Arcobacter acticola: AACT_0721
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Entry
AACT_0721 CDS
T06605
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
paco
Arcobacter acticola
Pathway
paco00290
Valine, leucine and isoleucine biosynthesis
paco00620
Pyruvate metabolism
paco01100
Metabolic pathways
paco01110
Biosynthesis of secondary metabolites
paco01210
2-Oxocarboxylic acid metabolism
paco01230
Biosynthesis of amino acids
Module
paco_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
paco00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AACT_0721 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AACT_0721 (leuA)
Enzymes [BR:
paco01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AACT_0721 (leuA)
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Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
IPMS_D2
NADH_4Fe-4S
Motif
Other DBs
NCBI-ProteinID:
QKE27923
UniProt:
A0A6M8E9J8
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All DBs
Position
704115..705668
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AA seq
517 aa
AA seq
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MDKNKIIVFDTTLRDGEQSPGCSMNTEEKIKIALQLEKLGVDVIEAGFAAASPGDFDAVS
RIAEMVKNSSICSLSRAIDNDIKQSGLAVSKAPKHRIHTFIATSPIHMKYKLKMSPDEVI
KRAIHAVEYARTFVDDVEFSLEDAGRSEIPFMKEVMDAVINAGARTINLPDTVGYRLPNE
LGAMVKELSAYAGDRAIISVHNHNDLGLATANTLAAVLNGARQIEVTINGLGERAGNSAL
EEAVMAIKTRKDAFGDLYTTINTPEIYATSRLVATVTGVEPQQNKSIVGKNAFSHESGIH
QDGVLKHQETYEIMKPEDVGVFKESTLILGKHSGRAAFRDKIVHMGFDKVSDEELNAAFE
RFKVLADKKKDVTDDDIRMLITDESLNQDKTYELVGLQISDCTAGVPTAAVAIKFKDQIM
KDAAIGDGTMDAIFKTIDRLTGYNGELKDYKVTSVTEGKDALAKVTTRVSFDETSPAFVG
HGLSIDTMLATAKAYLGALNSYLSQKERLSKNSEHQI
NT seq
1554 nt
NT seq
+upstream
nt +downstream
nt
atggataaaaataaaattatagtatttgatacaacattaagagatggtgagcaaagccct
ggctgttcaatgaacactgaagaaaaaataaaaattgcattacaattagaaaaattaggt
gttgatgtaattgaagctggatttgcagcagctagtcctggtgattttgatgcggttagc
cgaattgctgaaatggttaaaaactcaagcatttgttctttaagtagagcaattgataac
gatattaaacaatcaggtttagcagtatcaaaagcacccaaacacagaatccatacattt
attgcaacatcgccaattcatatgaaatataaattaaaaatgtcgccagatgaagtaatt
aaaagagcaattcatgcggttgaatatgcaagaacatttgtggatgatgttgagttttca
ttggaagatgcaggaagatctgaaattccatttatgaaagaagttatggatgcagttata
aatgcaggtgcaagaactattaacttaccagatactgtaggatatagattaccaaatgaa
ttaggtgcaatggttaaagaattaagtgcatatgcaggagatcgtgcaattatttctgtt
cataatcataatgatttaggattagcaacagctaatactttagctgctgttttaaatggc
gctagacaaattgaagttacaatcaatggattaggggagagagctggaaattcagcttta
gaagaggctgttatggctattaaaactcgaaaagatgcatttggagatttatatacaact
attaatactcctgaaatttatgcaacttcaagattagttgcaactgtaactggtgttgaa
ccacaacaaaataaatcaattgttggtaaaaatgcattctctcacgaaagtggaattcac
caagatggtgttttaaaacatcaagaaacatatgaaatcatgaaacctgaagatgtaggt
gtatttaaagaatcaactttaattttaggaaaacactcaggtcgtgcagcatttagagat
aaaattgttcatatgggatttgataaagttagtgatgaagaattaaatgctgcttttgaa
agatttaaagttttagctgataagaaaaaagatgtaactgatgatgatatcagaatgtta
ataactgatgagtcattaaatcaagataaaacttatgaattagttggattacaaatatct
gattgtacagctggagttccaacagcagcagttgctattaaattcaaagatcaaattatg
aaagatgcagctattggtgatggaacgatggatgcaatttttaaaactatagatagatta
acgggttataatggagagttaaaagattataaagtaacttctgtaacagaaggtaaagat
gccttagcaaaagttactacaagagtttcttttgatgaaacaagtccagcatttgtagga
catggattaagtatcgatacaatgcttgcaactgcaaaagcatatttaggtgcattaaac
tcatacctttctcaaaaagaaagattatctaaaaatagtgaacaccaaatttag
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