Odobenus rosmarus divergens (Pacific walrus): 101371113
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Entry
101371113 CDS
T05148
Symbol
ERN1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
oro
Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro04140
Autophagy - animal
oro04141
Protein processing in endoplasmic reticulum
oro04210
Apoptosis
oro04932
Non-alcoholic fatty liver disease
oro05010
Alzheimer disease
oro05012
Parkinson disease
oro05014
Amyotrophic lateral sclerosis
oro05016
Huntington disease
oro05017
Spinocerebellar ataxia
oro05022
Pathways of neurodegeneration - multiple diseases
oro05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
oro00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
101371113 (ERN1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
101371113 (ERN1)
09143 Cell growth and death
04210 Apoptosis
101371113 (ERN1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
101371113 (ERN1)
05012 Parkinson disease
101371113 (ERN1)
05014 Amyotrophic lateral sclerosis
101371113 (ERN1)
05016 Huntington disease
101371113 (ERN1)
05017 Spinocerebellar ataxia
101371113 (ERN1)
05022 Pathways of neurodegeneration - multiple diseases
101371113 (ERN1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101371113 (ERN1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
101371113 (ERN1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oro01001
]
101371113 (ERN1)
Enzymes [BR:
oro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
101371113 (ERN1)
Protein kinases [BR:
oro01001
]
Serine/threonine kinases: Other
IRE family
101371113 (ERN1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
PQQ_2
PQQ
Pkinase_fungal
Kdo
PQQ_3
Motif
Other DBs
NCBI-GeneID:
101371113
NCBI-ProteinID:
XP_004405918
UniProt:
A0A2U3WBU0
LinkDB
All DBs
Position
Unknown
AA seq
975 aa
AA seq
DB search
MPARLLLALLALLLLPGPGIFGSPSTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKED
PVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYMG
KKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNATY
FDYAASLPEDDGDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLKK
VMHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPSM
VHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKNRLNYLRNYW
LLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKKSFEEVINLVDQTSENAPTTVS
QDVEEKYEHAPAKPEAPVDSMLKDIATIILSTFLLIGWVAFIITYPLSMHQQQQLQHQQF
QKELEKIQLLQQQLPFHPPGDIAQDAELLDSSGLYSESSGTSSPSTSPRASNHSLHSTGS
ASKAGTSPFLDQDDEDEETSMVIVGKISFCPKDVLGHGAEGTIVYRGMFDNRDVAVKRIL
PECFSFADREVQLLRESDEHPNVIRYFCTERDRQFQYIAIELCVATLQEYVEQKDFAHLG
LEPITLLQQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRTKAMISDFGLCKKLAVGR
HSFSRRSGVPGTEGWIAPEMLSEDCKDNPTYTVDIFSAGCVFYYVISEGSHPFGKSLQRQ
ANILLGAYSLDCLHPEKHEDVIARELIEKMIAMDPQKRPSAKHVLKHPFFWSLEKQLQFF
QDVSDRIEKESLDGPIVKQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDLLR
AMRNKKHHYRELPVEVRETLGSLPDDFVRYFTSRFPYLLSHTYRAMEPCGHERLFQPYYF
HEPPEPRPPVTPDTL
NT seq
2928 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggctactgctggcgctgctggcgctgctgctgctgcctggccccgggatt
tttggaagtcccagcacagtgacacttcctgaaaccttgttgtttgtgtcaactctggat
ggaagtttgcatgctgttagcaagaggacaggctcgatcaaatggactttaaaagaagat
ccggttctgcaggttccaacacatgtggaagagcctgccttcctcccagatcccaatgat
ggcagcctgtatacgcttgggggcaagaataatgaaggcctgacgaaacttccttttacc
atccccgagttggtacaggcatccccatgccgaagttcagacggaattctctacatgggt
aaaaagcaggacatttggtacgttatcgaccttctgactggggagaagcagcagaccctg
tcatcggcctttgcagacagcctctgcccgtctacctctctgctgtatctcgggcgaacg
gagtacaccatcaccatgtacgacaccaaaacccgtgagctccggtggaacgccacctac
tttgactatgcagcctctctgcccgaggacgacggggactacaagatgtcccactttgtg
tccaacggcgacgggctggtggtgaccgtggacagtgaatccggcgacgtcctgtggatc
caaaactacgcttcccccgtggtggccttttatgtctggcagagggagggtctgaagaag
gtgatgcacatcaacgtcgccgtggagaccctgcgctacctgaccttcatgtctggggag
gtgggccgcatcaccaagtggaagtacccgttccccaaggagacagaggccaagagcaag
ctgacgcccaccctgtatgttgggaaatactctaccagcctgtatgcctccccctccatg
gttcacgagggggtcgccgttgtgccccgaggcagcactcttcctttgctggaaggcccc
cagaccgacggggtcaccattggggacaaaggggagtgtgtgatcacgcccagcacagac
ctcaagtttgaccctgggctcaaagggaagaacaggctcaactacctgaggaactactgg
cttctgattggacaccatgaaacccccctgtctgcgtctaccaagatgctggagagattc
cccaacaacctgcccaaacatcgggaaaacgtgattcctgccgattcagagaagaagagc
tttgaggaagttatcaacctggttgaccagacgtcagaaaacgcgcctaccaccgtttca
caggatgtggaagagaaatacgagcatgcccctgccaagcccgaggcccccgtggactcc
atgctcaaggacattgccaccatcatcctgagcaccttcctgctcatcggctgggtggcc
ttcatcatcacataccctttgagcatgcatcagcagcagcagctccagcaccagcagttc
cagaaggaactagagaaaatccagctcctgcaacagcagctgcccttccatccacctgga
gacatagctcaggatgctgagctcttggactcatccggcctatactccgagagctcgggc
accagcagccccagcacgtcccccagagcctccaaccactcgctgcactccactggctcg
gcctccaaggctggcaccagccccttcctggatcaggacgatgaggatgaggaaaccagc
atggtgatagttgggaagatttcattctgtcccaaggatgtgctgggtcacggagctgag
ggtacgattgtgtaccggggcatgtttgacaaccgcgacgtggctgtcaagaggatcctc
cctgagtgtttcagtttcgcggaccgcgaagtccagctacttcgagaatcggatgagcac
cccaacgtgatccgttacttctgcacagagagggaccggcagttccagtacattgccatc
gagttgtgtgtggccaccctgcaggagtacgtggagcagaaggactttgcccacctcggc
ctggagcccatcaccttgctgcagcagaccacctcgggcctggcccatctgcactccctc
aacattgttcatagagacctgaagccccacaacattctcctctccatgcccaacgcgcat
ggcaggaccaaggccatgatctcggacttcggcctctgcaagaagctggcagtaggccgg
cacagtttcagccgccgctcaggagtgccgggcacggaaggctggatcgctccggagatg
ttgagcgaagactgcaaagacaacccgacctacacagtggacatcttctctgcaggctgt
gtcttttactatgtgatctcagaaggcagccacccttttggcaagtccctgcagcggcag
gccaacatcctcctgggtgcctacagcctcgactgcttgcaccccgagaagcacgaagat
gtcattgcccgggaattaatagagaagatgatcgcaatggatcctcagaaacgcccgtcc
gcaaagcacgtgctgaaacatccgttcttctggagcctggaaaagcagctccagttcttt
caggacgtgagtgaccgaatagaaaaggagtccctggacggcccgatagtgaagcagctg
gagcgaggcgggagagctgtggtgaagatggactggagggagaacatcaccgtccccctg
caaacagatctgcggaaattcagaacctataaaggtggctccgttcgagacctcctccga
gccatgagaaacaagaagcaccactaccgggagctccccgtggaggtgcgggagacgctg
ggttccctccctgacgacttcgtgcgctacttcacgtcccgcttcccctacctcctctcc
cacacctaccgggccatggagccgtgcggccatgagcggctcttccagccctactatttc
cacgagcccccagagccccggcctccagtgactccagacaccctttga
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