Odocoileus virginianus (white-tailed deer): 110139341
Help
Entry
110139341 CDS
T10722
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2 isoform X1
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
ovr Odocoileus virginianus (white-tailed deer)
Pathway
ovr05012
Parkinson disease
ovr05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
ovr00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
110139341 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
110139341 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ovr01001
]
110139341 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ovr04131
]
110139341 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ovr04147
]
110139341 (LRRK2)
Enzymes [BR:
ovr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
110139341 (LRRK2)
Protein kinases [BR:
ovr01001
]
Serine/threonine kinases: TKL group
LRRK family
110139341 (LRRK2)
Membrane trafficking [BR:
ovr04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
110139341 (LRRK2)
Exosome [BR:
ovr04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
110139341 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_4
LRR_8
Roc
COR
Ras
LRR_14
LRR_9
Arf
WD40_CDC20-Fz
Beta-prop_EML_2
Ank_2
T2SSE
Beta-prop_RSE1_2nd
Kdo
nSTAND3
G-alpha
Beta-prop_RIG_2nd
GTP_EFTU
AAA_22
AAA_16
LRR_6
ABC_tran
PduV-EutP
AAA_7
WD40_Prp19
MobB
NACHT
MMR_HSR1
LRR_13
TrwB_AAD_bind
AAA_29
cobW
FtsK_SpoIIIE
AAA_23
TniB
Arm
Motif
Other DBs
NCBI-GeneID:
110139341
NCBI-ProteinID:
XP_070310670
LinkDB
All DBs
Position
24:complement(37330917..37523292)
Genome browser
AA seq
2527 aa
AA seq
DB search
MASGSSQGCEEDQESLQKLIVRLNNVQEGKQIETLVQTLEDMLVFTYADHASKLFQDKNV
HVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPNTMQSLMGPHDIGHDWEVLGVHQLILK
MLTVHNASVNLTTVGLKALDLLLTSGKITLLILDEENDIFLLIFDAMRTFSASDEVQKLG
CKVLHVLFERVSEEQLTEFVENKDYMILLSALKNFEDEEEIVLHVLHCLHSLAIPCSNVE
VLMSGNVRCYNIVVEAMKAFPISEKIQEVSCCLLHRLTLGNFFNILVLNEVHEFVVKAVQ
QYSENAVLQIAALSCLALLTETIFLNQDLEEKNENQENDDDEEEDKLFWLEACYKALTWH
RKNKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASAN
ALSTLLEQNVNFRKILLSKGIYLNVLELMQKHMHSPEVAESGCKMLNHLFEESSTSLDTM
AAVVPKIITVMKSHETSLSVQLEALRAMLHFIVPGIPEEYREDTEYQHKLNMIEKQCFRN
DIHKLVLAALNRFIGSPGIQKCGLKVISSITHFPDALEVLSLEGAIDSVLHTLQMYPDDQ
EIQCLGLSLIGCLITKKNLCTVTGYLLAKILISTLQRFKDVGEVQIKGFQTVLTILELSV
SFSKLLVHHCFDSVIFHQLSSSIMEQKDQQFLNLCCKCFAKLTIDNELKCVLLEKACDQN
NSIMVECLLLLGADANRAKEATSLICQVCEKASNPKLVELLLNSGSREQDVRKALTISIG
KGNSQIISLLLRRLALDLANNSICLGGFCMGKIEPSWLGPLFPDKTSYLRKETNIGSTLA
RMVLRYQMRSSVEEGAGSGSNGNFSEEMVDKFDEWTFIPESYIDSVFGQSDDLDSEGSEG
SFLVKKKSNSISVGEFYRDPALQRCSPNLQRHSSSLGPIFDHEDLLKRKRKLFSSDDSLR
ASKFQSHMRHSESISSLPSEREYITSLDLSANELRDVDALSQNSCISGHLEHLEKLELHQ
NSLTSFPQQLCETLKCLTHLDLHSNKFTSFPTYLLKMSCIANLDVSRNDIGPSVVLDPAV
TCPTLKQFNLSYNQISSLPANLGDVVEKLEQLILEGNKISEICSPLSLKELKILNLSKNH
ISSLSEDFLETCPKVEILSARMNFLAAMPFLPSSITSLRLSQNRFTCVPEAILHLPHLRS
LDMSSNDIRYLPGPVHWRSLNLRELLFSHNQISILDLSEKACAWSRIEKLHLSHNKLKEI
PPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHVGCKAKDIIR
FLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKIKKSDLGMQGATVGIDVKDWPIQI
RGKGKKDLILNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKA
RASSSPVILVGTHLDVTDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKL
RKTIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPIEFPVIDRKRLLQLVREH
QLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKVMAQILTVKVEGFPK
HPKGIISRRDVEKFLSKKKRFPKNYMAQYFKLLEKFQIALPIGEEYLLVPSSLSDHRPVI
ELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYL
NWSPEAYCLVGSEVLDHHAESFLKITVPSCRKGCVLLGQVVDHIDSLMEEWFPGLLEIDI
CGEGETLLKKWALYSFNDGEEHQKILLDNLMKKAEEGDLLVNPDQPRLTIPISQIAPDLI
LADLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRAAYKGEEVAVKIFNKHTSLRLLRQE
LVVLCHLHHPSLISLLAAGIRPRMLVMELASKGSLDRLLQQDKTSLTRTLQHRIVLHVAD
GLRYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRA
PEVARGNVIYNQQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKEYG
CAPWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMRRISIPKSFTVECMVAMNH
NSKNVRIWLGCGHTDKGQLSCLDLNTERYTSEEVTDSRILCLALVYLPVEKESWIVSGTQ
SGMLLVVNTEDGRKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGTADGNLAIFEDKTV
KCKGATPLKILNIGNVSTPLMCLSESVNLTEKNIMWGGCGTKVFSFSDDFTIQKLIETRT
NQRFSNTSFCDSNIIAVVVDTALYVAKKNSPCVEVWDKKTEKLCELIDCVHFLKEELVRV
SKESKHKMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSTRRIIRIIHNFCDSVRVMMT
AQLGSLKNVMLVLGYNRKSAEGTQHQKEIQSCLSVWDINLPHEVQNLEKHIEVRKELAEK
MRRISVE
NT seq
7584 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagcagccaggggtgcgaggaggaccaggaatctctgcagaagttgata
gttaggctgaacaatgtccaggaaggaaaacagatagagacgctggttcaaaccctggag
gatatgctggtgttcacttacgccgatcacgcctccaagttatttcaagacaaaaatgtc
cacgtgcctctgttgatcgtcttggactcatatatgagagtcgctagtgtgcagcaggtg
ggttggtcacttttatgcaaattaatagaaatctgtccaaatacgatgcaaagcttaatg
ggaccccatgatattggacatgattgggaagtccttggggttcaccagttgattcttaaa
atgctaacagttcataatgccagtgtcaacctgacaacagttggattgaaggccttagat
cttctcctaacttcaggtaaaatcactttgctgatattggatgaagaaaatgatattttc
ttgttaatctttgatgccatgcgcacattttcagccagtgatgaagtccagaaacttgga
tgtaaagttttacatgtgctgtttgagagagtttcagaggagcaactgactgaatttgtt
gaaaataaagattatatgatattgctaagtgcattaaaaaattttgaagatgaagaggaa
attgtgcttcatgtactgcactgtttacattccttagcaattccttgtagtaatgttgaa
gtcctcatgagtggcaatgtcaggtgttataatattgtggtagaagccatgaaagcattc
cctatcagtgaaaaaattcaagaagtgagttgctgcttgctccataggcttacattaggt
aatttctttaatatcttggtattaaatgaggtgcatgagtttgtggtgaaagcggtgcag
cagtattccgaaaatgcagtattacagatcgcagccctcagctgcttagcactcctcact
gagaccattttcttaaaccaagacttagaggaaaagaatgagaatcaggagaatgatgat
gatgaagaagaagataaattgttttggctggaagcctgttacaaagcattaacttggcat
aggaagaacaagcatgtgcaggaggctgcctgttgggccctgaataatctccttatgtat
caaaacagtttacatgagaagattggagatgaagatggccagttccctgctcacagggag
gtgatgctgtccatgctgatgcattcttcatcaaaagaagtcttccaggcatctgcaaat
gctttgtcaactctgttagaacaaaatgttaattttagaaagatcctgttgtcaaaagga
atatatctgaatgtattggagttaatgcagaagcatatgcattctcctgaagtggctgaa
agtggctgtaaaatgctaaatcatcttttcgaagaaagtagcacttccctggatacaatg
gcagctgtggtccccaaaataataacagtcatgaaaagtcatgagacgtcattatcagtg
cagctggaagcacttcgagctatgttacattttatagttccaggcatcccagaagaatac
agggaagatactgaatatcagcataagctaaatatgattgaaaagcagtgttttaggaat
gatattcacaaattggtcctggcagctttgaacaggttcattggaagtcctgggattcag
aagtgtggattaaaagtaatttcgtctataacacattttcctgatgcactagaggtgtta
tccctggaaggtgctattgattcggtgcttcatacactgcagatgtatccagatgaccaa
gaaattcagtgtctgggtttaagtcttataggatgtttgattacaaagaagaatttatgc
acggtaactgggtatctgctggcgaaaattctgatttccaccctacagcgatttaaggat
gttggtgaagtacagataaaaggatttcaaacagtcttgacaatactggaattgtcagtg
tctttttccaagctactggtgcatcactgctttgattcagtaatattccatcagttgtcc
tccagtatcatggagcaaaaggatcaacagtttctaaacctttgttgcaagtgctttgca
aaattgactattgataatgagttaaaatgtgtgttgctggagaaagcatgtgatcagaat
aatagcatcatggttgaatgcttgcttctgttgggagcggatgccaatcgagcaaaagaa
gcaacttctttgatatgtcaggtatgtgagaaagcaagcaatcccaaactggtagaattg
ttactgaatagtggatctcgtgagcaggatgtccggaaagctctgacaatcagcattggg
aaaggcaacagccaaatcatcagcttactcttgaggaggcttgccctggatctggccaat
aatagcatctgtcttggaggattttgtatgggaaaaattgaaccttcctggcttggtcct
ttatttccagataagacatcttatttaagaaaagagacaaatataggatccaccctggca
aggatggtgctcagatatcagatgagaagttctgtggaggaaggagctggctcaggaagc
aatgggaatttttctgaagaaatggttgataaatttgatgaatggaccttcattcctgag
tcttacattgacagtgtgtttggtcaaagtgatgacctggatagtgaaggaagtgaaggc
tcatttcttgtgaaaaagaaatcaaattcaattagcgtgggagagttttaccgagatcct
gccttgcaacgttgctcaccaaatttgcaaagacattccagttcattgggacccattttt
gatcatgaagatttactaaagagaaaaagaaaactattttcatcagatgattcactcaga
gcatcaaaattccagtcccatatgaggcattcagagagcatttcttccctgccttctgag
agagaatatattacatcgttagacctttcagcaaatgaactaagagatgttgatgccctg
agccagaactcctgtataagtggtcatttggaacatcttgaaaagctggagcttcaccag
aattcactcacaagctttccacaacagctgtgtgaaactctgaaatgtttaacacatttg
gatctgcatagtaataaatttacatcatttcccacttacttgttgaaaatgagttgtatt
gctaaccttgatgtctctcgaaatgatattggaccctcggtagttttggaccctgctgtg
acgtgcccgaccttgaaacagtttaacttgtcatataatcagatatcttctcttcctgcg
aaccttggtgacgtggtagagaaattggaacagctcattttagaaggaaataaaatatca
gaaatatgttcccctttgagcctgaaggaactgaagattttaaaccttagtaaaaaccac
atttcatctttatcagaggacttccttgagacttgtcctaaagtggagattttaagtgcc
agaatgaattttcttgctgctatgccttttttgccttcttctatcacaagcctaagatta
tctcaaaacagattcacatgtgtcccagaagcaattttacatctcccacatctgcggtcc
ttagatatgagcagcaatgatattcgatatctaccaggtcctgtgcactggagatctttg
aacttaagggaactcttgtttagtcataaccagatcagtatcttggacttgagtgaaaaa
gcatgtgcatggtctagaatagagaaactacatctttctcataataaactgaaagagatt
cctcctgagattggctgtcttgaaaatctgacatctcttgatgttagttacaacttggaa
ctgagatcctttcctaatgaaatggggaaattaagcaaaatatgggatcttcctttggat
gaactgcatcttaattttgattttaaacatgtaggatgtaaagccaaagacatcataagg
tttcttcagcagcggttgaaaaaggctgtgccctacaaccgaatgaaacttatgattgtg
ggaaatactgggagtggcaagaccaccttattgcagcaattgatgaaaatcaagaaatca
gatcttgggatgcaaggtgccacagttggcattgatgtgaaagactggcccatccaaata
agaggcaaagggaagaaagacctcattctgaatgtatgggattttgcaggtcgtgaggag
ttctacagcactcatccccactttatgacccaacgagccttgtatcttgcggtctatgac
ctcagcaaagggcaagctgaagttgatgccatgaagccttggcttttcaatataaaggcc
cgtgcttcttcttcccctgtgattcttgttggcacacatttagatgttactgatgagaag
cagcgcaaagcctgtatcagtaaaattaccaaggaactcttgaacaaacgagggtttcct
gcaatacgagattaccactttgtgaatgccactgaggaatccgatgctttggcaaaactt
cggaaaaccatcatcaatgagagccttaatttcaagatccgagatcagcctgttgttggg
cagctgattccagactgctacgtagaacttgagaaaatcattttatcagagcgtaaaaat
gtgccaattgaatttcctgtaattgaccggaaacgattattacaacttgtgagagaacat
cagctgcagttagatgaaaatgagcttcctcatgcagttcactttctaaatgaatcaggg
gtccttcttcattttcaagacccagcactgcagttaagtgacttatattttgtggaaccc
aagtggctttgtaaagtcatggcacagattttgacagtgaaagtggaaggctttccaaaa
catcctaagggaattatttcacgtagagatgtggaaaaatttctttcaaagaaaaagaga
tttccaaagaactacatggcacagtactttaaactcctagaaaaattccagatcgccttg
ccaattggagaagaatatttactggttccaagcagtttgtctgaccacaggcctgtaata
gagcttccccattgtgagaactctgaaattatcattcgactgtatgaaatgccttatttt
ccaatgggcttttggtcgagattaatcaatcggttgcttgaaatttcaccttacatgctt
tcaggaagagaacgagcacttcgtccaaacagaatgtattggcgacaaggcatctacttg
aattggtctcctgaagcttactgcttagtaggatctgaagttttagatcatcacgcagag
agtttcttaaaaattacagttccttcttgtagaaaaggctgtgttcttttgggccaagtt
gtggaccacattgattctctcatggaagagtggtttcctggattattggagattgatatt
tgtggtgaaggagaaactctgctgaagaaatgggcattatatagttttaatgatggtgaa
gagcatcaaaaaatattgcttgacaacttgatgaagaaagcagaagaaggagaccttcta
gtaaatccagatcaaccaaggctgacaattccaatatctcagattgctcctgacttgatt
ttggctgatctgcctagaaatattatgttgaataatgatgaattggaatttgaacaagct
ccagagtttctcttaggtgacggcagttttggatctgtttatcgagctgcgtacaaagga
gaagaagtggctgtgaagatttttaataaacatacatcacttaggctgttaagacaagag
ctggtggttctttgccatcttcaccatcccagcttaatatctttgctggcagctgggatt
cgtcctcgaatgttggtgatggaattagcctccaagggttccctggaccgcctgcttcag
caagacaaaaccagtcttaccagaacgctgcagcacagaatcgtgctacacgtggccgat
ggcctgagatacctccattcggccatgattatataccgtgacttgaagccccacaatgtt
ttgcttttcaccctgtatcccaatgctgccatcatcgccaagattgcggactatgggatt
gctcagtactgctgtagaatggggataaaaacatcagagggcactccaggttttcgtgca
cctgaagttgctagaggaaatgttatttataaccaacaagctgatgtttattcatttggt
ttgctactttatgacattttgacaactggaggtagaatagcagaaggtttgaagtttcca
aatgagtttgatgaattggcaatacaagggaaattacctgatccagttaaagaatatggt
tgtgccccatggcctatggttgagaagttaattaaaaaatgtttgaaagaaaatcctcaa
gaaagacctacttctgcccaggtctttgacattttgaattcagctgagttaatctgtctg
atgagacgtatatcaatccctaaaagctttactgttgaatgcatggttgctatgaatcat
aacagcaagaatgtgaggatttggctgggctgtgggcacacggacaaaggacagctctca
tgtcttgacttaaatacagaaagatacacttctgaggaagttactgatagtagaatattg
tgccttgccttggtgtatcttcctgttgaaaaggaaagttggattgtgtctggaacacag
tctggcatgctccttgttgttaatactgaagatgggagaaagaggcatacccttgaaaag
atgactgattctgttacttgcttgtattgcaattccttttccaagcaaagcaagcaaaaa
aatttccttttagtgggaactgctgatggcaacttagcaatttttgaagataaaactgtt
aagtgtaaaggagccactcctctgaagatactcaacataggaaatgtcagcactccactg
atgtgtttgagtgaatctgtgaacttaactgaaaaaaatattatgtggggaggatgtggt
acaaaagttttctcattttctgatgatttcaccattcagaaactcattgagaccaggaca
aatcagcgattttctaatacatctttctgtgattccaacatcatcgcagtggtggtagac
acggctctttatgttgctaagaaaaatagcccatgtgtggaagtgtgggataagaagact
gaaaaactctgtgaactgatagattgtgtgcactttttaaaggaggaactggtcagagta
agcaaggaatcgaaacacaaaatgtcttattctgggagagtgaagactctctgccttcag
aagaacactgctctctggataggaactggaggaggccatatcttactccttgatctttca
actcgtcgaattatacgtataattcacaacttttgtgattctgttagagtcatgatgacc
gcacagttaggaagccttaaaaatgtcatgctggttttgggttataaccggaaaagtgct
gaaggtacgcaacaccaaaaagagatacagtcttgcttgtctgtttgggacatcaatctt
ccacatgaagtgcaaaatttagaaaaacatattgaagtgagaaaagaattagctgaaaaa
atgagaagaatatctgttgaataa
DBGET
integrated database retrieval system
