KEGG   Odobenus rosmarus divergens (Pacific walrus): 101386334
Entry
101386334         CDS       T05148                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X1
  KO
K05459  insulin-like growth factor 1
Organism
oro  Odobenus rosmarus divergens (Pacific walrus)
Pathway
oro01521  EGFR tyrosine kinase inhibitor resistance
oro01522  Endocrine resistance
oro04010  MAPK signaling pathway
oro04014  Ras signaling pathway
oro04015  Rap1 signaling pathway
oro04066  HIF-1 signaling pathway
oro04068  FoxO signaling pathway
oro04081  Hormone signaling
oro04114  Oocyte meiosis
oro04115  p53 signaling pathway
oro04150  mTOR signaling pathway
oro04151  PI3K-Akt signaling pathway
oro04152  AMPK signaling pathway
oro04211  Longevity regulating pathway
oro04213  Longevity regulating pathway - multiple species
oro04510  Focal adhesion
oro04550  Signaling pathways regulating pluripotency of stem cells
oro04730  Long-term depression
oro04750  Inflammatory mediator regulation of TRP channels
oro04913  Ovarian steroidogenesis
oro04914  Progesterone-mediated oocyte maturation
oro04935  Growth hormone synthesis, secretion and action
oro04960  Aldosterone-regulated sodium reabsorption
oro05200  Pathways in cancer
oro05202  Transcriptional misregulation in cancer
oro05205  Proteoglycans in cancer
oro05214  Glioma
oro05215  Prostate cancer
oro05218  Melanoma
oro05224  Breast cancer
oro05410  Hypertrophic cardiomyopathy
oro05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:oro00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101386334 (IGF1)
   04014 Ras signaling pathway
    101386334 (IGF1)
   04015 Rap1 signaling pathway
    101386334 (IGF1)
   04066 HIF-1 signaling pathway
    101386334 (IGF1)
   04068 FoxO signaling pathway
    101386334 (IGF1)
   04151 PI3K-Akt signaling pathway
    101386334 (IGF1)
   04152 AMPK signaling pathway
    101386334 (IGF1)
   04150 mTOR signaling pathway
    101386334 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    101386334 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    101386334 (IGF1)
   04115 p53 signaling pathway
    101386334 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101386334 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    101386334 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    101386334 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    101386334 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    101386334 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    101386334 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    101386334 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    101386334 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    101386334 (IGF1)
   04213 Longevity regulating pathway - multiple species
    101386334 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101386334 (IGF1)
   05202 Transcriptional misregulation in cancer
    101386334 (IGF1)
   05205 Proteoglycans in cancer
    101386334 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    101386334 (IGF1)
   05218 Melanoma
    101386334 (IGF1)
   05215 Prostate cancer
    101386334 (IGF1)
   05224 Breast cancer
    101386334 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    101386334 (IGF1)
   05414 Dilated cardiomyopathy
    101386334 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101386334 (IGF1)
   01522 Endocrine resistance
    101386334 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:oro04052]
    101386334 (IGF1)
Cytokines and neuropeptides [BR:oro04052]
 Cytokines
  Growth factors (RTK binding)
   101386334 (IGF1)
SSDB
Motif
Pfam: Insulin DUF2865
Other DBs
NCBI-GeneID: 101386334
NCBI-ProteinID: XP_004413236
UniProt: A0A2U3WUV7
LinkDB
Position
Unknown
AA seq 187 aa
MGKISSLPTQLFKCCFCDFLKVKMHIMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKAQKYHPPSTTKKTKSQRRRKGGPKKRPGGEQKVGTEASQQMKGKKKEQR
RETGARN
NT seq 564 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtaaagatgcacatcatgtcctcctcccatctcttctacctggccctgtgcttgctc
accttcaccagctctgccacagctggaccggagacgctctgtggggctgagttggtggac
gctcttcagttcgtgtgtggagacaggggtttttatttcaacaagcccacggggtatggc
tccagcagtcggagggcacctcagacaggcatcgtggacgagtgctgcttccggagctgt
gatttgaggaggctagagatgtactgcgcacccctcaagcctgccaagtctgcccgctca
gtccgtgcccagcgccacactgacatgcccaaggctcagaagtatcatcccccatctacc
accaagaaaacgaagtctcagaggagaaggaaaggtgggccaaagaaacgcccaggaggg
gaacagaaggtggggacggaagcaagtcagcagatgaaaggaaagaagaaagagcagaga
agggagactggagctagaaactga

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