Oncorhynchus tshawytscha (Chinook salmon): 112224639
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Entry
112224639 CDS
T05605
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
otw
Oncorhynchus tshawytscha (Chinook salmon)
Pathway
otw00270
Cysteine and methionine metabolism
otw00480
Glutathione metabolism
otw01100
Metabolic pathways
otw01240
Biosynthesis of cofactors
otw04216
Ferroptosis
Module
otw_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
otw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
112224639 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
112224639 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
112224639 (gclc)
Enzymes [BR:
otw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
112224639 (gclc)
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Motif
Pfam:
GCS
GCS2
HasA
Motif
Other DBs
NCBI-GeneID:
112224639
NCBI-ProteinID:
XP_024244084
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Position
LG25:34634456..34642376
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AA seq
630 aa
AA seq
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MGLLSKGSPLNWEETKKYADHVRKHGIVQFLNIYNKVKERQKDVLLWGDEVEYMLIEMDE
KNGKVRLVLNGGEVLETLQDKGEKTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMGKRRREASSVLNKNETLATITSFPRLGCPGFTQPEYKPTPVEKGVSKSLFFPDEAI
NQHPRFSTLTRNIRHRRGEKVVINVPIFKDKCTPSPFVEKFPEDDGEAARAALPDHIYMD
AMGFGMGNCCLQVTFQACSIEEARYLYDQLATFCPIMMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTGEERGLEPLKTNKFRILKSRYDSIDSYLSSCGDRYNDIDLTIDEEINKQLL
DAGIDKLLAQHIAHLFIRDPLSLFEEKIYLDDENESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAFVVFIVLLTRVILSYKLDFLIPLSKVDENMKAAQKRNAV
QEGMFYFRKDIYKGCNPALDSSSSAAQNGLDSEGDNEYTLMSIDTIINGKEGIFQGLIPI
LNCYLENMEVDVDTRCTILNYLKLIKRRASGELMTMAKWMREFVDKHPQYKQDSVITDRI
NYDLLRKCDSITKGEERCPELIGDPVNRGK
NT seq
1893 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcaaaagggtcaccgctcaactgggaagaaaccaaaaagtatgcagac
catgttcggaaacatggcatcgttcagtttctcaacatctataacaaggtgaaagaacga
cagaaagatgtcttattatggggcgatgaggtggaatacatgttgatcgaaatggatgag
aaaaatggaaaggtccgtcttgttctcaatggtggggaggttttggaaacccttcaagac
aaaggagaaaagactaaccccaaccatcctaccctttggaggccagagtatggcagctac
atgatcgaagggactccggggcagccctatggtgggacgatgtcagagttcaacacagtg
gaggacaacatggggaagcgaaggcgagaggcctcatctgtgctaaataagaatgaaacg
cttgccaccatcacgtcattcccaaggttaggctgcccaggcttcacacagccagaatac
aagccaacacctgttgaaaagggagtgtcaaaatcactgttcttcccagatgaagccata
aaccaacacccaagattcagcaccctgactagaaacattcgtcacagaagaggagagaag
gtggtgatcaacgtacccatctttaaagacaaatgcaccccatctccatttgtggagaag
tttccggaagatgatggggaggctgccagggcagctctacctgatcacatctacatggat
gccatgggatttggaatgggcaattgctgtcttcaggtgacattccaagcttgcagcatt
gaagaggcgaggtacctttatgaccaactagcaacattctgccctataatgatggccctc
agtgctgcttcgccgttctacagaggctatgtgtcagacattgattgtcgctggggagtt
atttctgcctcggtagatgacaggactggggaagagagggggctggagcctttgaaaacc
aacaaatttcgaatcttgaaatccagatatgattcaatcgacagctacctctccagctgt
ggcgataggtacaatgacatagatctgacaatagatgaggagatcaacaaacagctgctg
gatgcagggatcgacaaactgctggcccaacacatagcccatctcttcattcgggatccg
ctctcactatttgaagagaaaatttacttggatgatgaaaacgagtctgatcactttgag
aatctgcagtcaaccaactggcagacaatgaggttcaaacctcctcctccaaactcggac
atcggatggcgagttgagttccgtcccatggaggtgcaacttaccgattttgaaaactct
gcatttgttgttttcatcgtcctgctcaccagggttatactgtcctataaactggacttt
ctcatccccttgtcaaaggttgatgaaaacatgaaagctgcccagaaaagaaatgcagtc
caagagggcatgttttacttccggaaggacatctataaaggctgcaaccctgccctcgat
agctcctcatcggctgcccagaatggcttggacagtgagggtgacaatgagtacacactg
atgagcattgacacaatcatcaatggaaaggaaggaatttttcaagggttgataccaatc
ctcaactgctacctagaaaacatggaggtggatgttgatacaagatgcaccatcctgaac
tacctgaagctcatcaagagacgtgcctccggtgaactgatgaccatggctaaatggatg
agggagtttgtggacaagcacccccaatacaagcaagacagtgtcataactgacagaatc
aactacgacctactccgcaagtgtgacagcatcacaaaaggagaggagcgatgcccagaa
cttattggtgacccagtcaatcggggcaaatga
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