Pyrococcus abyssi: PAB0287
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Entry
PAB0287 CDS
T00024
Symbol
leuC-2
Name
(GenBank) leuC-2 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
pab
Pyrococcus abyssi
Pathway
pab00290
Valine, leucine and isoleucine biosynthesis
pab00660
C5-Branched dibasic acid metabolism
pab01100
Metabolic pathways
pab01110
Biosynthesis of secondary metabolites
pab01210
2-Oxocarboxylic acid metabolism
pab01230
Biosynthesis of amino acids
Module
pab_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
PAB0287 (leuC-2)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PAB0287 (leuC-2)
Enzymes [BR:
pab01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
PAB0287 (leuC-2)
4.2.1.35 (R)-2-methylmalate dehydratase
PAB0287 (leuC-2)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
CAB49359
UniProt:
Q9V1J0
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All DBs
Position
420738..421880
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AA seq
380 aa
AA seq
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MTLVGKLLNAKPGEAVIRKVDLVYAHDGTMPLIIEAFNRIFNEVRTRAYIFFDHVYPAPT
VKVANLHREIREFAKIHGIPVVEGKGISHQLVVELGLAEEAKIIVGGDSHTPTLGALGVF
AVGMGATDVAIALGLGKIWLKVPESIAVLLDGSPREYIMASDVMIHLITSLKDREMSYNA
IEFFNVPFSFDERLTLTNFSVEANAKTAIIGEEYEGGGYSDEITIELDSLPPMVAKPFSP
ANGVSVEDVEGTKIDQVFIGSCTNGRFEQIKRAAEILDGEQVNVRTLVAPASINVYRRMI
EEGLVRILIDAGVVILPPGCGPCLGRHMGVAGDNEVILSTTNRNFRGRMGSPKAEIYLAS
PVTAAVSALYGEITNPEGEL
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgacccttgttggaaaactacttaacgctaagcccggtgaggctgtaataaggaaagtc
gacctagtttacgcgcacgatggaacgatgcctctaataatagaggccttcaataggata
ttcaatgaggttagaactagggcttacatattctttgaccacgtttatccggcacctacg
gtaaaggttgcgaacctgcatagggagataagggagttcgccaagatccatggtattcca
gttgttgagggaaagggaataagccatcagctcgtcgttgagcttgggcttgcagaggag
gcaaagataatcgttggtggtgattctcacaccccaacgcttggagctcttggtgtgttc
gctgtaggtatgggtgctacggatgttgccatagctctagggcttggaaagatatggctt
aaggttcccgagagcatagcagttttactggatggttccccaagagaatacataatggct
tccgacgttatgatacacctaataacatcccttaaggatagggagatgagctacaatgcg
atagaattctttaacgttccgttctccttcgatgaaaggttgacgctcactaacttcagc
gttgaagcaaatgcaaagacggcaataatcggagaggagtacgagggagggggatactca
gatgagattaccattgagttagactctttacctccaatggttgcgaaaccttttagtcct
gctaacggcgtgagcgttgaggatgtagagggaactaagatagaccaagttttcataggt
tcatgcactaacggtagattcgaacaaataaagagagcggctgagatattggatggggag
caggttaatgttagaaccctggttgctccagcctccatcaacgtctatagaaggatgatt
gaggaaggattagttaggattctgatagacgctggtgttgtaattctaccgcctgggtgt
ggaccgtgtcttggaaggcatatgggagttgctggagacaatgaggttatcctctcaact
acgaacaggaatttcaggggaaggatgggttctccaaaggctgaaatttaccttgcgagt
cctgttactgccgcggttagcgctctttacggtgagataacgaacccggagggagagtta
tga
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