Paraburkholderia sp. DD10: ACOCG7_24615
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Entry
ACOCG7_24615 CDS
T11777
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
padd Paraburkholderia sp. DD10
Pathway
padd00290
Valine, leucine and isoleucine biosynthesis
padd00620
Pyruvate metabolism
padd01100
Metabolic pathways
padd01110
Biosynthesis of secondary metabolites
padd01210
2-Oxocarboxylic acid metabolism
padd01230
Biosynthesis of amino acids
Module
padd_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
padd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ACOCG7_24615 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ACOCG7_24615 (leuA)
Enzymes [BR:
padd01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ACOCG7_24615 (leuA)
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Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
XQP51169
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Position
1:2093303..2095018
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AA seq
571 aa
AA seq
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MLKNPASKYHAFKPIDLTDRQWPSRSITRAPIWMSTDLRDGNQALFEPMNAERKMRMFKT
LVQIGFKEIEVAFPSASQTDFNFVRELIEGGHIPDDVTIEVLTQARDDLIERTFESLRGA
PRAIVHLYNATAPEFRRIVFGLDQSGVKELAQNAARTMKRLADAAPETHFTLQYSPEVFS
GTELEFAKEVCDAVFEIWQPTPEHKAIVNLPATVEMSTPNVYADQIEWMHRNLARRDALI
VSVHPHNDRGTAVAAAELAVMAGADRIEGCLFGNGERTGNVDLVTLALNLYTQGVDPGLD
FSNINEVARTAEECTQLPVHPRHPYVGDLVFTAFSGSHQDAIKKGLAVQKPDAVWEVPYM
PIDPSDLGRTYDSVIRVNSQSGKGGIAYLLEQGYGVVLPRRLQVDFSSAVQRFSDDSGQE
VTPSQIWALFQQEYVESHAPVRYIGHSLSEQGNGARITLTVDVNGQRRVLNGAGNGPLDA
LMHAMGVPVRIQHYEERALTQGADARAIAIAEMAGNDIAGSAFGVGIDANLVTASIRAVI
SGVNRAYARANGAAQAQFFEAAMNDETATAD
NT seq
1716 nt
NT seq
+upstream
nt +downstream
nt
atgttgaaaaaccccgctagcaaataccacgcgttcaagccgatcgatttgacggaccgt
cagtggccgtcgcgcagcatcacgcgtgcgccgatctggatgagcaccgacctgcgcgac
ggcaatcaggccttgttcgagccgatgaacgccgagcgcaagatgcgcatgttcaagacg
ttagtacagatcggcttcaaggaaatcgaagtcgcgtttccgtccgcgtcgcaaaccgat
ttcaatttcgtgcgcgagctgatcgaaggcggccacattcccgacgacgtcaccattgaa
gtgttgacgcaagcccgcgacgatctcatcgagcgcaccttcgaatccttgcgcggcgcg
ccgcgcgcgatcgtccatctgtacaacgccacggcgccggaattccgccgcatcgtattc
ggcctcgaccagagcggcgtgaaggaactcgcgcaaaacgccgcgcgcacgatgaagcgt
ctcgccgacgccgcgccggaaacgcacttcacgctgcaatacagcccggaagtgttcagc
ggcaccgaactcgaattcgcgaaggaagtatgcgacgccgtgttcgagatctggcaaccg
acgccggaacacaaggcgatcgtcaatctccccgccaccgtcgaaatgtcgacgccgaac
gtctacgccgatcagatcgagtggatgcatcgcaatctcgcgcgccgcgatgcgttgatc
gtatcggtgcatccgcacaacgaccgcggcaccgcggtggcggccgccgaactcgccgtc
atggcgggcgcggatcgaatcgaaggctgcttgttcggcaacggcgaacgcaccggcaac
gtcgacctcgtcacgctcgcgttgaatctgtacacgcaaggcgtcgatccgggactcgac
ttctcgaacatcaacgaagtcgcgcgcacggccgaggaatgcacgcagttgccggtgcat
ccgcggcatccgtatgtcggcgatctggtgttcaccgctttctcgggctcgcatcaggac
gcgatcaagaagggccttgccgtgcagaaaccggacgcggtctgggaagtgccctatatg
ccgatcgatccgagcgatctcggccgcacttacgattcggtgattcgagtcaatagccag
tcgggcaagggcggcattgcgtacctgctcgaacagggttacggcgtggtgttgccgcgc
cgcttgcaggtggatttcagctcggcggtgcagcggttttccgacgacagcgggcaagaa
gtcacgccttcgcaaatctgggccctgttccagcaggagtacgtcgagagccatgcgccc
gtgcgctatatcggacatagcctgtccgaacagggcaatggcgcgcgaatcacgctgacc
gtcgacgtgaacggccagcggcgcgtactgaacggcgcgggcaacggtcccctcgacgca
ttgatgcacgcgatgggcgtgccggtgcgaatccagcattacgaagagcgcgcgctgacc
caaggcgccgacgccagggcgattgcgattgccgaaatggccggcaacgacattgcgggc
agcgcgttcggcgtcggcatcgacgcgaatctggtgaccgcgtccattcgagccgtgatc
agcggtgtgaatcgtgcctacgcgcgagcgaacggcgccgcgcaagcgcagttctttgaa
gccgcgatgaacgacgaaaccgcaacggctgattga
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