Pyrococcus abyssi: PAB0890
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Entry
PAB0890 CDS
T00024
Symbol
leuA-1
Name
(GenBank) leuA-1 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
pab
Pyrococcus abyssi
Pathway
pab00290
Valine, leucine and isoleucine biosynthesis
pab00620
Pyruvate metabolism
pab01100
Metabolic pathways
pab01110
Biosynthesis of secondary metabolites
pab01210
2-Oxocarboxylic acid metabolism
pab01230
Biosynthesis of amino acids
Module
pab_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
pab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
PAB0890 (leuA-1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
PAB0890 (leuA-1)
Enzymes [BR:
pab01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
PAB0890 (leuA-1)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
URO-D
YjeJ
PTE
tRNA_bind_2
F420_ligase
Motif
Other DBs
NCBI-ProteinID:
CAB50254
UniProt:
Q9UZ08
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All DBs
Position
1305441..1306901
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AA seq
486 aa
AA seq
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MRKVYIFDTTLRDGEQTPGVSLTVEEKVEIAKQLAKLNVDVIEAGFPIASEGEFKAVKKI
ATEVEDPTIAALARAVEKDIDRAGEALRNAEKNRIHTFIATSPIHMKYKLRKEPEEVKKL
AVKAVEHATKYTEDVEFSAEDATRSDWDFLVEVYEAVIDAGATVINVPDTVGYATPEEFY
ELVRYLRRNISNIKGVQISVHCHDDLGLAVANSLSAIRAGADQVEVTVNGIGERAGNAAL
EEVIVALDVRRDFYKVKTDVNLKEIARTSKLVSHLTGIEVPPNKAIVGGNAFAHESGIHQ
DGVLKERTTYEIIDPKKLGFSGSKIVLGKHSGRHAFRKKLEELGYSLTEEHLERAFKKFK
DIADRKRWITDTDIEAIIQEELTKSNGKLKVEIIHVTSGKVSTATVRISMNGEERIEVAW
FKNGPIDALFSAINKALGEEFKLREYRVSSVTSGKDSLGEVLVRVEVNGEIFVGRGLSTD
IIEASA
NT seq
1461 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaagtttacatctttgacacaacactaagggatggggagcaaactccgggagtt
agtttaaccgttgaagaaaaggttgagatagctaaacagctagctaagctcaacgtggat
gttatagaggctggatttccaatagcgtctgagggagagttcaaggctgtaaagaaaata
gcaacagaggtggaagatccaacaatagcagccctagctagagctgtggagaaggatata
gacagggctggggaggctctaaggaatgcagaaaagaataggatacatacattcatagcc
acctcaccgatacacatgaaatataaactcagaaaggaacctgaggaagttaaaaagcta
gctgttaaagcggtagaacacgcaaccaagtatactgaggatgtagaattctcggccgaa
gatgcaacgagaagcgactgggatttcctagttgaggtttatgaggctgttatagacgct
ggagctaccgtgataaacgttcccgacaccgtaggttacgctacccctgaagagttttac
gagttagtgagatatctaaggaggaacattagtaacatcaagggggttcaaataagcgtt
cactgtcacgatgacctcggcttagcagttgcaaactccctttcagcgattagagctgga
gcggatcaagttgaagtaacggttaacggaataggggagagagctggaaacgctgctcta
gaggaggttatcgtagctcttgacgttaggagggatttctacaaggttaaaacggatgta
aacttaaaagagatagccaggacaagtaagttagtttctcacttaaccggaatagaagtc
ccaccaaacaaggcgattgttggagggaatgcttttgcgcacgaatccggaattcatcag
gatggtgtgctcaaagaaagaacgacttatgaaataatagaccctaagaaactaggattc
tccgggagtaagatagtgcttggaaagcactctggaaggcatgcatttaggaagaagctt
gaagaactaggttacagcttaacagaagagcaccttgagagggctttcaagaagttcaag
gatatcgccgataggaagaggtggataactgacacagacatagaggctataatccaggag
gagcttacgaaatcgaatggaaagctcaaggttgagataatacacgtaacttcagggaaa
gtatcaaccgctacagtcaggattagtatgaacggagaggaaagaatagaggttgcttgg
tttaagaatggaccaatagatgctctattctcggcaatcaataaagcccttggagaggaa
ttcaagcttagggagtacagggtatcttctgtaacatctggtaaagattctcttggagaa
gttctagttagagttgaagtaaatggggaaattttcgttggtaggggattaagtaccgat
attatcgaggctagcgcttag
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