Pseudomonas aeruginosa NCGM 1900: NCGM1900_2246
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Entry
NCGM1900_2246 CDS
T03789
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
paeb
Pseudomonas aeruginosa NCGM 1900
Pathway
paeb00300
Lysine biosynthesis
paeb00550
Peptidoglycan biosynthesis
paeb01100
Metabolic pathways
paeb01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
paeb00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCGM1900_2246 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCGM1900_2246 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCGM1900_2246 (murF)
Enzymes [BR:
paeb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCGM1900_2246 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAP21353
UniProt:
A0A077JQR6
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Position
complement(2324682..2326058)
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AA seq
458 aa
AA seq
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MLEPLRLSQLTVALDARLIGEDAVFSAVSTDSRAIGPGQLFIALSGPRFDGHDYLSEVAA
KGAVAALVEREVADAPLPQLLVRDTRAALGRLGALNRRKFTGPLAAMTGSSGKTTVKEML
ASILRTQAGDAESVLATRGNLNNDLGVPLTLLQLAPQHRSAVIELGASRIGEIAYTVELT
RPHVAIITNAGTAHVGEFGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFDTWKARASGR
PLLTFSLDRPQADFRAADLQRDARGCMGFRLQGVAGEAQVQLNLLGRHNVANALAAAAAA
HALGVPLDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAIDILSGFSGR
TVLVLGDMGELGSWAEQAHREVGAYAAGKVSALYAVGPLMAHAVQAFGATGRHFADQASL
IGALATEQPTTTILIKGSRSAAMDKVVAALCGSSEESH
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgcttgagcctcttcgcctcagccagttgacggtcgcgctggacgcccgcctgatcggc
gaggacgccgtcttttcggcggtttctaccgacagtcgcgccatcgggcccggccaactg
ttcattgccctgagtgggccgcgtttcgacggccacgactatctctccgaggttgccgcc
aagggcgcggtggctgcgctggtggagcgcgaagtcgccgacgcgcccctgccgcaattg
ctggtgcgcgatacccgtgcggccctggggcgactgggcgcgctgaaccggcgcaagttc
accggcccgctggcggccatgacgggctccagcggcaagaccacggtcaaggagatgctc
gccagcatcctgcgtacccaggccggcgatgccgagtcggtgctggctacccgtggcaat
ctgaacaacgacctcggcgtaccgctgaccctgctgcaactggcgccgcagcaccgtagc
gcagtgatcgaactgggcgcctcgcgcatcggcgagatcgcctacacggtcgagctgacc
cgcccgcacgtggcgatcatcaccaatgccggcaccgcccatgtcggcgagttcggcgga
ccggagaagatcgtcgaggcgaagggcgagatactcgaagggctggccgccgacggcacc
gccgtgctgaacctggacgacaaggccttcgacacctggaaggcccgtgccagcggccgt
ccgttgctgactttctccctcgaccggccccaggccgatttccgcgccgccgatctgcag
cgcgatgcgcgcggctgcatgggcttcaggctgcagggcgtagcgggtgaagcgcaggtc
cagctcaacctgctggggcggcacaatgtcgccaatgccctggctgccgccgctgccgcc
catgcactgggcgtgccgctggatgggatcgtcgccgggctgcaggcgctgcagccggtc
aagggccgcgcggtagcgcaactgaccgccagcgggctgcgtgtgatagacgacagctac
aacgccaaccccgcgtcaatgctggcggcgattgatatactgagcggcttttccgggcgc
accgtcctggtcctcggagacatgggcgaactcggttcctgggccgagcaggcccaccgc
gaggtgggcgcctacgccgctggcaaggtgtccgcgctctatgcggtcggaccgctgatg
gcccacgccgtacaggcgttcggcgccacgggccggcacttcgccgaccaggccagcctg
atcggggcgctggccaccgaacaaccgacaaccaccattttgatcaagggttcccgcagc
gcggcgatggacaaagtcgtcgcggcgctgtgcggttcctccgaggagagtcactaa
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