Odobenus rosmarus divergens (Pacific walrus): 101386211
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Entry
101386211 CDS
T05148
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
oro
Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521
EGFR tyrosine kinase inhibitor resistance
oro01522
Endocrine resistance
oro04010
MAPK signaling pathway
oro04014
Ras signaling pathway
oro04015
Rap1 signaling pathway
oro04066
HIF-1 signaling pathway
oro04068
FoxO signaling pathway
oro04081
Hormone signaling
oro04114
Oocyte meiosis
oro04140
Autophagy - animal
oro04144
Endocytosis
oro04150
mTOR signaling pathway
oro04151
PI3K-Akt signaling pathway
oro04152
AMPK signaling pathway
oro04211
Longevity regulating pathway
oro04213
Longevity regulating pathway - multiple species
oro04510
Focal adhesion
oro04520
Adherens junction
oro04550
Signaling pathways regulating pluripotency of stem cells
oro04730
Long-term depression
oro04913
Ovarian steroidogenesis
oro04914
Progesterone-mediated oocyte maturation
oro05200
Pathways in cancer
oro05202
Transcriptional misregulation in cancer
oro05205
Proteoglycans in cancer
oro05214
Glioma
oro05215
Prostate cancer
oro05218
Melanoma
oro05224
Breast cancer
oro05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
oro00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101386211 (IGF1R)
04014 Ras signaling pathway
101386211 (IGF1R)
04015 Rap1 signaling pathway
101386211 (IGF1R)
04066 HIF-1 signaling pathway
101386211 (IGF1R)
04068 FoxO signaling pathway
101386211 (IGF1R)
04151 PI3K-Akt signaling pathway
101386211 (IGF1R)
04152 AMPK signaling pathway
101386211 (IGF1R)
04150 mTOR signaling pathway
101386211 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
101386211 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
101386211 (IGF1R)
04140 Autophagy - animal
101386211 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
101386211 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101386211 (IGF1R)
04520 Adherens junction
101386211 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
101386211 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
101386211 (IGF1R)
04914 Progesterone-mediated oocyte maturation
101386211 (IGF1R)
09156 Nervous system
04730 Long-term depression
101386211 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
101386211 (IGF1R)
04213 Longevity regulating pathway - multiple species
101386211 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101386211 (IGF1R)
05202 Transcriptional misregulation in cancer
101386211 (IGF1R)
05205 Proteoglycans in cancer
101386211 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
101386211 (IGF1R)
05214 Glioma
101386211 (IGF1R)
05218 Melanoma
101386211 (IGF1R)
05215 Prostate cancer
101386211 (IGF1R)
05224 Breast cancer
101386211 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
101386211 (IGF1R)
01522 Endocrine resistance
101386211 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
oro01001
]
101386211 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
oro04090
]
101386211 (IGF1R)
Enzymes [BR:
oro01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
101386211 (IGF1R)
Protein kinases [BR:
oro01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
101386211 (IGF1R)
CD molecules [BR:
oro04090
]
Proteins
101386211 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Motif
Other DBs
NCBI-GeneID:
101386211
NCBI-ProteinID:
XP_012419631
LinkDB
All DBs
Position
Unknown
AA seq
1304 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVTQVTNTTMSSRSRNTTVADTYNITDPEELETEYPFFES
RVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTW
ESRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGN
YTARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHR
KRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKG
VVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIME
LMTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARN
CMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGV
VLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFL
EIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPGMGRAGI
NT seq
3915 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccgggcatcgacatccgc
aacgactatcagcagctgaagcgtctggagaactgcacggtgatcgagggctacctccat
atcctgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctggagagcctcggggacctcttc
ccgaacctcacagtcatccgcggctggaagctcttctacaactacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaatctgaggaacattactcggggggcc
atcaggattgagaagaatgccgacctctgttacctctccacggtggactggtccctgatc
ctggatgccgtgtccaataactacatcgtgggcaacaaacccccaaaggaatgcggggac
ctgtgtccggggacaatggaggagaagcccttgtgtgagaagacaaccatcaacaacgag
tacaactatcgttgctggactacaaaccgttgccagaaaatgtgcccgagcgcgtgcggg
aagcgggcgtgcaccgagaacaacgagtgctgtcaccccgagtgtctgggcagctgcagt
gcgcccgacaacgacacggcctgcgtggcgtgcaggcattactactatgccggcgtctgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgttgcgtggaccgcgac
ttctgcgccaacatacccagcgccgagagcagcgactccgaggggtttgtgatccacgac
ggcgagtgcatgcaggagtgcccctcggggttcatccggaacggcagtcagagcatgtac
tgcatcccttgtgaaggtccttgccccaaggtctgtgaggaagaaaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaatatccgccgaggcaataacattgcctcagaactggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagatccgccattcccatgccttggtctccttgtcc
ttcctaaaaaaccttcgccagatcttaggagaggagcagctagaagggaactactccttc
tatgtcctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagctgggaaaatgtactttgctttcaatcccaaattgtgcgtctccgagatttac
cgcatggaggaagtgacagggactaaggggcgccagagcaaaggggacataaacaccagg
aacaacggagagcgagcctcctgtgaaagtgacgtcctgcatttcacctctacaaccacg
tggaagaatcgcatcatcataacgtggcaccgttaccggccccctgactacagggacctc
atcagcttcactgtctactacaaggaagcaccttttaaaaatgtcacggagtatgatgga
caggatgcctgcggctccaacagctggaacatggtggatgtggacctccctcccaacaaa
gacgtcgagcctggcattctgctgcacggactgaagccctggacgcagtatgctgtgtat
gtcaaggcggtgaccctcaccatggtggagaacgaccacatccgtggggccaaaagtgaa
atcttgtacattcgcaccaatgcttcagtcccttccattcccctggacgttctttccgcg
tccaactcctcttctcagctcattgtgaagtggaacccgccctccctgcccaacggcaac
ctcagttactacatcgtgagatggcagcggcagcctcaggacagctacctttaccggcac
aactactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacgtg
gaagaggtgacggagaatcccaagaccgaggtgtgtggcggagagaaggggccttgttgc
gcctgccccaaaaccgaggccgagaagcaggccgagaaggaggaggccgagtaccgaaaa
gtcttcgagaactttctgcacaactccatctttgtgcccagacctgaaaggaagcggaga
gacgtcacacaagtcactaacaccaccatgtctagccgaagcaggaacaccacggtggca
gatacctataatatcacagacccagaagagctcgagacagaataccctttctttgagagc
agagtggataacaaggagagaactgtaatctctaacctccggccttttactttgtaccgc
attgacatccacagctgtaaccacgaggctgagaagctgggctgcagcgcctccaacttt
gtttttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgg
gagtcgaggcctgaaaactccatctttctaaagtggccggaacctgagaatcccaacgga
ttgattctaatgtatgaaataaaatatggatcacagatcgaggatcagcgggaatgtgta
tcgagacaggagtacaggaagtatggaggcgccaagcttaaccggctcaaccccgggaac
tatacggcccggatccaggccacctctctctctgggaatgggtcctggacggatcctgtg
ttcttctacgtcccagccaaaataacgtatgaaaacttcatccatctgatcatcgctctg
cctgttgctgtcctgttgatagtgggagggctggttataatgttgtatgtcttccacagg
aaaagaaataacagcaggctggggaatggagtgctgtacgcttccgtgaacccagagtac
ttcagcgccgccgacgtgtacgtacctgacgagtgggaagttgctcgagagaagatcacc
atgagccgagagctggggcagggctcatttgggatggtatacgaaggagttgccaaaggc
gtggttaaagatgagcccgaaaccagggtggccattaaaacagtgaacgaggccgcgagc
atgcgtgaaaggattgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcac
catgtggtgcggttgctgggcgtagtgtcccagggccagccgacgctggtcatcatggaa
ctgatgacacggggggatctcaaaagctatctcaggtctctgaggccagaaatagagaat
aatccagtcctagcacctccaagcctaagcaagatgatccagatggctggggagattgca
gatggcatggcatacctcaacgccaacaagtttgtccacagagaccttgctgcccggaac
tgcatggtggccgaagatttcacagtcaaaatcggagattttggtatgacgagagacatc
tacgagacagactattaccggaaaggaggaaaggggttgctgcctgtgcgctggatgtcc
cccgagtctctcaaggatggagtcttcactactcactccgacgtctggtccttcggcgtc
gtgctctgggagatcgccacgctggccgagcagccctaccagggcttgtccaacgagcag
gtccttcgcttcgttatggagggcggccttctggacaagccggacaactgccctgacatg
ctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctg
gagatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctac
tacagcgaggagaacaagccgcccgagcccgaggagctggacctggagccaggcatgggg
cgagctggtatctag
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integrated database retrieval system
