Onychostruthus taczanowskii (white-rumped snowfinch): 121339090
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Entry
121339090 CDS
T07590
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
otc
Onychostruthus taczanowskii (white-rumped snowfinch)
Pathway
otc00270
Cysteine and methionine metabolism
otc00480
Glutathione metabolism
otc01100
Metabolic pathways
otc01240
Biosynthesis of cofactors
otc04216
Ferroptosis
Module
otc_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
otc00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
121339090 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
121339090 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
121339090 (GCLC)
Enzymes [BR:
otc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
121339090 (GCLC)
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Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
121339090
NCBI-ProteinID:
XP_041266533
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All DBs
Position
Unknown
AA seq
636 aa
AA seq
DB search
MGLLSQGSPLSWEETRRYAEHVRRHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRVLLCGEEVLQTLQDKGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTLPDCMPTPVEGGASKSLFFPDEAI
NKHPRFGTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNAVLDGCGSAQNGTGTDTEEYTLMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEINY
SLMWKCNQIAQGQAECPELLGVGFNKKQSGNKTDSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctaagctgggaggagacgcggcggtacgcggag
cacgtgcggcggcacggcatcctccagttcctccacatctaccgcgccctgcgcgaccgc
cacaaggacgtgctcaagtggggcgacgaggtggaatatatgttggtaaaatttgaccat
gaaaataagaaagtgcgtgtgttactctgtggtgaagaagttcttcaaacactgcaagat
aagggggagaagataaatcccaatcacccaacactctggagaccagaatatggaagttac
atgattgagggtacacctggacagccatatgggggaaccatgtctgaattcaacactgtg
caagacaacatgaggaaaagacggcaggaggctgcttctgtactcaaagaaaatgaggct
gtttgtaccgtgacatcatttccaaggttaggctgtcctggatttacactgccggattgt
atgccaacaccagtagaaggaggagcttcaaaatcccttttttttccagatgaagccatc
aataaacatcctagatttggtacactgaccagaaacattcgacaccgaagaggagagaag
gttgtgataaatgtaccaatatttaaagataagaacacaccatcacctttcattgaaaca
tttcctaatgatgatggagaagcagcaaaggcagctaagccagactacatatatatggat
gctatgggttttggaatgggaaactgctgtctccaggtaacttttcaggcttgcagcatt
tccgaagcaaggtatctctatgatcagctagctacgatttgtcccattgtgatggcgttg
agtgctgcgtctccattctacagaggctacgtgtctgacattgactgtcgctggggagtg
atctccgcttccgtggacgatcgaacgcgcgaggagcgagggctggagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagaccca
ttgactttgtttgaggagaaaatacatctagatgatgcaaatgaatccgaccattttgag
aatattcagtctacaaactggcagacaatgaggtttaagccaccacctccaaattcagat
attggatggagagtggaattcagacctatggaggtccagttaacagactttgagaactct
gcttatgttgtgtttgtggtattgctaaccagagtgattctgtcatataaactggacttt
ctcattcctttgtccaaggtggatgaaaacatgaaggtggcccagaaaagagatgctgta
cgacagggaatgttttacttcagaaaagatatatgcaaaggtggaaatgctgttttggat
ggatgtggctctgcacagaatgggacaggcactgacacagaagagtacaccttaatgagc
attgacacaattatcaatgggaaggaaggagtctttcctggtttgatcccaattttgaat
tcctatcttgaaaacatggaagtggatgtggatacaagatgcaccatcctaaactatctg
aagctaatcaaaaagagagcctctggagaattaatgacagttgctcgatggatgagggaa
ttcatcgcacagcatccggactacaagcaggacagtgtgataactgatgaaattaattac
agccttatgtggaagtgcaaccaaatcgctcaaggccaggcagagtgtcctgaactattg
ggggtaggatttaataagaaacaaagtggaaataaaactgactctttgtaa
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