Odocoileus virginianus (white-tailed deer): 110136760
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Entry
110136760 CDS
T10722
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
ovr Odocoileus virginianus (white-tailed deer)
Pathway
ovr00230
Purine metabolism
ovr00670
One carbon pool by folate
ovr01100
Metabolic pathways
ovr01523
Antifolate resistance
Module
ovr_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ovr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
110136760 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
110136760 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
110136760 (GART)
Enzymes [BR:
ovr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
110136760 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
110136760 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
110136760 (GART)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_C
AIRS
ATP-grasp_3
ATP-grasp_4
Dala_Dala_lig_C
DUF6365
Motif
Other DBs
NCBI-GeneID:
110136760
NCBI-ProteinID:
XP_020748282
UniProt:
A0A6J0XEP8
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Position
25:complement(50693256..50720672)
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AA seq
873 aa
AA seq
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MSADFPALVVKASGLAAGKGVIVAKSKEEACEAVREIMQGKAFGEAGETVVIEELLEGEE
VSCLCFTDGRTVAPMPPAQDHKRLLEGDQGPNTGGMGAYCPAPQVSKDLLLKIKNTILQR
TVNGMQEEGMPYTGILYAGIMLTKSGPKVLEFNCRFGDPECQVILPLLKSDLYEVIQSTL
DGLLCTSLPVWLDNCAAVTVVMASKGYPGDYSKGVEITGFPEAQALGLEVFQAGTALKDG
KVVTNGGRVLTVTAIRGNLISALEEARKGLAAIKFEGAVYRKDIGFRAIAFLQQPRGLTY
KESGVDIAAGNMLVQKIKPLAKATSRPGCDVDLGGFAGLFDLKAAGFTDPLLACGADGVG
TKLKIAQQCNKHDTIGQDLVAMCVNDILAQGAEPLFFLDYFSCGKLDLRVTEAVIAGIAQ
ACRKAGCALLGGETAEMPDMYAPGEYDLAGFAIGAMERDQKLPHLERITEGDVVIGIASS
GLHSNGFSLVRKIVAKSSLRYSSPAPDGCGNQTLGDLLLTPTRIYSHSLLPVLRSGRVKA
VAHITGGGLLENIPRVLPQKLGVNLDAQTWRVPRIFSWLQQEGHLSEEEMAKTFNCGIGA
ALVVSENLVKQTLQDIEQHQEEAWVIGRVVACPEGSPRVKVEHLIETMQINGSVLENGTL
KNHFSVQPKKARVAVLISGTGSNLQALIDSTREPSSLADIVVVISNKAAVAGLDKAEKAG
IPTRVINHKLYKNREAFDTAVDEVLEEFSTDIVCLAGFMRILSGSFVRKWNGKMLNIHPS
LLPSFKGSNAHEQVLDAGVTITGCTVHFVAEDVDAGQIILQEAVPVKRGDTVESLSERVK
LAEHKIFPSALQLVASGAVRLGENGKICWVKEE
NT seq
2622 nt
NT seq
+upstream
nt +downstream
nt
atgagtgcagacttccccgctttggttgtgaaggccagtgggcttgcagctgggaaaggg
gtaattgttgccaagagcaaagaggaggcctgtgaagctgtcagggagattatgcagggt
aaagcttttggagaagcaggagaaacagttgtcattgaagaacttcttgaaggagaagag
gtgtcttgtctgtgcttcactgatggacggactgtggcccccatgccaccagcacaggac
cataagcgactgctggagggcgatcagggccccaacactgggggaatgggcgcctactgt
ccagcccctcaggtttctaaggatttgttgctaaaaattaaaaataccatccttcagagg
acagtgaatggcatgcaagaggagggtatgccatacacaggtatcctctatgctggtata
atgttgaccaagagcggccccaaagttctggagtttaattgccgtttcggtgatccagag
tgccaagtgatcctcccacttcttaaaagtgatctttatgaagtgatccagtctacctta
gatggcctgctctgcacatctctgcctgtttggctggacaactgtgctgccgtaactgtg
gtcatggcaagtaaaggttatccaggagactacagcaagggtgtagagataacagggttt
cctgaggctcaggctttaggactggaggtgttccaagcaggcactgccctaaaagatggc
aaggtggtgactaacgggggtagggtccttactgtcacggccatcaggggaaatctcatc
tcagcccttgaagaagccaggaaaggacttgctgctataaagtttgagggagctgtttat
aggaaagacatcggctttcgagccatagctttcctccaacaacccaggggcctgacttac
aaggaatctggggtagacattgcagctggtaatatgttggtccagaaaattaaaccttta
gcaaaggccacctccagaccaggctgtgatgttgatctcggaggttttgctggtcttttt
gacctgaaagcagctggtttcactgatcctcttctggcctgtggagcagatggtgttggg
acgaaactgaagattgcccagcagtgcaataaacatgacaccattggtcaggatttggtt
gcaatgtgtgtaaatgacattcttgcgcaaggagcagagcccctctttttccttgattac
ttctcctgtggaaaacttgacctccgtgtgactgaagctgtcatcgctgggatcgcccaa
gcttgtagaaaggctggatgcgctctcctcggaggtgaaacggcagagatgcctgacatg
tatgctcctggagagtatgatctagctggttttgccattggcgccatggagcgggatcag
aaacttcctcacctggaaagaatcacggaaggggatgttgttattggcattgcttcatct
ggtcttcacagcaatggattcagccttgtgaggaaaattgtagcaaaatcttccctccga
tactcttctccagcacctgatggctgtggtaaccagaccttaggtgacttacttctaacc
ccaaccagaatctacagccactcactgttacctgtcctacgttcaggacgtgttaaggct
gttgcgcatattactggtggaggattactggaaaacatccccagagtcctccctcagaaa
ttgggggtgaatttagatgcccagacctggagggtccccaggatcttctcatggttacag
caggaaggccacctctctgaagaggagatggccaaaacatttaactgtgggattggggct
gccctcgtggtatcggagaacctggtgaagcagactctgcaggatattgagcagcaccag
gaagaagcctgggtgatcggcagagtggttgcgtgtcccgaaggttctcctcgtgtgaaa
gtcgagcatctgattgaaaccatgcaaataaatggatcagtattggagaatggaaccctg
aaaaatcatttctctgttcaaccaaaaaaggcaagagtagctgtcttaatttctgggaca
ggatcaaacctccaagctctcatagacagcactagggagccaagtagtttggcagacatt
gttgttgtgatctccaacaaagctgcagtggctggcttagataaagcagaaaaagccgga
attcccaccagagtaattaatcataaattatataaaaatcgtgaagcatttgacactgca
gttgacgaagtccttgaagagttctccacagacatagtctgtcttgcaggattcatgaga
attttgtctggctccttcgtcagaaaatggaatgggaaaatgctcaatatccacccatcc
ttgctcccttcatttaagggttcaaatgcccatgaacaagttctggacgctggggtcaca
atcaccgggtgcactgtgcactttgtagctgaagatgtagatgccggtcaaattatctta
caggaagccgttccagtgaagaggggtgacactgttgaaagtctatctgagagagtaaaa
ttagcggaacataaaatatttccctcagccctccagctggtggccagtggagctgtacgg
cttggagaaaatggcaaaatctgttgggtcaaagaggaatga
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