Cutibacterium acnes SK137: HMPREF0675_5041
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Entry
HMPREF0675_5041 CDS
T01215
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase II
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
pak
Cutibacterium acnes SK137
Pathway
pak00230
Purine metabolism
pak01100
Metabolic pathways
pak01110
Biosynthesis of secondary metabolites
Module
pak_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pak00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
HMPREF0675_5041 (purL)
Enzymes [BR:
pak01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
HMPREF0675_5041 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
ADE00781
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All DBs
Position
complement(2097874..2100114)
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AA seq
746 aa
AA seq
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MENAVSTPDVEQPWAELGLSADEYQRIREILGRRPTGGELAMYSVMWSEHCSYKSSKKYL
RRFGDLPQQTPLGPLLAGIGDNAGVVDIGNGLAVTFKAESHNHPSYVEPHQGAATGVGGI
VRDIMAMGARPVGVMNALAFGPLDAPDTARVLPGVVSGIADYGNCLGLPTIGGQTLFDPT
YYGNPLVNALCVGVLRHEDLQFAKASGVGNLVVLFGAATGGDGIGGASILASESFAAEGE
SKRPSVQVGDPFMEKLLIECTLDLFNAGVVEALQDFGAAGISCATSELASAGDGGMHVEL
DRVPLRDPNLAPEEILMSESQERMAAVVRPDQLDRFMEICAHWGVAATVIGEVTDTGRLH
IDWQGERIVDVDPRTVAHDGPVLDMPAARPWWIDELNENDANALPRDNSGEGLAGALLAL
VGSAQLCDRSWITDQYDRFVRGNTVLAQPNDAGMIRIDDNLGIALSLDANGRQTTLNPYL
GAQLALCEAYRNVAVSGATPVAVTDCLNYGSPYDPDVMWQFDETILGLVDGCRELGVPVT
GGNVSLHNRTGDESIRPTPLVGVLGVIDDVHRRIPSAFAHDGDAVLLLGTTKCEFGGSVY
EDVIHAGHLGGMPPMPDLNAEKALAAVMVEASKRGLLSSAHDLSDGGLAQALVESCLQGG
LGVSVSLPEGEPSVMLFSETPARAIVSLCGNGYREFKELCQEHGVPTARIGEVIDHGEIE
VNGLFSLPLDEIERAWRKPIPTAMGE
NT seq
2241 nt
NT seq
+upstream
nt +downstream
nt
gtggagaacgccgtcagcacccccgacgttgagcagccctgggctgagttggggttgtcc
gccgacgagtaccagcgcatccgggagatcctgggacgccgcccgaccggcggcgagctc
gccatgtactcggtgatgtggtcggagcattgctcctacaaatcatcgaagaaatacctg
cgccgattcggtgacctgcctcagcagacgccgctcggcccgctgctagctggcatcggg
gacaatgctggtgtcgtcgatattggcaacggactggccgtcacttttaaggcggagtcc
cacaaccacccctcctacgtcgagccccaccagggcgcagctaccggagtcggtggcatc
gttcgcgacatcatggcgatgggcgctcgcccggtcggcgtcatgaatgctttggctttc
ggcccgctggatgctccagataccgcacgtgtgctgcccggtgttgtgtctgggatcgcc
gactatggcaactgcctcggcctgcccacgatcggcggccagaccctcttcgaccccacc
tattacggcaatccgctcgtcaacgccctgtgcgtcggggtgctgcgtcatgaggaccta
cagttcgccaaagcctcgggtgtaggcaatctcgtcgttctctttggtgcggccaccggt
ggcgacggtatcggtggcgcgtcgatccttgcctcggaatccttcgctgcagagggcgag
tcgaagcgacccagcgtccaggtgggcgacccgttcatggagaagctgctcatcgagtgc
acccttgacctcttcaacgccggggtagttgaggccttgcaggatttcggtgccgccgga
atctcctgtgccacctccgagctggccagtgctggcgacggtggcatgcacgtcgagctc
gaccgcgttccgctgcgcgacccgaacctcgcccctgaagagatcctcatgagcgagtcc
caggagcggatggccgcggtggtgcgccccgatcagcttgaccgcttcatggagatctgc
gcccattggggtgtcgctgccactgtcattggcgaggtcaccgacaccggtcgacttcac
attgattggcagggcgagcggattgtcgacgtcgatccgcggacggttgctcacgacgga
ccggttctcgacatgccggccgcccgtccgtggtggattgatgagctcaacgagaacgac
gccaacgcgttgccgcgcgataactctggtgagggtcttgccggggccctgctggccctt
gttggctccgcccagctgtgcgaccgttcctggatcaccgaccagtatgaccggttcgtg
cgtggcaatactgtgctcgctcagccgaacgatgccggcatgattcgtattgacgacaac
ctcggcatcgcgctgtccttggacgctaacggacgccagaccacccttaacccgtatctt
ggcgcccagctggctctttgcgaggcttaccggaatgtggctgtctctggcgcaactccg
gtggctgtcactgattgcctcaattatggctccccgtacgatcccgatgtcatgtggcaa
ttcgacgagaccatccttggtctggttgacggctgccgcgagcttggcgtgccggttacg
ggcggtaacgtttccctgcacaaccgcactggagatgagtcgattcggcctactccgctc
gttggtgtgctcggcgttattgatgacgtgcatcgtcgcatcccgtcggccttcgcacac
gacggcgacgctgtcttgctgctaggaacgacgaagtgcgagttcggcggatcggtctat
gaggacgtcatccacgctggccacctaggcggtatgcccccgatgcccgacctgaatgcc
gagaaggccctggccgcggtgatggtggaagcgtcgaagcgcggcctgctgtctagcgcc
cacgacctgtccgacggtggcctggcacaggcgcttgtggaaagctgcctacaggggggt
cttggcgtgtcggtgagtctgcccgagggcgaaccatcggtgatgttgttctcggagacc
ccggcccgagcgatcgtctcgctgtgcggtaacggctaccgtgagttcaaggagctgtgc
caggagcacggtgtgccgactgcccgtattggcgaggtcatagatcacggtgagatcgag
gttaacggtctgttcagcctcccccttgacgagatcgaacgagcctggcgcaagccgatt
ccaactgctatgggggagtga
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