KEGG   Odocoileus virginianus (white-tailed deer): 110124597
Entry
110124597         CDS       T10722                                 
Symbol
NOS3
Name
(RefSeq) LOW QUALITY PROTEIN: nitric oxide synthase 3
  KO
K13242  nitric-oxide synthase, endothelial [EC:1.14.13.39]
Organism
ovr  Odocoileus virginianus (white-tailed deer)
Pathway
ovr00220  Arginine biosynthesis
ovr00330  Arginine and proline metabolism
ovr01100  Metabolic pathways
ovr04020  Calcium signaling pathway
ovr04022  cGMP-PKG signaling pathway
ovr04066  HIF-1 signaling pathway
ovr04071  Sphingolipid signaling pathway
ovr04151  PI3K-Akt signaling pathway
ovr04370  VEGF signaling pathway
ovr04371  Apelin signaling pathway
ovr04611  Platelet activation
ovr04915  Estrogen signaling pathway
ovr04921  Oxytocin signaling pathway
ovr04926  Relaxin signaling pathway
ovr04931  Insulin resistance
ovr04933  AGE-RAGE signaling pathway in diabetic complications
ovr05415  Diabetic cardiomyopathy
ovr05417  Lipid and atherosclerosis
ovr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ovr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00220 Arginine biosynthesis
    110124597 (NOS3)
   00330 Arginine and proline metabolism
    110124597 (NOS3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04370 VEGF signaling pathway
    110124597 (NOS3)
   04371 Apelin signaling pathway
    110124597 (NOS3)
   04066 HIF-1 signaling pathway
    110124597 (NOS3)
   04020 Calcium signaling pathway
    110124597 (NOS3)
   04071 Sphingolipid signaling pathway
    110124597 (NOS3)
   04022 cGMP-PKG signaling pathway
    110124597 (NOS3)
   04151 PI3K-Akt signaling pathway
    110124597 (NOS3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110124597 (NOS3)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    110124597 (NOS3)
   04921 Oxytocin signaling pathway
    110124597 (NOS3)
   04926 Relaxin signaling pathway
    110124597 (NOS3)
 09160 Human Diseases
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110124597 (NOS3)
   05418 Fluid shear stress and atherosclerosis
    110124597 (NOS3)
   05415 Diabetic cardiomyopathy
    110124597 (NOS3)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    110124597 (NOS3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    110124597 (NOS3)
Enzymes [BR:ovr01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.13  With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.13.39  nitric-oxide synthase (NADPH)
     110124597 (NOS3)
SSDB
Motif
Pfam: NO_synthase FAD_binding_1 Flavodoxin_1 NAD_binding_1
Other DBs
NCBI-GeneID: 110124597
NCBI-ProteinID: XP_070310991
LinkDB
Position
1:complement(6081921..6099987)
AA seq 1205 aa
MGNLKSVGQEPGPPCGLGLGLGLGLCGKQGPASPAPEPSRAPAPTTPHTPDHSPAPSSPT
LTRPPEGPKFPRVKNWELGSITYDTLCAQAQQDGPCTPRRCLGSLVLPRKLQTRPSQGPP
PAEQLLSQARDFINQYYSSIKRSGSQAHEERLQEVEAEVASTGTYHLRESELVFGAKQAW
RNAPRCVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYATNRGNLRSAITVFPQRAPGR
GDFRIWNSQLVRYAGYRQQDGSVRGDPANVEITELCVQHGWTPGNGRFDVLPLLLQAPDE
APELFVLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFPAAPFSGWYM
STEIGTRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSYQLAKVTIV
DHHAATVSFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYVLSPAFHYQPD
PWKGSSAKGTGITRKKTFKEVANAVKISASLMGTLMAKRVKATILYASETGRAQSYAQQL
GRLFRKAFDPRVLCMDAYDVVSLEHEALVLVVTSTFGNGDPPENGESFAAALMEMSGPYN
SSPRPEQHKSYKIRFNSVSCSDPLVSSWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYP
HFCAFARAVDTRLEELGGERLLQLGQGDELCGQEEAFRGWAKAAFQASCETFCVGEEAKA
AAQDIFSPKRSWKRQRYRLSAQAEGLQLLPGLVHVHRRKMFQATVLSVENLQSSKSTRAT
ILVRLDTAGQEGLQYQPGDHIGICPPNRPGLVEALLSRVEDPPPPAESVAVEQLEKGSPG
GPPPSWVRDPRLPPCTLRQALTFFLDITSPPSPRLLRLLSTLAEEPSEQQELETLSQDPR
RYEEWKWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRYYSVSSAPSAHPGEVHLTVA
VLAYRTQDGLGPLHYGVCSTWLSQLKTGDPVPCFIRGAPSFRLPPDPYVPCILVGPGTGI
APFRGFWQERLHDIESKGLQPAPMTLVFGCRCSQLDHLYRDEVQDAQQRGVFGRVLTAFS
REPDSPKTYVQDILRTELAAEVHRVLCLERGHMFVCGDVTMATSVLQTVQRILATEGDME
LDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERHLRGAVPWAFDPPGP
DTPGP
NT seq 3618 nt   +upstreamnt  +downstreamnt
atgggcaacttgaagagcgtgggccaggagcccgggcccccctgcggcctggggctgggg
ctgggccttgggctgtgcggcaagcagggcccagcctcccctgcaccggagcccagccgg
gcccccgcacccaccaccccgcacacaccagaccacagcccagctcccagcagccccacg
ctgacccggcctccggaggggcccaagttccctcgcgtgaagaactgggagctggggagc
atcacctacgacactctatgcgcacaggcccagcaggacgggccctgcacccccagacgc
tgcctgggctccctggtgttgccccggaaactgcagacccggccctcccagggacctcca
cctgctgagcagctgctgagccaggccagggacttcatcaaccagtactacagctccatc
aagaggagcggctcccaggctcacgaggagcgccttcaggaggtggaggccgaggtggca
tccacaggcacctaccacctgcgagagagcgagctggtgttcggggccaagcaggcctgg
cgcaatgcaccccgctgtgtgggccgcatccagtgggggaagctgcaggtgttcgatgcc
cgggactgcagctcagcacaggagatgttcacctacatctgcaaccacatcaagtacgcc
accaaccgcggcaaccttcgctcggccatcacagtgttcccgcagcgcgccccgggccgc
ggagacttccggatctggaacagccagctggtgcgctacgcgggctatagacagcaggac
ggctccgtgcgcggggacccggccaacgtggagatcacggagctctgcgtccagcatggc
tggacccctggaaatggccgcttcgacgtgctgcccctgctgctccaggccccagacgag
gctccggagctctttgttctgccccccgagctggtccttgaagtgcccctggagcacccc
acactggagtggttcgcggccctgggcctgcgctggtatgccctcccggccgtgtccaac
atgctgctggaaattgggggtctggagttccccgcggcccctttcagcggctggtacatg
agcacggagatcggcacgcggaacctgtgtgaccctcaccgctacaacatcctggaggat
gtggccgtctgcatggacctcgacacccggaccacctcgtccctgtggaaggacaaggcg
gccgtggaaatcaacctggctgtgctccacagctatcagctcgccaaggtgaccatcgtg
gaccaccatgccgccactgtgtccttcatgaagcacctggagaacgagcagaaggccagg
gggggctgccccgccgactgggcctggatcgtgccccccatctccggcagcctcacgccc
gtcttccaccaggagatggtcaactacgtcctgtcccctgccttccactatcagccagat
ccttggaaggggagctcagccaagggcaccggcatcaccaggaagaagacctttaaggaa
gtggccaatgcggtgaagatctctgcctcactcatgggcaccctgatggccaagcgagtg
aaggcgaccatcctatacgcctctgagaccggccgggcccagagctacgctcagcagctg
gggaggctcttccggaaggccttcgacccccgggtcctgtgcatggatgcatatgacgtg
gtgtccctggagcacgaggcgctggtgctggtagtgaccagcaccttcgggaacggcgac
cccccggagaacggagagagttttgcagctgcactgatggagatgtcagggccctacaac
agctccccaaggccagaacagcacaagagttacaagatccgcttcaacagcgtctcctgc
tcagacccgctggtgtcctcctggcggcggaagagaaaggagtccagcaacacggacagc
gcgggggcactggggaccctcaggttctgtgtgtttggactgggctcccgggcatacccc
cacttctgcgccttcgcacgagcggtagacacccgactggaagagctgggaggggagcgg
ctgctgcagctgggccagggcgacgagctctgtggccaggaggaggccttccgtggttgg
gcaaaggcggccttccaggcctcctgtgagacgttctgcgtcggggaggaggccaaggcc
gctgcccaggacatcttcagccccaaacggagctggaaacgccagaggtaccggctgagc
gcccaggcagagggcctccagctgctgccaggcctggtccacgtgcacagacggaagatg
tttcaggccacagtcctctcagtggaaaacctgcaaagcagcaagtccacccgggccacc
atcctggtgcgcctggacactgcaggccaggaggggctgcagtaccagccgggggaccac
ataggcatctgcccgcccaaccggcccggcctcgtggaggcgctgctgagccgcgtggag
gacccaccgccgcccgccgagtctgtggccgtggagcagctggaaaagggcagcccaggc
ggcccgcctcccagctgggtgcgggacccacggctgcccccgtgcacgctgcgccaggct
ctcaccttcttcctggacatcacctccccgcccagcccccggcttctccgactgctcagc
accctggctgaagaacccagtgagcagcaggagctcgagaccctcagtcaggacccccgg
cgctacgaggagtggaagtggttccgctgccccacgctgctggaggtgctggagcagttc
ccgtctgtggcactgcccgccccgctgctcctcacccagctgcccctgctgcagcccagg
tactactccgtcagctcggcccccagcgcccaccccggagaggtccacctcacagtggcc
gtgctggcgtacaggacccaagacgggctgggccccctacactacggggtctgctccacg
tggctgagccagctcaagactggagaccccgtgccctgctttatcaggggggctccctcc
ttccggctgccacctgacccctacgtgccctgcatcctcgtgggccccggcactggcatt
gcccccttccggggattttggcaggagaggctgcatgacattgagagcaaaggtctgcag
cccgcccccatgaccctggtgttcgggtgccggtgctcccagctcgaccatctctaccgc
gacgaggtgcaggacgcccagcagcgcggggtgtttggccgcgtcctcaccgccttctcc
cgggaacctgacagccccaagacctacgtacaggacatcctgaggaccgagctggctgcc
gaggtgcaccgcgtgctgtgcctcgagcggggccacatgtttgtctgcggcgacgtcact
atggcaaccagcgtcctgcagacggtgcagcgcatcttggcgacagagggcgacatggag
ctggacgaggccggcgacgtcatcggcgtgctgcgggatcagcaacgctatcacgaggac
attttcggcctcacgctgcgcacccaggaggtgacaagccgcatacgcacccagagcttt
tccctgcaggagcggcatctgcggggcgcagtgccctgggccttcgacccgcccggccca
gacacccccggcccctga

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