Odocoileus virginianus (white-tailed deer): 110145571
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Entry
110145571 CDS
T10722
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
ovr Odocoileus virginianus (white-tailed deer)
Pathway
ovr00310
Lysine degradation
ovr01100
Metabolic pathways
ovr05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
ovr00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
110145571 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
110145571 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ovr03036
]
110145571 (DOT1L)
Enzymes [BR:
ovr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
110145571 (DOT1L)
Chromosome and associated proteins [BR:
ovr03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
110145571 (DOT1L)
HMT complexes
Dot1-containing complex
110145571 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
110145571
NCBI-ProteinID:
XP_020761616
UniProt:
A0A6J0YKW9
LinkDB
All DBs
Position
3:19013010..19064583
Genome browser
AA seq
1714 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVVFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTPVDSGAEEEKAGTAAVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSAT
NPERKPKKTQSALDLLHAQTVSRAASPLPQDAHRPPHSPFYQLPPSVQRPTPEQLLLAPT
PPALHRLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQTEQLEKGNRELRSQSLRLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDEALTLQLRGKPEAEPGRLHLELDCARFSLPPFSSLSPELSMNGHAAGYELCSAL
GRPSPKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKLVLRRHLS
QDHGASGKAAASELHPRAEHAKENGLPYQSPGITNGIKLSPQDPRPSSPMALQMGEKGPE
KGVKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKARSTPSPGPPA
RESSSTLEKQVAANTHGTGGNASGSKSLALAPTGFAYTGSVAISGALAGSPAPLGPGAEP
PALDESSSSGSLFATVGSRSSTPQHPPLLTQPRACGSASPAPQLSASPRLGALGPLPDSG
KGDLPCEASFSDPESEAKRRIVFTISAGASSAKQSPSSKHSPLPSGARGDGGQGHGPDSR
KRGRRKRASAGTPSLSSSVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAIS
SPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEPGSARIERKI
ATISLESKSPPKTLENAGGSLTGRKAPLASEPVNSSKWKSTFSPISDLGLAKAADSPLQA
ASALSHNSLFAFRPSLEEPSAADAKLATHSRKSFPGTLPGAGGLSPSSLPASGFALGGGL
ATDLSLHSFSDGASLSHKAPEAAGLGAPLSFPGPRGKEGGAAESGPFANKRQLDGLGPKG
EGGLPTCGPPDKASAVHSKAGKGREREPDVKNGHNLFMAAVAAPPAGLLSGPGLAPAASS
AGGAAPSVQTHRPFLGTFTPGPQFALGPMSLQANLGPSVLQSLFSSVPAAGLVHVSTAAT
RLTNSHAMGSFSSGVAGGAVGGVFNHAVPPASAHPFGASFGSGAACRSTTLSLTPPQAVA
SIPASSFQAPSSAEPRPPPPPPHLGRPPPGQPALHSPPHPNATLPSPPVLLPANSEPVLL
QNLASLPANQAFLPASSAASLPPANASLSIKLASLPHKVSRPSLTVHHQPLPGLALAQAT
PANPQASSTGPPAVWVSLGMPPPCAARLAGVKPR
NT seq
5145 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctac
ccatggccgctgccggtctacgacaaacaccatgatgctgctcatgaaatcatcgagacc
atcagatgggtctgtgaagaaatcccggatctcaagcttgctatggagaattacgtttta
attgactacgataccaaaagctttgagagtatgcagaggctctgtgacaagtacaaccgg
gccatcgacagcatccaccagctgtggaagggcaccacacagcccatgaagctgaacaca
cggccgtccacggggctcctgcggcacatcctgcagcaggtctacaaccactcagtgacc
gaccctgagaagctcaacaactatgagcccttctccccagaggtgtatggggagacctcc
ttcgacctggtcgcccagatgatcgatgagatcaagatgaccgaagatgacctgttcgtg
gacctgggcagtggggtgggccaggtcgtgctgcaggttgctgcggccaccaactgcaaa
catcactatggtgtagagaaagctgacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggagagg
ggggacttcctctcggaggagtggagagaacggattgctaacacaagtgttgtatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcggtttgcaaacatg
aaggaaggtggcagaatcgtgtcctcgaagccctttgcgcctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctgtcgccgctaaaa
ggctcggtgtcgtggacggggaagccagtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctaaaaaatccaaaactcagggaggaacaagaggca
gctcggcgccggcagcagcgggagaacaagagcaacacaaccacacccaccaaggtgccc
gagagcaaggcagctgtgcccgcggacacccccgtggactctggtgctgaggaggagaaa
gctgggacggccgctgtcaagaagccatctccctccaaggcccggaagaagaagctgaac
aagaagggccggaagatggcaggtcggaagcgcgggcgccccaagaagatgagtgccacc
aaccccgagcgcaagcccaagaagacccagagcgcactggacctgctgcacgcccagact
gtgtcacgagcggcctcccccttgccgcaggatgcgcacaggccacctcacagcccattc
taccagctacctcccagtgtgcagcggcctacccccgagcagctgctgctggcacccacc
ccgcccgccctgcacaggctgctagagtccttcaagattcagtacctacagttcctggca
tacacgaagacccctcagtacaaggccaacctgcagcagctgctggaccaggagaaggag
aagaatgcccggttgctaggcgcagcgcagcagctgttcggccactgccaagctcagaag
gaggagatcaagaggctcttccagcagaaactggacgagctgggagtgaaggcgctgacc
tacaacgacctgatccaagcgcagaaggagatctcggctcacaaccagcaattgagggaa
cagacagagcagctggagaagggcaaccgggagctgaggagccagagcctgagactgctc
aaggcacggtgtgaggagctgaagctggactggtccacgctgtccttggagaatctgctg
aaggagaagcaggccctgaagagccagatctcagagaagcagaggcactgcctggagctg
cagatcagcattgtggagctggagaagagccaacggcagcaagagttgctgcagctcaag
tcctgcgtgccgcctgacgaggcgctgaccctgcagcttcgtggaaagccagaggccgag
cctggccggctgcacttagagctggactgcgcccgcttctccctgccacccttcagcagc
ttgagccccgagctctccatgaatggccacgcggccggctatgagctctgcagcgcactg
ggtcggccctcgcccaagcagaacaccccccagtacctggcctccccgctagaccaggag
gtcgtgccctgcacccccagccacagtggccggccacggctggagaagctgtctgggctg
gccctgcctgactacaccaggctatcccctgccaagctggtgctgcggcgccatctgagc
caggaccacggggccagcggcaaggcagctgccagtgagctgcacccacgagccgagcat
gccaaggagaacgggctcccttaccagagccctggcatcaccaatggcatcaagctgagc
ccacaagacccccgaccttcatcccccatggctttacagatgggagagaagggtcctgag
aagggtgtgaaggagcgtgcctacgccagcagtggggaggccatcaccagcctgcccgtc
agcatcccgctgagcaccgtgcagcccagcaagctgcccgtcagcatccccctggccagc
gtggtgctgcccagccgcgccgagaaggcgagaagcacacccagccctgggccgccggcc
cgagagtcgtcatccacgctggagaagcaggtggctgctaacacccatggtaccgggggc
aacgcttccgggagcaagagcctcgccctggctcccacaggctttgcatacaccggctcg
gtggccatcagtggggccctggcgggcagcccggcacccctcggccctggagccgagccc
ccagccctggacgagtcctccagctctggaagcctctttgccaccgtggggtcccgcagc
tccaccccgcagcacccgcccctgctgacgcagccacgtgcctgcggctcggcctcgccg
gccccgcagctctctgccagcccccggctaggcgccctgggcccgctccctgactctggc
aaaggggacctgccctgcgaggccagcttctcagaccctgagagcgaagccaagaggagg
atcgtcttcaccatctctgcaggcgccagcagcgccaagcagtcaccttccagcaaacat
agccctctgccttcgggtgcccgtggggacggtggccagggccatgggccagacagccgc
aagcggggccggaggaagcgggcgtcagcggggacccccagcctgagctcgagtgtgtcc
cccaagcgccgggccttgccatctgttgctgggcttttcacgcagtcttcagggtccccc
ctgaacctcaactccatggtcagcaacatcaaccagcccctggagatcacagccatctcg
tcccctgagagctccctaaagagctcacccgtcccctaccaggacaacgaccaaccaccc
gtgctcaagaaggagaagcccctgagccagaccaatggcgcccactactccccgctgacc
tcggacgaggagccaggctctgaggatgagcctggcagtgccagaattgaaagaaaaatt
gcaacaatctccttagaaagcaagtctccaccaaaaaccttggaaaatgcaggtggcagc
ctaacgggaaggaaggcaccgctggccagtgagccggtcaacagcagcaagtggaaatct
accttctcgcccatctccgacctgggcctggccaaggcagccgacagcccgctgcaggct
gcttccgctctgagccacaactccctgttcgctttccggcccagcctggaggagcccagc
gcggccgatgccaagctggccacccactccaggaagagcttcccgggcacactgccgggg
gcgggcgggctgagccccagtagccttcctgccagcggcttcgccctgggcgggggccta
gcaactgacctcagtttacacagcttcagtgatggtgcttctctctcccacaaggccccc
gaggcagctggcctgggtgcccccctgagcttccccggcccacggggcaaggagggtggc
gccgcagagtctggcccctttgcgaacaagcggcagctggacggactgggcccgaaaggc
gaggggggccttcccacatgcggacccccagacaaggcctcagcagtgcatagcaaggcc
ggcaagggtcgtgagcgcgagcccgacgtcaagaatggccacaacctgttcatggccgcc
gtcgccgcaccccctgcaggcctcctcagtggcccaggtcttgccccagcggcatcctcg
gcaggtggcgcagccccgtccgtgcagacccaccgccccttcctgggcacctttaccccc
gggccacagttcgcgctgggccccatgtcgctacaggccaacctgggcccgtctgtgctg
cagtccctgttcagctccgtgcccgccgctggcctggttcacgtctcgaccgccgccacc
agactgaccaactcgcacgccatgggcagcttctcctctggggtggccggcggcgcagtt
ggaggtgtctttaaccacgcggtgcctcccgcctccgcccatccgtttggagccagtttc
ggcagtggggctgcatgtcgcagcaccacgctgagcttaaccccgccgcaggcggtggcc
agcatcccggcctcttcctttcaggccccgtcctctgcggagccgaggccgcccccaccc
cctccgcacctgggccggccccctccggggcagcccgccctccattcacccccccatcct
aatgccaccttgccttctccccctgtgctgctcccagctaactctgagcccgtgcttctg
cagaacctcgcatccctccctgctaaccaagctttcttacccgcctcctctgctgcctct
ctgccgcctgctaacgcctctctgtccatcaagctcgcctccctcccgcacaaggtgtcc
cgcccttccttgacggtgcaccaccagcccttgcctgggctggccctggcccaggccaca
cccgcgaacccacaggccagctccacggggccgcccgccgtgtgggtttcccttggcatg
ccgcctccgtgtgccgcgcgccttgcgggggttaagccgcgataa
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