Pediococcus acidilactici: A4V11_05230
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Entry
A4V11_05230 CDS
T04512
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
paci
Pediococcus acidilactici
Pathway
paci00300
Lysine biosynthesis
paci00550
Peptidoglycan biosynthesis
paci01100
Metabolic pathways
paci01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
paci00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
A4V11_05230
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
A4V11_05230
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
A4V11_05230
Enzymes [BR:
paci01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
A4V11_05230
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MurT_C
LpxD
Motif
Other DBs
NCBI-ProteinID:
AOW74440
UniProt:
A0AAN6BEQ6
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All DBs
Position
complement(1056491..1057870)
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AA seq
459 aa
AA seq
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MKMQLSEIARALGVDEYPDQWNEVSVTSVQFDSRQLTPGSLFVPIKGQRDGHQFIEQAIQ
AGAVATLWAKDHEDTRPADLPSIEVEDPLAALQKLAKYYLDKINPKVVAITGSNGKTTTK
DMTAAILATEFNVVKTEANFNNEIGVPITILGMNANTEVLVVELGMDRPGQLHFLSELVQ
PDIAVITMIGEAHIEFFKTRDRIADAKMEITDGLKEDGCFIYDGDEPLLAERAKAVDVEQ
RTFGMKNENDVFASDVAGTDTETSFKTNLDPEVEVKLPIIGEYNVKNALAAITVGDRYHV
GVADSARALADFNLTKNRTEWLKGRQGERILSDVYNSNPTAAKAVLNSFAHTKKTGRRFV
VLGDMLELGENADQMHAQLADSLNPAQFEEVFLVGQHMRALGKRLVDEEIYPAEAVHLYD
ANELPQLTTDLQQMIKADDCVLLKASHGIHLEKVVEQLK
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcaactaagtgaaattgcccgtgctctaggagtagacgagtatccggaccaa
tggaatgaggttagtgtcaccagtgtccagtttgatagtcgtcaattaacgccgggttct
ttgtttgttccaatcaagggacaacgcgacggtcaccaatttattgagcaggctattcag
gctggcgcggttgcaacgttatgggcgaaggatcatgaagatacccgcccggcagatttg
ccaagtattgaagtggaagatccgctggctgcgttgcaaaaattagcgaaatactactta
gataaaatcaatcccaaagttgtggcaattacgggaagtaacggaaaaactacgacgaag
gacatgactgccgccattttggcgaccgaatttaacgtggtgaagacggaagccaacttc
aataacgaaattggggttccaatcaccattttgggaatgaacgcaaatactgaggttcta
gtggttgaattagggatggaccgccccggacagttacatttcttaagtgaattagtccaa
ccggacatcgcggtaattaccatgattggcgaagcccacattgaattctttaagacgcga
gaccggattgcggatgccaaaatggaaattacggacggtttaaaggaagacggttgcttt
atttacgatggtgacgaaccgttactagcggagcgggccaaggcggtggatgttgaacaa
cgtacgtttgggatgaaaaatgaaaacgacgtattcgcatccgatgtagcaggtaccgat
actgaaacatcatttaagactaatttggaccccgaagtggaggttaaattaccaattatt
ggcgaatataacgtaaaaaatgcgttggcagccattacggtaggtgatcgataccacgtc
ggagttgcggacagtgctcgtgcattggcagattttaacttaaccaagaaccggaccgaa
tggctaaaaggccggcagggagaacgaattttaagtgacgtatataattctaatcctacg
gcagctaaagcagtgttaaactcctttgcacatactaagaagaccgggcgccggtttgtg
gttctgggagatatgttagaactgggagaaaatgccgaccaaatgcatgcccaattagcg
gacagtttaaatccggctcaattcgaagaagtatttctcgtgggccagcatatgcgtgcg
ttaggaaaacggctggttgacgaagaaatttatccagcagaagccgttcatttatacgac
gcaaacgaacttccgcaattaactactgatttacaacaaatgattaaagctgatgactgt
gtactattaaaggccagccacgggattcatttggaaaaagtggttgaacagcttaaataa
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