Pseudomonas aeruginosa PAO1: PA2011
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Entry
PA2011 CDS
T00035
Symbol
liuE
Name
(RefSeq) 3-hydroxy-3-isohexenylglutaryl-CoA/hydroxy-methylglutaryl-CoA lyase
KO
K01640
hydroxymethylglutaryl-CoA lyase [EC:
4.1.3.4
]
Organism
pae
Pseudomonas aeruginosa PAO1
Pathway
pae00280
Valine, leucine and isoleucine degradation
pae00650
Butanoate metabolism
pae00907
Pinene, camphor and geraniol degradation
pae01100
Metabolic pathways
pae01120
Microbial metabolism in diverse environments
pae04146
Peroxisome
Module
pae_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
pae00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00650 Butanoate metabolism
PA2011 (liuE)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
PA2011 (liuE)
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
PA2011 (liuE)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
PA2011 (liuE)
Enzymes [BR:
pae01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.3 Oxo-acid-lyases
4.1.3.4 hydroxymethylglutaryl-CoA lyase
PA2011 (liuE)
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Motif
Pfam:
HMGL-like
Motif
Other DBs
NCBI-GeneID:
878857
NCBI-ProteinID:
NP_250701
UniProt:
Q9I2A0
Structure
PDB
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Position
complement(2199762..2200664)
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AA seq
300 aa
AA seq
DB search
MNLPKKVRLVEVGPRDGLQNEKQPIEVADKIRLVDDLSAAGLDYIEVGSFVSPKWVPQMA
GSAEVFAGIRQRPGVTYAALAPNLKGFEAALESGVKEVAVFAAASEAFSQRNINCSIKDS
LERFVPVLEAARQHQVRVRGYISCVLGCPYDGDVDPRQVAWVARELQQMGCYEVSLGDTI
GVGTAGATRRLIEAVASEVPRERLAGHFHDTYGQALANIYASLLEGIAVFDSSVAGLGGC
PYAKGATGNVASEDVLYLLNGLEIHTGVDMHALVDAGQRICAVLGKSNGSRAAKALLAKA
NT seq
903 nt
NT seq
+upstream
nt +downstream
nt
atgaacctgccgaagaaggtccgcctggtggaggtcggtccgcgcgacggactgcagaac
gagaaacagccgatcgaggtggccgacaagatccgcctggtcgatgacctgagcgccgcc
ggcctggactacatcgaagtgggcagcttcgtctcgcccaagtgggtgccgcagatggcc
ggctcggccgaggtattcgccggcatccgccagcgtcccggcgtgacctacgcggcgctg
gcgccgaacctgaaaggcttcgaggcggcgctggagtcgggagtgaaggaagtggcggtg
ttcgccgccgcgtcggaagccttctcccagcgcaacatcaactgctcgatcaaggacagc
ctggagcgcttcgtaccggtgctggaggcggcgcgccagcaccaggtgcgggtgcgcggc
tacatttcctgcgtgctcggctgtccctacgacggcgatgtcgatccgcgccaggtcgcc
tgggtcgcccgcgaactgcagcagatgggctgctacgaggtgtccctgggcgacaccatc
ggcgtcggcaccgccggcgccacccgccggctgatcgaggcggtggccagcgaggttccc
cgcgagcgcctcgccgggcacttccacgacacctacgggcaagccctggcgaacatctac
gccagcctgctggaaggcatcgcggtattcgacagctcggtggccggcctcggcggttgt
ccctacgccaagggcgccaccggcaacgtcgccagcgaagacgtcctctacctgctgaac
ggcctggagatccataccggggtcgacatgcacgccctggtcgacgccggccagcgtatc
tgcgcggtgctcggcaagagcaacgggtcgcgagcggcgaaagcgttgctggccaaggcc
tga
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