Paraneptunicella aestuarii: KIH87_05285
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Entry
KIH87_05285 CDS
T07748
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
paew
Paraneptunicella aestuarii
Pathway
paew00260
Glycine, serine and threonine metabolism
paew00261
Monobactam biosynthesis
paew00270
Cysteine and methionine metabolism
paew00300
Lysine biosynthesis
paew01100
Metabolic pathways
paew01110
Biosynthesis of secondary metabolites
paew01120
Microbial metabolism in diverse environments
paew01230
Biosynthesis of amino acids
Module
paew_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
paew_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
paew00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
KIH87_05285 (thrA)
00270 Cysteine and methionine metabolism
KIH87_05285 (thrA)
00300 Lysine biosynthesis
KIH87_05285 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
KIH87_05285 (thrA)
Enzymes [BR:
paew01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
KIH87_05285 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
KIH87_05285 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
UAA39773
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All DBs
Position
1262226..1264685
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AA seq
819 aa
AA seq
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MKVLKFGGSSLADADKYLRVKEISLNAHNESGAAVVLSAPKGVTNALAALCEQASKGEDY
GELLGKLSSTLNGIASDLSTQLPNFEFAKMQRFIGEHMEQLGNHLQGMSLLRCSPDAIVA
QIVSLGEYVSVNLFSEILTATGQKNLIVDPVDYVVSEGDYLDSIADLETSKAKFSELNAE
EGAVLIMPGFVAANADGEKVTLGRNGSDYSAAILAACIDADCCEIWTDVDGVYNADPNQV
ESAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQFSIPCLIRNTLNPEAPGTLISHEAS
TQWTQVKGISLLENMSMFNLSGPGMKGMVGMASRVFEVISNANISISLITQSSSEYSISF
CIHSKDSDRALNMLEDSFALELNNKLLEPIEVRNHLAIVTLVGDGMRHTKGLAAKFFSAL
AQARVNNVAIAQGSSERSISTVVEQRKAKKAVKVIHQNFFSNLHTIDAFVVGCGTVGAEL
LSQMNKQQASLLERKISLRVYGIANSKQVLLDSNGIDLASDWQSSLQESSEQLSVAGLRA
FAHDNSLVNPVMIDCTTSDDIASLYIDFMKSGFHVVTPNKKANTNDMAFYKELRKVAQSS
NRQFLYETTVGAGLPVIDNLQKLIYAGDELIQFEGILSGSLSFIFGKMDEGMALSEATQL
ALQKGYTEPDPRDDLSGLDVARKLLIMAREGGLQMELNEIEVESVLPEGFDALGSVDEFM
AKLPQLDELYQQRINKNQQEGKVLRYVGSIKEGKCKVSIIAVDSQHPLYAVKNGENALAI
HSHYYQPIPYVIRGYGAGAAVTAAGVFADVLRTMPWKQV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgaaagttctaaaatttggtggttcctcactggctgatgcagacaagtatctgcgtgta
aaagagataagccttaacgctcacaacgaaagtggtgcagcggttgtgctgtcagcccct
aaaggtgttaccaatgcgttggctgctttatgcgagcaggcttcgaaaggtgaagactat
ggggagttattggggaaattgagcagtaccttaaatggtattgcgagtgatttatcaaca
cagttacccaactttgagtttgccaaaatgcaacgctttattggcgagcatatggagcaa
ctcggcaatcacctgcaaggtatgagcttgttgcgttgcagccctgatgcaatcgtggca
cagattgtcagcctgggtgaatatgtgagtgtgaatctgttctctgaaattctcactgcc
accggccaaaagaatctaatagttgatcctgttgactacgttgtttctgaaggggattat
ctcgacagtatcgccgatttggaaaccagtaaagccaagttttctgaactcaatgccgaa
gaaggtgcagtgcttatcatgcctggttttgttgcggcaaacgctgacggtgagaaagtc
acattaggtcgcaacggttccgattattctgctgctattcttgccgcttgtatcgacgcc
gactgctgtgaaatctggactgacgtggatggtgtttataatgccgatccgaatcaggtt
gaaagtgcggtattgctcgacaagctgacgtatcaggaagccatggagctttcctatttt
ggtgccaaagtgctgcatccgaaaaccatcgggcctatcgctcagttttctattccctgt
ttgatccgtaataccttaaatccggaagcgccgggcaccttgattagccatgaagccagc
actcaatggactcaggtgaaaggtatctctctgcttgaaaatatgagcatgtttaacctg
tctggcccgggaatgaaaggcatggttggtatggcaagcagagtgtttgaagtgatttcc
aatgccaatatctcgatcagcttaatcactcagtcttcctctgaatacagcatcagtttt
tgtattcacagtaaggatagcgatcgtgctttgaatatgttggaagattcttttgctctt
gagctgaataacaaattgttggagccaattgaagtacgtaaccatttggccattgtgact
ttagtgggtgacggtatgcgccacactaaaggtttggctgccaagtttttcagcgcattg
gcgcaagctcgcgtgaacaatgtggctattgctcagggctcgtctgaacgttcgatttca
accgtagttgaacagcgtaaggcgaaaaaagcggtgaaggttattcatcagaattttttc
tccaatctccacaccattgacgcttttgtggtggggtgtggcaccgtaggcgcagaattg
ctgtcgcagatgaacaagcaacaggcgagtttattggagcgaaagattagtttgcgcgtt
tacggtatcgccaatagcaagcaggtgttgctggatagtaatggaattgatcttgcgagc
gattggcagtccagtttgcaggaatcttctgaacagttgtctgtggctggattgagagca
tttgcccatgacaatagcttggtaaatccggtcatgattgattgtacaaccagtgatgat
atcgccagcttgtatattgatttcatgaagtcgggcttccatgtggtaacgccaaataag
aaagccaataccaatgatatggctttctacaaagagttgcgtaaggtggctcaatcctct
aatcgtcagttcttgtatgaaacgacggtgggggcgggattacctgttatcgataacttg
caaaagctgatttacgccggtgacgaactgattcagttcgaaggtattttgtcgggttca
ttgtcgtttatcttcggcaagatggatgaaggcatggcgctttctgaagccactcaactg
gcgttacagaaaggttatactgaacctgatcctcgtgatgatttaagtggccttgatgtt
gctcgcaagctgttgattatggcgcgtgaaggcggtttgcaaatggaattgaatgaaatt
gaagtggagtctgtattgcctgaggggtttgacgcattgggctccgttgatgagtttatg
gcaaagctgcctcaactggacgagctgtatcaacaacgtatcaataagaatcagcaagaa
ggtaaagtattgcgctatgtcggcagtatcaaggagggaaaatgtaaagtgagtatcatt
gcggttgatagtcaacatccactttatgctgttaaaaatggtgagaacgcgcttgcgatt
catagccattattatcagccaatcccttatgttataagaggttacggtgcgggcgcagcg
gtaacagccgcaggtgtttttgccgatgtattacgtactatgccttggaaacaggtataa
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