Cutibacterium acnes SK137: HMPREF0675_5053
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Entry
HMPREF0675_5053 CDS
T01215
Symbol
purC
Name
(GenBank) phosphoribosylaminoimidazolesuccinocarboxamide synthase
KO
K01923
phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:
6.3.2.6
]
K23264
phosphoribosylformylglycinamidine synthase subunit PurS [EC:
6.3.5.3
]
Organism
pak
Cutibacterium acnes SK137
Pathway
pak00230
Purine metabolism
pak01100
Metabolic pathways
pak01110
Biosynthesis of secondary metabolites
Module
pak_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
pak00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
HMPREF0675_5053 (purC)
Enzymes [BR:
pak01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase
HMPREF0675_5053 (purC)
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
HMPREF0675_5053 (purC)
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Gene cluster
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Motif
Pfam:
SAICAR_synt
PurS
Motif
Other DBs
NCBI-ProteinID:
ADD99638
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Position
complement(2113375..2114637)
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AA seq
420 aa
AA seq
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MVTSHLNLPLLAEGKVRRLYRLPDQPGRLLMVATDRISAYDHVLTPDVPGKGAILTNMSL
WWFDQLADIVDNHLVSVDVPAEVAGRAMVVEELDMFPVECVVRGYLTGSGWAEYQRNQAV
CGIRLPEGLQNGSRLEEPIFTPAIKAPQGEHDENIDYLRLVELVGPDVAAQLHDLSLRVY
QRAEEIARKRGILLADTKLEFGRRVDGTIVLADEVLTPDSSRFWDAETWQPGKGADSFDK
QYVRDWLTNESGWDRASDQEPPALPEEVVKATSRRYEEAWARLTGGHVSDEVSDETPHNE
ADDDKHARASRDSVSGESGDAAPVALDVPGESESCSADKIGAMSRVVVEVMPKPEILDPQ
GKAITSVLARLGHDGLTVRQGKRFEITGEGLEDRLDEIRQVASELLANTVIESFDVHVED
NT seq
1263 nt
NT seq
+upstream
nt +downstream
nt
atggtcacttcgcacctcaatcttccattgctggctgagggcaaggtccgacgcctctat
cgtcttcccgatcagccgggccgcctgcttatggtcgctacggaccggattagcgcctac
gaccacgtcctgacccccgatgttcccggcaagggagccatcttgacgaatatgtccttg
tggtggttcgaccaattggccgacatcgtcgataaccatctcgtgagcgtggatgtcccc
gccgaggtcgcagggcgcgccatggtcgttgaggaactcgacatgttcccggtcgaatgc
gtcgtgcggggctacctcaccggttcagggtgggccgaatatcagcgcaaccaggccgtg
tgcggaatccgccttcccgaggggctgcagaatgggtcccggctcgaagagcccattttc
accccggcaattaaggccccgcagggagaacatgacgagaacatcgactatctacgcctg
gtagaactcgtcggtcccgatgttgcagcgcagctgcatgacctttcgctgcgggtctac
cagcgtgcagaggagatcgctcggaagcgaggcatcctcctggccgataccaagcttgaa
ttcgggcgtcgtgtcgacggcaccatcgtgctagctgacgaggtgcttacccctgattct
tcgcgattctgggacgctgagacgtggcagcccggcaagggggcagattccttcgataag
caatatgtgcgcgattggctcacgaatgagtccggttgggatcgcgctagtgaccaggag
ccgcctgccctcccagaggaggtcgtcaaggccaccagtcggcgttatgaggaggcctgg
gcacgtctgactggcgggcacgtgtctgatgaggtcagcgatgagacgcctcacaatgag
gccgacgatgacaagcacgcgagggcttcgcgggatagcgtttccggggagtccggggac
gctgcaccggtggccctcgacgttcctggcgagtcggagtcctgtagtgccgataagatc
ggggctatgtcacgtgtagtggtggaggtcatgccgaaacccgaaatcttggatccccag
ggcaaggccatcacgtcggtgctcgctcggcttggccatgacggcttgacggtgcgccag
ggtaagcgtttcgagatcactggtgagggtttggaagatcgtctcgacgagatccgtcag
gtggcctctgagctgttggccaacaccgtcattgaatccttcgacgtgcacgtggaggac
tga
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