAVAPEASRPQGGLPSNKLDSEFAK
TSFTSSLYHTPPDSKESSGTVTTKDPERPLVQDRLRDPRLLRRMGLDPEAKGMCLRDPQP
LSPQHPGATPPSGEPGFPASHQDLGSAQQSTARGTALNNHKPHAQWEPPAAGTDVSTSKR
RCDWEEGLSHRRETRAFSEGDQDRWSPESHYSKRSPGWDKRGLQKEDCSSKKRRLL
NT seq
8091 nt
NT seq
+upstream
nt +downstream
nt
atgcttcagaggaggtgcagaatgagcacatgttgttggtgtacgccaggtggcatttcc
accgttgacttcctacagcgctatgcatccgagacccactccagtgagtttcaaacagct
gatgaagacctctgctactgcttagagtgtgtggccgaataccacaaagcaagggatgat
ttaccattcttgcatgaggttttatgggaattagaaaccttacgtctcataaattacttt
gaaaaatccatgaaggcagaaattggagatgatgatgagttgtatatagtagacaacaat
ggagaggcacaactgtttgactttaccggccaagactttgaaaataagcttcgagttcct
cttcttgaaatactgaaatatccttacctgcttttacatgagcgtgttaatgaattatgt
gttgaagcactttgtcggatggaacaagctaattgctcctttcaggtttttgacaaacat
ccaggcatctatttgtttctggtccatcccaatgaaatggttcggcgttgggctatcctg
accgcaagaaatttgggaaaagtggacagagatgattattatgacttgcaggaggttttg
acttgcctttttaaagtcattgaattggggcttttggaaagtccagacatttatacttct
tctgttctcgagaagggtaaactgattcttctgccctcacacatgtacgataccaccaac
tacaaaaactattggttaggtatttgcatgttgctgaccattctggaggagcaggccatg
gactcactattgctgggctcagacaaacagaatgattttatgcaatcaatacttcacacc
atggagaggcaagcagatgatgatagtgtggatcctttttggccagcattacactgtttc
atggtgattctggatcgccttggatctaaggtctggggtcagcgtattgatcctattgag
gcatttcaaaccattatcaacaatgtgagctacaataaagagatccaaaatatacggaac
agctctgtaaggaccaagttagaaccggaatcatattcggatgatgccacttgcagccag
attgtatacaattataatcccgaaaagaccaaaaaggattcagggtggagatcagccatt
tgcccagattattgtcctaacatgtatgaagagatggaaacattagccagtgtgcttcag
tcagatattggtcaagacatgcgtgttcataacagcacctttctgtggttcatccctttt
gttcagtccctcatggatcttaaggatttgggtgtggcttatatagtagaggttattcat
catctgcactccgaagtcaaggatgtcctcaaccaaacagatgccatgtgtgacaaagtt
actgaattttttcttctgattttggtgtccgtgattgagctgcatagaaataaaaaatgt
ctgcatttgctgtgggttagttcccagcaatgggtagaagccgttgtaaaatgtgccaag
ctacctaccactgcatttgcacggagttctgagaagtcatctggaaattgctccaaagga
acagcaatgatatcatctctgtcattgcattcaatgccatcgaattctgtacagctggct
tgtgtgcagctgattagaagtctccttaaagaaggttatcagcttgggcagcaaacttta
tgtaagcgattctgggataaactcaatttatttctgcgtggaaatttatctctaggttgg
cagttgactactcaggaaacccatgagttacaaacttgtttaaagcaaattattaaaaac
ataaaagtcaaagtacctcagtgtaacacttttgtggatttgagtcctgcaggtaaaagc
tctccggcatcttacagtaaagaagaaagtgaacaaatagagaggaggtccaataaagat
ctgcactgtctggaaaactccagcccaacattttctaaagaaccaatgaaagctgaggca
tatcaaatacaagagaatatattgattaaagcaagtaacactatagaagaggataatgag
caaaattatataaaagattggaaactagaagatcatctctcagccgagtcatgcataaag
aagagtagtaaaaacgttttcactgaaagagctcaagatcaagttaaaataagtacaggg
aagcagaagtccgtgaaagagaattgtacttcaagaaatgtactgcagaattgtacttca
aggaatggtccagaaaggggatgtgacagaggaataataatgtcaacacgtttgttgacc
gactctagcactgattctctggagaaggcgtgcacatcaaatgaggatttatctttcaag
gatgatgctcttggcaaaacctcaaaatcaaaaactaaggcacataaagatgaaatctgt
gctaagttatcacatgtaataaagaagcaacacaggaaaagtactttgatcaataatact
ggtaatttagaggaaaacctaactgtgtctaacattgacagtttctattcaaggaaagat
tcgggaggtcagaaaggggatggcttcatgcacaatctctctttagaccctctcggcatt
ctggatgaaaaaaatggggaacaaaaatctcaaaacagtttattgctgaaaaagaaacaa
ctgaagagtgaagagttagatattttctcttcccatgaaaacagctatcaaatacaggaa
tgtcacattgatgataaagatttggtctcatttacggaagtgaccaacactttcgtgagg
aaaacgtctcccttcaaagatcctgtgactgttcttgaatcaaaagataaggaaattagc
aagaataccagtcagatgtcttctcacttgagagaacaagctcctggcctcagtcctcag
tctgacaccttaacagattctcagatagacagagacctccacaagttatctttaatagct
caagccagcgttattaagttcccatcagattcaactcaaaaaagttcatcccagctacaa
agaagagtgaaagacgacagaagatgtttcccggctgaccagaataatactggggaagcc
tgtcggggccagattattattatttcagattctgatgatgatgatgaaggaattctaggt
tttgagaaacatattaaacaagataaaataggcatcaagaaagaatgcccggagcagcat
acttcaatagctagtacgaatgtggaaaagaagttaataaaggaagaggagacaaagtcc
cttttgcagtttgaggaatcagattctcagttttttgagtttgaaagtccatgtgaagtg
ttttcagtttggcaagatcaggaaccagacaagaattcagttcaagagagtgaaaaaaac
tcttgttcgactgacatagctgatatcacgaatgattggggttatgagacagattatgta
tctgaagaggttattaagaaggtagcagagggcattgaaaaacacacagagccacagagt
agtatttctgttggggaattttgtgaaattgaagtaaaaaaacgtaagagaaaacgattt
gaaaaacctatggctgaaggtcctctaaggccttcaccttctggtagaaatgagaaccag
cctgatattcttaatgagagaggtctgactgaaaatgattttaaaagtatggacctaagg
acagtgagtcccagttcaagtgttcagagagacaaagacactacggtttcactaaagaag
tcttctccaaagcttcatacttactccaaacccattagaagagtcccactttctaaaact
cctaagaaaacacattcagataccaagaaagggcagaacaaaagttcaaattatataagt
tgtaggacaactcctgctatagttccaccaaagaaatttcgccagtgccctgaaccaact
ttaacggttgagaaacttggtctgaagaaggctcctcgtagggcatttgagttgtctcag
cgatctctagagagtttagttaagttacgccaccatggcaaaactgttggagtggttgat
actagcaaaaagactaagttaatttctcctcagactctctctgtcagaaacaataagaaa
ctgctgacaagtcaagatcttcagttgcgaaggcagatgagacccaaatcacaacaaaat
agacaaggacttttggattatgaaaataaagatactacaagagcagggctgtgtacagca
caaaattctgacatacctgtcccagaatcagatggttcagattatagttacaaaggagga
actgaggtggttgctaacaacactgggaaacaaataaaacgtgtgtcttcggaaccagaa
cccgtgaaaacaaaatatgtgtctcaggtgaccaatgatgcttgtcttttgaaccagtct
gctgctgttgtgttgaatggaagaataccaacaaatgaaatcattgtctctgcttcagca
gaccccttaggcggtggtgaccgaacagtacatcatttagagttggcaactttgaaagac
ggagagcctgaatccaacagtgatacagaagatgagaatatatttctaacacagcacgat
cctgaagatatggatttgtgttcacagatggagaatggtaatgagaaactcattgaagta
gttcatggcaaagatacagctcaggtggaagaagattctgtaagtcagcctcagttggaa
tcttggagtagcacaaaatgtaagtacaaagattgtgttgaaaccccgaaaaaccagggt
gactactgctcaaaacactgtgaagctaaagcagcagatgaagatgtatttcgtaaacct
ggcttgcccctttctgcatctaagccttccagaccttccactgcgaagatttttagctca
agtagtacttcacgaattgctaatctttccaagtctttggaaagtacctctgcacttcca
ccagctctaaaaaataagtcaaatggggcacaggctgttttgaaagtcccacagccagcc
tctctggtgtctccaaagccagtgggtgaagtgaagagtttgggcaatgtttttcatccc
cagactccaagtaattgcagcaggcaaggttacaaactgacatttggtgaaagcaaatcc
ttctcggcttcctctccggtccacattctcttgtcatcacagtccatctctgacactttt
gtcaaagaggtcttaaaatggaaatacgaaatgtttgtgaactttgatcagtgcgggccc
ccagcaagcctttgtcagtccatctcaagacctgtgcctgtcagatttcaagattgtgga
gattattttaatgtttttttccctttgatgatattgaatacttttgaaacagtggcacag
gagtggatcagctctccaaacaaagagaaattctatcagttgcatttacgaaaatttcct
gctgattataaaaaatactgggagtttgtggttcatcttgaggaatgtgaactagctaaa
caggttcatccaaaggaaaatgatttggtgtttttggttcctgaaagacaaaatggagag
aagaaagatacagagagaaatcgcatgcaagatctccgtgaatatcattgtggttatatt
cataagtttcgccgcacttcagtcatgcgcagtgggaaatctgagtgttccctttccatc
cagactcaagataatttgccagtcaatttaaatgaactcgtgaaatgcgttgtaatcagt
tctctggtaactacacaaaggaagttgaaagccatgtctttgttgagtggacggaaccaa
ctggccagagctgttctgaatccaaaccccatggacttctgtacaaaagatttactaact
acaacatctgagagaattatcgcctacttaagagatttcaacgaagaccaaaagaaagcg
atagaaactgcatatgccatggtcaaacactccccgtcagttgccaagatctgtctgatt
catggaccacctggaacaggaaaatcaaaaactattgttggcctcctgtaccgcctcctg
acagagaaccagaggaaggggcattcagatgaaaactccaatgccaaaatcaaacaaaac
cgtgtccttgtgtgtgcgccttccaacgcagctgttgatgaacttatgaaaaaaatcatc
ctcgaatttaaagaaaaatgtaaagacaagaagaatcctttgggaaactgtggagatata
aatttagtacgtctcggtccagaaaagtctattaataatgaggtcctaaaattcagtttg
gacagccaagttaaccacagaatgaaaaaagacttaccttctcatgttcaggagatgcat
agaagaaaggaatttctagatcatcaacttgatgaactttcccgccagcgtgctttatgc
cgaggtggaagggaaatacagaggcaagaattagatgaaaaaattgcgaaagtttcaaaa
gagaggcaggaactagcttctaaaattaaggaggttcaaggacgcccacaaaaaacacag
agcatcatcatcttagagtctcatgtcatctgctgcacattgagcacgagtggtggttta
ctgcttgagtctgcttttcgtgggcaagggggtgtccccttcagttgtgtcattgtcgat
gaggccgggcagtcttgtgaggttgagactcttactccactcatccatcgttgtaacaag
ctcatcctcgtaggagatcctaaacagctccctcccacggtcatttctatgaaagcacag
gaatatggctatgaccagtcaatgatggcgcgcttctacaagctgctggaagacaacgtg
gagcacaatatgatcggcaggctgcctattttacagcttactgttcagtacaggatgcac
ccagacatatgtctctttccctctaactatgtttataacagaagcttgaaaacaaataga
cagactgaaaccaatcggtgttcatcagactggccatttcaaccttacctggtgtttgat
gtcggagacggttcagaaagacgggataatgactcatatgtaaatgttcaagaaataaaa
ctggtaatggaaataattaaacttattaaagacaaaagaagggatgttactttccggaac
attggcataataacccattacaaggctcagaagacgatgattcagaaggatttggacaaa
gaatttgataaaaaagggccagcggaagtagataccgtggatgggttccagggccggcag
aaggattgcgttattgttacgtgcgtcagagcaaataccatgcagggctcaattggattt
ctggcaagtttgcagagactgaacgtcaccatcacacgagccaagtacagcctcttcatc
ctcggacatttaaggaccctcatggaaaatcagcactggaaccacctgattcaggatgca
cagaagcggggcgccatcatcaagacgtgcgacaagaactacaggcacgacgcagcgaag
attctgaagctcaagcccgtgctgcagagaagtctgactcacccgccagccgtagccccg
gaggcgtccagaccccagggcggcttgcccagcaacaagcttgacagtgaatttgccaag
acatctttcacttcttccctgtatcacacgccccctgactccaaggaatcttctggtact
gtcactacaaaggaccctgaaaggcctctcgttcaggaccggcttcgggacccacgactg
ctcaggaggatgggcctggaccccgaagccaaagggatgtgcctaagggatccgcagccc
ttgagcccccagcaccccggagcgacacctccctcgggcgagccaggcttccctgccagt
caccaggatctgggtagcgcacagcagtccactgccagaggaaccgctctgaacaaccac
aaacctcacgcgcagtgggaacctccagctgctgggactgatgtctccacaagtaaaaga
agatgtgactgggaagaaggactcagccacagaagagagacccgggctttcagtgagggc
gaccaggacaggtggagcccggagagccactactcgaagaggagccccggctgggacaag
aggggactgcagaaggaggactgcagctcaaagaaaagaaggcttttatag
DBGET
integrated database retrieval system
