KEGG   Pteropus alecto (black flying fox): 102880759
Entry
102880759         CDS       T02993                                 
Symbol
TGFBR1
Name
(RefSeq) TGF-beta receptor type-1 isoform X2
  KO
K04674  TGF-beta receptor type-1 [EC:2.7.11.30]
Organism
pale  Pteropus alecto (black flying fox)
Pathway
pale04010  MAPK signaling pathway
pale04060  Cytokine-cytokine receptor interaction
pale04068  FoxO signaling pathway
pale04144  Endocytosis
pale04218  Cellular senescence
pale04350  TGF-beta signaling pathway
pale04371  Apelin signaling pathway
pale04380  Osteoclast differentiation
pale04390  Hippo signaling pathway
pale04520  Adherens junction
pale04659  Th17 cell differentiation
pale04926  Relaxin signaling pathway
pale04933  AGE-RAGE signaling pathway in diabetic complications
pale05142  Chagas disease
pale05161  Hepatitis B
pale05166  Human T-cell leukemia virus 1 infection
pale05200  Pathways in cancer
pale05210  Colorectal cancer
pale05212  Pancreatic cancer
pale05220  Chronic myeloid leukemia
pale05225  Hepatocellular carcinoma
pale05226  Gastric cancer
pale05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pale00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102880759 (TGFBR1)
   04350 TGF-beta signaling pathway
    102880759 (TGFBR1)
   04390 Hippo signaling pathway
    102880759 (TGFBR1)
   04371 Apelin signaling pathway
    102880759 (TGFBR1)
   04068 FoxO signaling pathway
    102880759 (TGFBR1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    102880759 (TGFBR1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102880759 (TGFBR1)
  09143 Cell growth and death
   04218 Cellular senescence
    102880759 (TGFBR1)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    102880759 (TGFBR1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    102880759 (TGFBR1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    102880759 (TGFBR1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    102880759 (TGFBR1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102880759 (TGFBR1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    102880759 (TGFBR1)
   05212 Pancreatic cancer
    102880759 (TGFBR1)
   05225 Hepatocellular carcinoma
    102880759 (TGFBR1)
   05226 Gastric cancer
    102880759 (TGFBR1)
   05220 Chronic myeloid leukemia
    102880759 (TGFBR1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    102880759 (TGFBR1)
   05161 Hepatitis B
    102880759 (TGFBR1)
  09174 Infectious disease: parasitic
   05142 Chagas disease
    102880759 (TGFBR1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    102880759 (TGFBR1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    102880759 (TGFBR1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pale01001]
    102880759 (TGFBR1)
Enzymes [BR:pale01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.30  receptor protein serine/threonine kinase
     102880759 (TGFBR1)
Protein kinases [BR:pale01001]
 Receptor serine/threonine kinases (RSTK): TKL group
  TGFBR1 family [OT]
   102880759 (TGFBR1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr TGF_beta_GS Activin_recp Pkinase_fungal APH Haspin_kinase FTA2
Other DBs
NCBI-GeneID: 102880759
NCBI-ProteinID: XP_006911601
LinkDB
Position
Unknown
AA seq 434 aa
MCIAEIDLIPRDRPFVCAPSSKMGSVTTTYCCSQDHCNKIKLPTGGKPSPGLGPVELAAV
IAGPVCFVCISLMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDLIYDMTTSGS
GSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREERSWFREAEIY
QTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVEGMIKLALST
ASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDSATDTIDIAP
NHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGIHEDYQLPYY
DLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGAARLTALRIK
KTLSQLSQQEGIKM
NT seq 1305 nt   +upstreamnt  +downstreamnt
atgtgtatagctgaaattgacctaattcctcgagataggccatttgtatgtgcaccgtct
tcaaaaatggggtctgttactacaacatactgctgcagtcaggaccactgcaataaaata
aaactcccaactggcggaaagccatcacctggccttggtcctgttgaactggcagctgtc
attgctggaccagtctgctttgtctgcatctcactcatgttgatggtgtatatctgccat
aaccgtactgtcattcaccatcgtgtgccaaatgaagaagatccttcattagatcgccct
tttatttcagagggtactacattaaaagatttaatttatgatatgacaacatcaggttct
ggatcaggtttaccattgcttgttcagaggacaattgctagaactattgtgttacaagaa
agtattggcaaaggtcgatttggagaagtttggcgaggaaagtggagaggagaagaagtt
gctgttaaaatattctcctctagagaagaacgctcatggttccgtgaggcagagatttat
caaactgtaatgttacgtcatgaaaacatcttgggatttatagcagcagacaataaagac
aatggtacatggactcagctctggttggtgtcagattatcatgagcatggatcccttttt
gattatttgaatagatacacagtcactgtggaaggaatgataaaactcgctctgtccaca
gcaagtggacttgctcatcttcacatggagattgttggtacccaaggaaaaccagccatt
gctcatagagatttgaaatcaaagaatatcttggtaaagaagaatggaacttgctgtatt
gcagacttgggactggcagtaagacatgattcagccacagatacaattgatattgctcca
aaccacagagtgggaacaaaaaggtacatggcccctgaagttctagatgattccataaat
atgaaacacttcgaatccttcaaacgtgctgacatctatgcaatgggcttagtattctgg
gaaatagctcgacgatgttccattggtggaattcatgaagattaccagctgccttattat
gatcttgtaccttctgatccatcagttgaagaaatgagaaaagttgtttgtgaacagaag
ttacggccaaatattccaaacagatggcagagctgtgaagccttgagagtaatggctaaa
attatgagagaatgttggtatgccaatggagcagctaggcttacagctttgcggattaag
aaaacattgtcacaactcagtcaacaggaaggcatcaaaatgtaa

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