KEGG   Odocoileus virginianus (white-tailed deer): 110130210
Entry
110130210         CDS       T10722                                 
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
  KO
K04441  p38 MAP kinase [EC:2.7.11.24]
Organism
ovr  Odocoileus virginianus (white-tailed deer)
Pathway
ovr01522  Endocrine resistance
ovr04010  MAPK signaling pathway
ovr04015  Rap1 signaling pathway
ovr04068  FoxO signaling pathway
ovr04071  Sphingolipid signaling pathway
ovr04114  Oocyte meiosis
ovr04148  Efferocytosis
ovr04218  Cellular senescence
ovr04261  Adrenergic signaling in cardiomyocytes
ovr04370  VEGF signaling pathway
ovr04380  Osteoclast differentiation
ovr04517  IgSF CAM signaling
ovr04550  Signaling pathways regulating pluripotency of stem cells
ovr04611  Platelet activation
ovr04613  Neutrophil extracellular trap formation
ovr04620  Toll-like receptor signaling pathway
ovr04621  NOD-like receptor signaling pathway
ovr04622  RIG-I-like receptor signaling pathway
ovr04625  C-type lectin receptor signaling pathway
ovr04657  IL-17 signaling pathway
ovr04658  Th1 and Th2 cell differentiation
ovr04659  Th17 cell differentiation
ovr04660  T cell receptor signaling pathway
ovr04664  Fc epsilon RI signaling pathway
ovr04668  TNF signaling pathway
ovr04670  Leukocyte transendothelial migration
ovr04714  Thermogenesis
ovr04722  Neurotrophin signaling pathway
ovr04723  Retrograde endocannabinoid signaling
ovr04728  Dopaminergic synapse
ovr04750  Inflammatory mediator regulation of TRP channels
ovr04912  GnRH signaling pathway
ovr04914  Progesterone-mediated oocyte maturation
ovr04917  Prolactin signaling pathway
ovr04926  Relaxin signaling pathway
ovr04932  Non-alcoholic fatty liver disease
ovr04933  AGE-RAGE signaling pathway in diabetic complications
ovr04935  Growth hormone synthesis, secretion and action
ovr04936  Alcoholic liver disease
ovr05014  Amyotrophic lateral sclerosis
ovr05020  Prion disease
ovr05022  Pathways of neurodegeneration - multiple diseases
ovr05132  Salmonella infection
ovr05133  Pertussis
ovr05135  Yersinia infection
ovr05140  Leishmaniasis
ovr05142  Chagas disease
ovr05145  Toxoplasmosis
ovr05152  Tuberculosis
ovr05161  Hepatitis B
ovr05163  Human cytomegalovirus infection
ovr05167  Kaposi sarcoma-associated herpesvirus infection
ovr05169  Epstein-Barr virus infection
ovr05170  Human immunodeficiency virus 1 infection
ovr05171  Coronavirus disease - COVID-19
ovr05205  Proteoglycans in cancer
ovr05208  Chemical carcinogenesis - reactive oxygen species
ovr05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ovr05415  Diabetic cardiomyopathy
ovr05417  Lipid and atherosclerosis
ovr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ovr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110130210 (MAPK12)
   04015 Rap1 signaling pathway
    110130210 (MAPK12)
   04370 VEGF signaling pathway
    110130210 (MAPK12)
   04668 TNF signaling pathway
    110130210 (MAPK12)
   04068 FoxO signaling pathway
    110130210 (MAPK12)
   04071 Sphingolipid signaling pathway
    110130210 (MAPK12)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    110130210 (MAPK12)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    110130210 (MAPK12)
  09143 Cell growth and death
   04114 Oocyte meiosis
    110130210 (MAPK12)
   04218 Cellular senescence
    110130210 (MAPK12)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    110130210 (MAPK12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110130210 (MAPK12)
   04613 Neutrophil extracellular trap formation
    110130210 (MAPK12)
   04620 Toll-like receptor signaling pathway
    110130210 (MAPK12)
   04621 NOD-like receptor signaling pathway
    110130210 (MAPK12)
   04622 RIG-I-like receptor signaling pathway
    110130210 (MAPK12)
   04625 C-type lectin receptor signaling pathway
    110130210 (MAPK12)
   04660 T cell receptor signaling pathway
    110130210 (MAPK12)
   04658 Th1 and Th2 cell differentiation
    110130210 (MAPK12)
   04659 Th17 cell differentiation
    110130210 (MAPK12)
   04657 IL-17 signaling pathway
    110130210 (MAPK12)
   04664 Fc epsilon RI signaling pathway
    110130210 (MAPK12)
   04670 Leukocyte transendothelial migration
    110130210 (MAPK12)
  09152 Endocrine system
   04912 GnRH signaling pathway
    110130210 (MAPK12)
   04914 Progesterone-mediated oocyte maturation
    110130210 (MAPK12)
   04917 Prolactin signaling pathway
    110130210 (MAPK12)
   04926 Relaxin signaling pathway
    110130210 (MAPK12)
   04935 Growth hormone synthesis, secretion and action
    110130210 (MAPK12)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110130210 (MAPK12)
  09156 Nervous system
   04728 Dopaminergic synapse
    110130210 (MAPK12)
   04723 Retrograde endocannabinoid signaling
    110130210 (MAPK12)
   04722 Neurotrophin signaling pathway
    110130210 (MAPK12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    110130210 (MAPK12)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    110130210 (MAPK12)
  09159 Environmental adaptation
   04714 Thermogenesis
    110130210 (MAPK12)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    110130210 (MAPK12)
   05208 Chemical carcinogenesis - reactive oxygen species
    110130210 (MAPK12)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    110130210 (MAPK12)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110130210 (MAPK12)
   05161 Hepatitis B
    110130210 (MAPK12)
   05171 Coronavirus disease - COVID-19
    110130210 (MAPK12)
   05163 Human cytomegalovirus infection
    110130210 (MAPK12)
   05167 Kaposi sarcoma-associated herpesvirus infection
    110130210 (MAPK12)
   05169 Epstein-Barr virus infection
    110130210 (MAPK12)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    110130210 (MAPK12)
   05135 Yersinia infection
    110130210 (MAPK12)
   05133 Pertussis
    110130210 (MAPK12)
   05152 Tuberculosis
    110130210 (MAPK12)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110130210 (MAPK12)
   05140 Leishmaniasis
    110130210 (MAPK12)
   05142 Chagas disease
    110130210 (MAPK12)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    110130210 (MAPK12)
   05020 Prion disease
    110130210 (MAPK12)
   05022 Pathways of neurodegeneration - multiple diseases
    110130210 (MAPK12)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110130210 (MAPK12)
   05418 Fluid shear stress and atherosclerosis
    110130210 (MAPK12)
   05415 Diabetic cardiomyopathy
    110130210 (MAPK12)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110130210 (MAPK12)
   04932 Non-alcoholic fatty liver disease
    110130210 (MAPK12)
   04933 AGE-RAGE signaling pathway in diabetic complications
    110130210 (MAPK12)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    110130210 (MAPK12)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ovr01001]
    110130210 (MAPK12)
Enzymes [BR:ovr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     110130210 (MAPK12)
Protein kinases [BR:ovr01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   110130210 (MAPK12)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Kdo Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 110130210
NCBI-ProteinID: XP_020737667
UniProt: A0A6J0WIT9
LinkDB
Position
23:complement(16144292..16152762)
AA seq 367 aa
MSSPSPARKGFYRQEVTKTAWEVRVVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRVQFLVYQMLKGLKYIHAAGVIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMHYTQTVDIWSVGCIMAEMITGKTLFKGNDHLDQLKEIMK
VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASVLTNASPLAVSLLEKMLVLDAERRV
TAAEALAHPYFESLHDMEDEPQAQKYDESFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAK
VSKETAL
NT seq 1104 nt   +upstreamnt  +downstreamnt
atgagctctccgtcgcccgcccgcaagggcttttatcgccaggaggtgaccaagacggcc
tgggaggtgcgcgtcgtgtaccaggatctgcagcccgtgggctcgggcgcctatggtgcc
gtgtgctcggcagtggacagccgcactggcgccaaggtggccatcaagaagctgtaccgg
ccctttcagtccgagctgttcgccaagcgcgcctaccgcgagcttcgcctgctgaagcac
atgcgccacgagaacgtgattgggctgctggatgtgttcacgcctgacgagacactggat
gacttcacagacttctacctggtgatgccgttcatgggcaccgacttgggaaagctcatg
aagcatgagaagctgagtgaggaccgagtgcagttccttgtctaccagatgcttaagggg
ctgaagtacatccacgctgctggcgtcatccacagggacctgaagcctggcaacctggcg
gtgaacgaggactgtgagctgaagatcctggacttcggcctggcccggcaggcagacagc
gagatgaccgggtacgtggtgacccggtggtaccgggcacccgaagtcatcttgaactgg
atgcactacacgcagacggtggacatctggtccgtgggctgcatcatggccgagatgatc
acggggaagacgctcttcaaaggcaacgaccacctggaccagctgaaggagatcatgaag
gtgacggggacgcctcccgcggagtttgtgcagaggctgcaaagtgacgaggccaagaac
tacatgaagggcctccctgagctggagaagaaggattttgcctccgtcctgaccaacgcg
agccccctggccgtgagcctcctggagaagatgctggtgctggatgcggagcggcgggtg
acggcggccgaggcgctggcccacccctacttcgagtctctgcacgacatggaggacgag
ccccaggcccagaaatacgacgagtcctttgacgacgtggaccgcacgctggacgagtgg
aagcgtgtcacatataaagaggtgctcagcttcaagcctccccggcagctgggggccaag
gtctccaaggagacagccttgtga

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