Odobenus rosmarus divergens (Pacific walrus): 101384632
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Entry
101384632 CDS
T05148
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
oro
Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro00230
Purine metabolism
oro00670
One carbon pool by folate
oro01100
Metabolic pathways
oro01523
Antifolate resistance
Module
oro_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
oro00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
101384632 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
101384632 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
101384632 (GART)
Enzymes [BR:
oro01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
101384632 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
101384632 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
101384632 (GART)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_N
GARS_C
AIRS
ATP-grasp
ATP-grasp_2
CPSase_L_D2
ATP-grasp_4
ATP-grasp_3
Dala_Dala_lig_C
RimK
ATP-grasp_5
Motif
Other DBs
NCBI-GeneID:
101384632
NCBI-ProteinID:
XP_004406332
UniProt:
A0A2U3WCV7
LinkDB
All DBs
Position
Unknown
AA seq
1010 aa
AA seq
DB search
MAAQVLVIGSGGREHTLAWKLAQSNHVKHVLVAPGNAGTACLEKISNTAISINDHTALAQ
FCKDEKIEFIVVGPEAPLAAGIVGNLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRHGIP
TARWRAFTKPEEACSFIMSADFPALVVKASGLAAGKGVIVAKSTEEACRAVQEIMQDRAY
GAAGETIVIEELLEGEEVSCLCFTDGRTVAPMPPAQDHKRLLEGDHGPNTGGMGAYCPAP
QVSKDLFLKIKNIILQRTVDGMQQEGMPYTGVLYAGIMLTKDGPKVLEFNCRFGDPECQV
ILPLLKSDLYEVIQSTLDGLLCTSLPVWHENRTAITVVMASKGYPGDYTKGVEITGFPEA
QALGLEVFHAGTALKDGKVVTNGGRVLTVTAIQENLILALEEAKKGLAAIKFEGAIYRKD
IGYRAVAFLQQPRGLTYKESGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLFDLK
AAGFKDPLLASGTDGVGTKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSC
GKLDLNTTEAVVAGIARACGKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQKLP
HLERITEGDVVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPEGCGDQTLGDLLLTPTR
IYSHSLLPVLRAGHIKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRVPRIFSWLQQEG
HLSEEEMARTFNCGIGAALVVSKDLTEQILRDIKQHKEEAWVIGKVVAWPEGSPRVKVKN
LIETMQINGSVLENGTLKNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSCAHIVVV
ISNKAAVAGLDKAERAGIPTRVINHKLYKSRVEFDTTIDQVLEEYSTDIVCLAGFMRILS
GPFVRKWDGKMLNIHPSLLPSFKGSNAHEQALEAGVTVTGCTVHFVAEDVDAGQIILQES
VPVKRGDTVATLSERVKLAEHKIFPAALQLVASGAVQLGENGKIRWVTEE
NT seq
3033 nt
NT seq
+upstream
nt +downstream
nt
atggcagcccaagtacttgtaattggcagtggaggaagggaacacacactggcctggaaa
cttgcacagtctaatcatgtcaaacatgtgttggttgccccaggaaatgcaggcactgcc
tgcttggaaaagatttcaaatactgccatctcaatcaatgaccacactgcccttgctcag
ttctgcaaagatgagaaaattgaattcatagttgttggaccagaggcacctctggctgct
ggaattgttgggaacctgacatctgcaggagtccgatgttttggtcccactgcagaagca
gctcagttagagtccagcaagagatttgccaaagagtttatggaccgacatggaatccca
actgcacggtggagagctttcaccaaacctgaagaagcctgcagctttataatgagtgca
gacttccctgctttggttgtgaaggccagtggtcttgcggctggaaaaggggtgattgtt
gccaagagcacagaagaggcctgcagggctgtacaggagatcatgcaggatagagcttat
ggagcagctggagaaacaattgtcattgaagaacttcttgaaggagaagaggtgtcttgt
ctgtgcttcactgatggaaggaccgtggcccccatgcccccagcacaagaccataagcga
ttgctggagggagatcatggccccaacacagggggaatgggagcctactgtccagcacct
caggtttctaaggatttgttcctgaaaataaaaaatatcattcttcagaggacagtggat
ggcatgcagcaggagggtatgccatacacaggtgttctctatgctggtataatgctgacc
aaggatggcccaaaagttctggagtttaattgccgtttcggtgatccagagtgccaagtg
atcctcccacttcttaaaagtgatctttatgaagtgatccagtctaccttggacggcctg
ctgtgcacatctctgcctgtttggcatgaaaaccgcactgccataactgtcgtgatggca
agtaaaggctatccaggagactacaccaagggtgtggagataacagggtttcctgaagct
caagctttaggactggaggtgttccacgcaggcactgccctgaaagatggcaaagtggtg
actaacgggggtagagtccttacggtaacagcaattcaggaaaatctcatcttggccctt
gaagaagccaagaaaggactagctgctataaaatttgagggagccatttacaggaaggac
attggctatcgtgccgtagcttttctccagcagcccaggggcctgacttacaaggaatct
ggggtagacattgcagctggaaatatgctggttaagaaaattaaacctttagcaaaagct
acctccagaccaggctgtgatgttgatcttggaggttttgctggtctttttgatttgaaa
gcagctggtttcaaagatcctcttctggcaagtggaacagatggtgttggtactaaactg
aagattgcccaacagtgtaataaacatgataccattggtcaagatttggttgcaatgtgt
gtcaatgacattctggcccaaggggcagagcctcttttcttcctcgattacttttcctgt
ggaaaacttgacctcaatacaactgaagctgttgttgctggaatcgccagagcttgtgga
aaagctggatgtgctctccttggaggtgaaactgcagaaatgcctgacatgtatcctccg
ggagaatatgacctagctggttttgccgttggtgccatggagcgggatcagaaactccct
cacctggaaagaatcactgaaggggatgttgttattggaatagcttcatctggtcttcac
agcaatggattcagccttgtaaggaaaattgtagcaaaatcttccctccagtactcgtct
ccagcacctgaaggctgtggtgaccagaccttaggggacttacttctcactccaaccaga
atctacagccattcactgctacccgtcctacgtgcaggacacatcaaggcctttgcccac
attactggtgggggattgctagaaaacatccccagagtccttcctcagaagtttggggtg
gatttagatgcccagacctggagggtccccagaatcttctcatggttacagcaggaagga
cacctctctgaggaagagatggccagaacatttaactgtgggattggggctgccctcgtg
gtatcaaaggatctgacagagcagattctgagggatattaagcagcacaaggaagaagcg
tgggtgattggcaaggtggttgcatggcctgaaggttctcctcgtgtgaaagtgaagaat
ctgatagaaaccatgcaaataaatgggtcagtattggagaatggcaccctgaaaaatcat
ttctctgtccagccaaaaaaggcaagagtggctgttttaatatctggaacaggatcaaac
ctgcaagctctcatagacagtacaagggaaccaagtagctgtgcacacattgttgttgtt
atctctaacaaagccgcagtggctggtttagataaagccgaaagagccggaattcccacc
agagtaattaatcataaattatataaaagtcgtgtagaatttgacaccacaattgaccaa
gtccttgaagagtactccacagacatagtctgtcttgcaggattcatgagaattttatct
ggcccctttgtcaggaaatgggatgggaagatgctcaacatccacccatccttgctgcct
tcttttaagggttcaaatgcccacgagcaagccctagaagccggggtcacagtcactggg
tgtactgtgcactttgtagctgaagatgtagatgctggacaaattattttacaagaatct
gttccagtgaagagaggtgacactgttgcaactctgtctgaaagagtgaaattagcagag
cacaaaatatttcctgcagccctccagctggtggccagtggagctgtacagcttggagaa
aacggcaagattcgttgggtcacagaagagtga
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