Paenibacillus sp. FSL R5-0912: R50912_25460
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Entry
R50912_25460 CDS
T03334
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
paeq
Paenibacillus sp. FSL R5-0912
Pathway
paeq00300
Lysine biosynthesis
paeq00550
Peptidoglycan biosynthesis
paeq01100
Metabolic pathways
paeq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
paeq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
R50912_25460
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
R50912_25460
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
R50912_25460
Enzymes [BR:
paeq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
R50912_25460
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AIQ42999
UniProt:
A0A089LE02
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Position
complement(5767780..5769192)
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AA seq
470 aa
AA seq
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MITRTLYTIAQMCGGKLSSAEDNNIEIAGVVTDSRKITPACLFVPLVGDNFDGHDYAAAS
LAAGAAATLWQRDKEPAPEGGPVILVEDTLAALQRLSSAYLGELAPRVVAVTGSNGKTTT
KDMVTALLEVQYKVHKTQGNFNNHIGLPLTILSMDSDVEIAVLEMGMSSRGEISLLSRIA
TPDVAMITNVGESHLLQLGSRKEIARAKLEIVDGLKPGGLLIYNGDEPLLAEVMAEPGFN
PPEGMLSFRFGQSGDNDDYPTGLMTHGAGMSFTSHLHAERAFTLPLPGRHNVINALAALA
VARHFLVTDENIETGLAGLKLTGMRIEVIQAANGLTLLNDAYNASPTSMRAAIDVLQSMK
CSGSRIAVLGDMLELGPDEVQFHQQIGSYLDPALTDAVYTYGPLAAHIAAAAAERFGAGH
VFAFEDKEALITALNTKCGSRDVVLFKASRGMRLEEVLHRLKEYSEADLN
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
ttgattacaagaacgctgtatactatcgcgcaaatgtgcggaggaaagctgtcctctgct
gaagataacaatatcgaaattgcgggggtcgtaaccgattcccgcaaaattacgcctgcc
tgcctgttcgttcctctggtcggagataactttgacggccatgattacgctgctgcttct
ctggcggcaggagcagccgctacgctctggcagcgggataaggagcctgcgcctgaaggc
ggtcctgtcattctggtggaggatacactggccgctttgcagagactgtcctcggcatat
ctgggcgagctcgcaccgcgtgtagtcgccgtgacaggcagcaacggcaagacaacgacc
aaagatatggttaccgctcttcttgaagtgcagtacaaggtacacaaaacacaggggaat
ttcaataaccacatcggtctgccgcttacgattctctccatggacagtgatgttgagatt
gctgtgctggagatgggcatgagctcgcgcggggagatatccctgctgtcaaggatagct
acccctgatgtggctatgattaccaacgtgggtgaatcccatctgctgcagctcgggtcc
cgcaaggaaattgcccgggccaagctggagattgtggacggacttaagccgggcggcctg
ctcatctataacggggatgaaccgctgctcgcagaagttatggcagagccggggtttaat
ccgccggaagggatgctcagcttccgtttcgggcagtccggagacaatgatgactatcct
acaggtctcatgactcatggagcaggaatgtccttcacttcgcatcttcatgccgagcgt
gccttcacgttgcctctgccggggcgtcacaatgtcattaacgcactcgccgcactggcg
gttgcacgccacttccttgtgactgatgagaatattgagaccggattagccgggcttaag
ctgaccggcatgcggattgaagtgatacaggcggcgaacgggctgacgctgctgaacgat
gcttacaatgccagccctacgtccatgagagcagcgatagatgtgctgcagtccatgaag
tgcagcgggagcagaatcgcggtgctgggggacatgctggaacttgggcctgatgaagtt
cagttccaccagcagatcggcagctatctcgatcctgcactgacggatgcggtatacact
tacggaccgctcgctgctcatattgctgcggctgcggcggagagattcggggccggacat
gtatttgcttttgaagacaaagaagcattgatcacggccttgaacaccaaatgtggttcc
agggatgtagtactcttcaaagcgtcccgggggatgcgtctggaggaagtgcttcaccgc
ctgaaagaatattctgaagctgacttaaactaa
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