Pteropus alecto (black flying fox): 102880608
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Entry
102880608 CDS
T02993
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale00790
Folate biosynthesis
pale01100
Metabolic pathways
pale01240
Biosynthesis of cofactors
pale01523
Antifolate resistance
pale04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
102880608 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
102880608 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
102880608 (FPGS)
Enzymes [BR:
pale01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
102880608 (FPGS)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Microp_apicomplexa_9
Motif
Other DBs
NCBI-GeneID:
102880608
NCBI-ProteinID:
XP_006918055
UniProt:
L5K8X7
LinkDB
All DBs
Position
Unknown
AA seq
580 aa
AA seq
DB search
MSRARSHLRAAFFLTAVSPRGATSWIAARRELSARPAPQEPGMEYQDAVRTLNTLQTNAS
YLEQVKRQRGDPQKQLEAMELYLARSGLQVEDLDRLNIIHITGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETEDSNSCVSMPAYFR
FLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIVRKPVVCGVASLGIDHTSLLGDTVEKI
AWQKGGIFKRGVPAFTVLQPDGPLAVLRERAEQTSCPLYLCPPLEALEEGGPPLTLGLEG
EHQRSNAALALQLAHCWLQQKDHRGVGEVKATRPSLLRQLPLAPVFQPTPHMRRGLRDTE
WPGRTQVLRRGPLTWYLDGAHTSSSVQACVRWFRQALHRCKEPGSGTEVRVLLFNSTGDR
DAAALLKLLQPCQFDYAVFCPNLTEVSSTDNADQQNFTVTLDQVLLRCLEHQQHWSRLDE
EQACPEPGGPTSLLLAPRPAHSHSTSSLVFSCISQALQWISQGRDPVFQPHSPPRGLFTH
PVAGSGANVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1743 nt
NT seq
+upstream
nt +downstream
nt
atgtcgcgggcacgcagccacctgcgcgccgctttcttcctgacagcagtttctccgcgc
ggtgcaacgtcctggatcgcggcgcggcgagagttgagcgcgaggcccgcgccgcaagag
ccgggcatggagtatcaggatgctgtacgcacactcaacacccttcagactaatgccagc
tacctggagcaggtgaagcgccagcgaggtgacccccagaaacagctggaagccatggag
ctatacttggcacggagtgggctgcaggtggaggacctggaccggctgaacatcatccat
atcactgggaccaaggggaagggttccacctgtgccttcactgaacgtatcctccgaaac
tatggcctgaagacaggattctttagctctccccacctggtgcaagtgcgtgagcggatt
cgcatcaacgggcagcccatcagccctgagctcttcaccaagcacttctggcgcctctac
caccggctggaggagaccgaggatagcaacagctgtgtctctatgcccgcctacttccgc
ttcctcacgctcatggccttccacgtcttcctccaagagaaggtggacctggcagtggtg
gaagtgggtatcggtggggcttacgactgcaccaacattgtcaggaagcctgtggtgtgt
ggggtcgcttcccttggcatcgaccacaccagccttctgggggacacggtggagaagatt
gcatggcagaaagggggcatcttcaagcgtggtgttcctgccttcactgtgctccagcct
gacggtcctctggcagtgctgagggagcgcgccgagcagacctcatgtcccctctacctg
tgcccaccgctggaggctctggaggaaggggggccgccgctaaccctgggtctggaggga
gagcaccagcggtccaatgctgccttggccttgcagctggcccactgctggctgcagcaa
aaggaccaccgaggtgtcggggaggtgaaggcgaccaggccaagcctcctgcggcagcta
cctctggcacctgtgttccagcccacaccccacatgcggcgcgggcttcgggacaccgag
tggccgggccggactcaggtgctgcggcgcgggcccctcacctggtacctggatggtgcg
catacctccagcagcgtgcaggcctgcgtgcgctggttccggcaggcgctgcaccgctgc
aaggagcccggcagcgggactgaggtgcgtgtcttgctcttcaactctaccggggaccgg
gatgccgcggccctgctgaagctgctgcagccctgccagttcgactatgctgttttctgc
cctaacctaacagaggtgtcatccacggacaacgcagaccagcagaacttcacagtgaca
ctggaccaggtgctgctccgctgcctggaacaccagcagcactggagccgcctggatgag
gagcaagcctgtccggagcctggcgggcccacgtccttgctgctggcaccccgcccagcg
cacagccacagcaccagctccctcgtcttcagttgcatctcccaagctttgcagtggatc
agccaaggtcgggaccctgtctttcaaccacacagtcccccacggggcctcttcacccac
cctgtggcaggcagcggggccaacgtactccgtgaggctgctgccatccacgtgctggtc
acgggaagcctgcacctagtgggtggtgtcctgaagctgctggagccttccctgtcccag
tag
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integrated database retrieval system
