Cutibacterium acnes HL096PA1: PAGK_1374
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Entry
PAGK_1374 CDS
T02638
Name
(GenBank) UDP-N-acetylmuramyl pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pach
Cutibacterium acnes HL096PA1
Pathway
pach00300
Lysine biosynthesis
pach00550
Peptidoglycan biosynthesis
pach01100
Metabolic pathways
pach01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pach00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PAGK_1374
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PAGK_1374
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PAGK_1374
Enzymes [BR:
pach01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PAGK_1374
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
AGJ80200
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Position
complement(1531911..1533368)
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AA seq
485 aa
AA seq
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MRVLDVATLAQWVEAAPVNDSAQVGPDVVIDTRKVTPGALFIALPGTRVDGHDFTQAAQD
TGAAAVLVTRRTDAQLPHLVVDDGQAGLSRLARHVVATERERGMRTIALTGSSGKTSTKD
MLAQILETFGPTVAPVGSFNNEIGVPLTACRSNENTSFLVSEMGTRGLGHISWLTSIVTP
DVAMVLNVGNAHLGEFGSREVIAQAKGEIVEALSVDGWAVLNAADTLVAGMAPRTRGHIA
WFSPDADHRRPDADIEVWAESTHADDLDRHSFTLAARRGESTWRSPVRLMTMGAHQVANA
VAATAAALAALAMNDDIDDQTVTRIAEALSNAVSRSAMRMQLRERADGLVLVEDCYNANP
DSMAASLTSMGHVLATRRVRDPQTRGVAVLGDMLELGQDSARLNAESGRLAAHAGFDVII
AVGDEAENIAEGARAEGARVIVSTVEGASGSLGWTSHDVVLLKASRGLALERVGREVFEE
REAQA
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atgagagttctcgacgttgccaccctcgcgcagtgggtcgaagcagcaccggtaaatgat
tctgcccaggtgggcccggacgtcgtcattgatacccggaaggtaactccgggcgctctg
tttatcgctcttcccggcacccgggtagacggtcatgacttcactcaggcggctcaggac
acgggcgctgccgctgtcctggtcactcggcgcaccgacgcacagttgccccatctcgtt
gttgacgatggtcaagccggcctatctcgactggcgcgtcatgtcgtggcgactgaacga
gaacgtggcatgcgtaccatcgctttgactggttccagcggtaagacaagcaccaaggac
atgctggcccagatccttgagacttttggcccaacggtggctccggtgggatcgttcaac
aatgaaatcggagttcctctgacggcgtgccgcagtaacgagaacacctctttcttggtg
tcggaaatggggactcgcggtctgggtcatatctcctggctcacctccatcgttactccc
gacgtagccatggtcctcaacgtcgggaatgcccacctgggcgagtttggttcgcgagag
gtcattgcccaggctaagggtgagatcgttgaggccctcagcgttgacggttgggctgtg
ctcaacgccgccgatacccttgtcgccgggatggcaccgcgcacccgtggacatattgca
tggttcagccctgatgctgaccatcgtcgcccagatgccgacatcgaggtgtgggccgaa
tcaacccatgccgacgacctggatcgtcactcctttacccttgccgcccgccggggtgag
tccacctggcgtagccctgtccggctgatgacgatgggtgctcatcaggtcgcaaatgcc
gtggctgctactgctgctgcgctggcagccttggctatgaatgacgacatcgatgaccaa
actgtcactcggatcgccgaggcgctcagcaacgccgtgtccaggtcagctatgagaatg
cagttgcgtgaacgcgccgatggcctggtgctggtcgaggactgctacaacgccaaccct
gactcgatggccgcttcgttgacatcgatggggcatgtcttggcgacgcgccgagttcgg
gaccctcagactaggggcgtcgccgtcttgggcgacatgctcgagcttggacaggactct
gctcgtctcaatgccgagtccggtcggctagcagcccacgctggattcgacgtcattatc
gctgttggcgatgaggccgagaacattgccgaaggtgcccgggccgaaggcgcacgtgtg
attgtttccaccgtggaaggtgcttctgggtcactaggttggacctcacacgatgtcgtt
ttactcaaagcttccagaggtctggccttggagcgagtaggacgcgaagtgttcgaggaa
agggaggcccaggcgtga
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