Pteropus alecto (black flying fox): 102882991 Help Entry 102882991         CDS       T02993                                  Symbol SETX Name (RefSeq) probable helicase senataxin   KO K10706   ATP-dependent RNA/DNA helicase, senataxin [EC:5.6.2.5 5.6.2.3] Organism pale  Pteropus alecto (black flying fox) Pathway pale05014   Amyotrophic lateral sclerosis Brite KEGG Orthology (KO) [BR:pale00001]  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     102882991 (SETX)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03021 Transcription machinery [BR:pale03021]     102882991 (SETX) Enzymes [BR:pale01000]  5. Isomerases   5.6  Isomerases altering macromolecular conformation    5.6.2  Enzymes altering nucleic acid conformation     5.6.2.3  DNA 5'-3' helicase      102882991 (SETX)     5.6.2.5  RNA 5'-3' helicase      102882991 (SETX) Transcription machinery [BR:pale03021]  Eukaryotic type   RNA polymerase II system    Other transcription-related factors     Transcription termination factor      102882991 (SETX) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AAA_11 AAA_12 AAA_19 UvrD-helicase AAA_30 AAA_22 ResIII SLFN-g3_helicase AAA_16 NAT10_TcmA_helicase nSTAND3 TniB UvrD_C_2 Motif Other DBs NCBI-GeneID:  102882991 NCBI-ProteinID:  XP_006918235 LinkDB All DBs Position Unknown AA seq 2668 aa AA seqDB search MSTCCWCTPGGVSTVDFLKLYASETPSSAFQTADEDLCYCLECVAEYHKARDELPFLHEV LWELETRRLIIHFEKSMRAEIEDDDELYIVDNNGEAQLFDFTGQDFENKLRVPLLEILKY PYLLLHARVNELCVEALCRMEQANCSFQVFEKHPGVYLFLVHPNEMVRRWAILTAKGLGK VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLVLLPSHMYDTTNYKNYWLG ICMLLTILEEQAMDSLLLGSDKENDFMQLILHTMERQSDDDSGDPFWPALHCFMVILDRL GSKVWGQLIDPIEAFQTIINNRSYNREIQSIRNSSVRTKLEPESCMDDMVTCSQIVYNYN PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD LKDLGVAYIVEVIHHLHSEVKDVLNQTVVVCDKVTEFFFLILVSVIELHRNKKCLHLLWV SSQQWVEAVVKCAKLPTTAFARSSEKSSGSGSKGTPMISSLSLHSMPSNSVQLACVQLIR SLLKEGYQLGQQRNLSLGWQLTSQETQELQTCLKQIIRNIKFKVPQCSAIVDLTPPCKIL PASCDKEENEQVGKKCKNMLCVESSSPTFSKEPMKADAYQLQESILSKASSAVEEDNEPN YIKDLKLEDHLSAESCLKQSSKNLFAGRAQDQVKMRTGKQKSVKDSSLYTSKNCTARNGP ERGCGRGIILSTHSPTDSSADTQEKMSTSNGDFSSKDGVLGKTSKAKSKAQKDEICAKLS CVIKKPHRKNTSVNSSVKFEGNLAASNVENFCSKKDAGGQKGDSFMHSLSSGSDSILDNK NGEQKAHNSLLLKKKQVKSEELDVSSHENDCQIQECDVGNKDLVLLTETTNTFMHKTSPF KSPGTVLESREKRVSKNTDFREQAPSISPKSDTLTDSQVDRDLHKLSLIAQASVIKFPSD SNQRSSSQLQRKVKDKRSFTANQSNVGDTCRGQIIIISDSDDDDEDADERILEFEKLKHI KQDKVSIKKEGPGPRTSEAHTNTERKPIKEEKPASPLEFEECDSQVFEFESQHEVFSVWQ DQKTDDSSVAEDGKSAYLTHIVDITNDWGYETDYPVSEEVAEVTKDIENAEPRSSRVSVE KFCEIEVRKSKRKQFGKPVAEDPLRPSSSARNEDQSDILNERELTENDLKIADVRTTTPD ARVQRATAAALKKSPPKLRAYSKPIRRVPVSKAAKKTHSDARKGQSKSSNYISCRTTPAI VPPKKFRQCPEPTSTVEKLGLKKAPRRAFELSQRSLEYIVQLRDHGKTVGVVDTRKKTKL ISPQTLPVKNKKLLANQDLQLRRQVRPKSQQNRQGVFDCESTDAARAGPDAAQIPDVFVA ESARSDCSNKAGAEVIASSNGRQSVTCVSSEQEPVKAKFISQETEDPCPLNQRECVMANG GILTHERVLSTSEDPVGGGDLTTPHLDVATLNKGEPASNSDMEEDNIFLTQCDPEDMDLC SQMQQNDNDKLIEVVHGKDTVQIGEDSLSRPPLESLSSTKCKYRDCAETLKNQGEYCSKH CEAKAADEDVFRKPGLPLSAAKPLRPSTTKIFSSSSTSRIAHLSRSLEKASALLPGLKNK SNGAQSVLKAPPPAPLAPPQKPVVEVKSLCNILNSPPSNNSSRQGYRLLFSESRPFSSSP VNMLLSSQSISDAFVKEILKWKYEMFLNFDQCGPPASLCQSISRPVPVRFQDCGDYFDVF FPLMILNTFETVAQEWISSPNKEKFYQLHLRKFPADYKKYWELVVYLDEGELAKQLHPKE NDLVFLVPGTLNGEEHGLEHSLLQEPHEPYCGYVHKFRRTSVMRNGKAECCLSIQTQDNV AVNLSEFVKCTVISSLVTTQRKLKAMSLLSGRNQLARAILNPNPMDFCTKDLLTTTSERI TLYLKDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPGTGKSKTIVGLLYRLLTENQRR GHPDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKEKCKDKKNPLGNCGDINLVRLG PEKSINNEVLKFSLDSQVNHRMKKDLPSYVQEMHKRKEYLDHQLDDLSRQRALCRGGREI QRQELDEKIARVSKERQELASKIKEVQGRPQKTQSNVILESHIICCTLSTSGGLLLESAF RGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVGDPKQLPPTVISMKAQEYGYEQ SMMARFYKLLEENVEHNVVGRLPVLQLTVQYRMHPDICLFPSNYIYSRSLKTNRLTETIR CSSDWLFQPYLVFDVGDGAERRDNDSYVNVQEIKLVMEIIKLIKDKKKDVSFRNIGIITH YKAQKMMIQKELDKEFDGKGPAEVDTVDAFQGRQKDCVIVTCVRANAMQGSIGFLASLQR LNVTITRAKYSLFILGHLRTLMENQHWNHLIQDAQKRGAIIKTCDKNYKHDAMKILKLKP VLTRSLTHPLTVTPEVARPQGGDLPGTKLDGTFTKVAFALSLCHVASDSKEALATLAAKD SERPPAKDQPRDPRLFRRMGVSPETKGKCLQDPQPLSPQYPGATPPLGEPGCVSPQALGS LAEQPSATGSSHRPRVPSEPPAAGTDAASDQRKCDQEGEHGHRRETRASSEGNQERRGPA GRHTKRNSSWDGRVPEREDRSSKKRKLP NT seq 8007 nt NT seq  +upstreamnt  +downstreamnt atgagcacatgctgttggtgtacgccaggtggcgtttccaccgtcgacttcctgaagctc tatgcatccgagaccccatccagtgcatttcagaccgccgacgaagacctctgctactgc ttggagtgtgtggccgagtaccacaaggccagggatgagctgccgttcttgcacgaggtt ttatgggaattagaaacccgacgtctcataattcattttgaaaaatccatgagggcagaa atcgaagatgatgatgaattatacatagtggacaacaatggagaggcacagctgtttgac tttactggccaagactttgaaaataagcttcgggttcctcttcttgaaatcctgaaatat ccttatctgctcttacacgcacgtgttaatgaattatgcgttgaagcactttgtcggatg gaacaggccaattgctcctttcaggtttttgaaaagcatcctggggtctatttgtttttg gtccatcccaatgaaatggttcggcgctgggccatcctgaccgcaaaaggcctggggaaa gtggacagggacgattactatgacttacaggaggttttgacttgcctctttaaagtcatc gagttggggcttttagaaagtccagacatttatacttcctctgtcctcgagaagggtaaa ctggttcttctgccctcacacatgtatgatactacaaactacaaaaactattggctaggt atctgcatgttgcttaccattcttgaagagcaggccatggattcactgttgttgggctcg gacaaagagaacgattttatgcagttgatacttcacaccatggagaggcagtcagacgac gatagtggggatcctttctggccagcgttacactgtttcatggtgattctggatcgcctt ggatccaaggtctgggggcagctcattgaccctatcgaggcatttcaaaccatcatcaac aaccggagctacaaccgagagatccagagtatccggaacagctctgtgaggaccaagtta gaaccggagtcgtgtatggatgatatggtgacttgcagccagattgtatacaattataat cctgaaaagaccaaaaaggattcaggctggagatcagccatttgcccagattattgccct aacatgtacgaagagatggaaacattagccagcgtgcttcaatcagacatcggtcaagac atgcgtgttcacaacagcacattcctgtggttcattccgtttgttcagtccctcatggat ctgaaggatctgggcgtggcctacatagtagaggttatccatcatctgcactcggaagtc aaagatgtcctcaaccagacagttgtcgtgtgtgacaaagtcactgaatttttttttcta attttggtgtcagtgatcgaactacataggaataaaaaatgcttgcatttgctgtgggtg agctcccagcagtgggtggaggctgtcgtgaagtgtgccaagctcccgaccactgccttt gcacggagctcagagaagtcatccggcagcggctccaaaggaacaccgatgatatcatct ctgtctctccattcaatgccatctaactccgtacagctcgcttgtgtgcagctgattaga agtctccttaaagaaggttaccagcttgggcagcagaggaacttatctctaggctggcag ttgactagtcaggaaacccaggagttgcaaacttgtttaaagcaaatcattagaaacatc aaattcaaagtaccacaatgtagcgctattgtggacctgactcctccatgtaagattctt ccggcatcttgtgataaagaagaaaatgagcaagtagggaagaagtgtaaaaacatgctc tgtgtggaaagttccagcccaacgttttctaaagaaccaatgaaagctgacgcgtatcaa ctgcaagagagtatcttgagcaaagcaagtagcgctgtggaagaggataatgagccaaat tacattaaagatttgaaactagaggaccatctctcagctgagtcatgcttaaagcagagt agtaaaaaccttttcgctggaagagctcaagatcaagttaaaatgcgtacggggaagcaa aagtctgtcaaagacagttctttatacacatcaaagaactgtactgcaaggaatggtcca gaaagaggatgtggcagaggaataatactgtcaacacattcgccaactgattctagcgct gatactcaggagaagatgtccacatcaaatggggatttctcttcgaaggatggtgttctt ggcaaaacttcaaaagcaaaatctaaggcccagaaagatgaaatctgtgctaagttatcg tgtgtaataaagaagccacacaggaaaaacacctcggtcaatagttctgtgaagttcgaa ggaaacctggccgcatctaacgttgagaatttctgttcaaagaaagacgcaggaggtcag aaaggggatagcttcatgcacagtctctcttcaggctccgacagtattctggataataaa aatggagaacaaaaagctcataacagtttattgctgaaaaagaaacaggtgaagagtgaa gagttagatgtttcttctcatgaaaatgattgtcaaatacaggaatgtgatgtcggcaat aaagatttggtcctacttacagaaacgaccaacactttcatgcataaaacatctccattt aaaagtcctgggactgtacttgaatcaagagagaagagagtcagcaagaatactgacttt agagaacaggcccctagcatcagccctaagtctgacaccttaacagattctcaggtagac agagacctccacaaattatctctaatagctcaagccagtgtcattaaatttccatcagat tcaaatcaaagaagctcatcccagctacaaagaaaagtgaaagacaaaagaagtttcaca gccaaccaaagtaatgtcggggacacctgccgtggtcaaattattattatttcagattcc gatgatgatgatgaagatgctgatgaaagaattctggagtttgagaaattaaaacacatt aaacaagataaagtaagcattaagaaagaaggcccagggccgcgtacatcagaagctcat acgaacacagaaaggaagccgatcaaagaagagaagccagcttcccctttagagtttgag gagtgcgactcgcaggtgttcgagtttgaaagccaacatgaagtgttttcagtctggcaa gatcagaaaacggacgacagttcagttgcagaggacggaaagagcgcctacttgactcac attgtcgatatcacaaatgattggggctacgagacagattatccagtttctgaagaagtt gccgaagtcaccaaggacatcgaaaatgcggagccacggagcagtcgtgtttccgttgag aaattttgtgaaattgaagtaagaaaatctaagagaaaacaatttggaaagcctgtggcc gaagatcctttaaggccttcgtcttctgccagaaatgaggaccagtctgacatcctcaac gagagagagctgactgaaaacgatcttaaaattgcagacgtgcggacgacgacccccgat gcgcgtgtccagcgggccaccgcggccgccctgaagaagtccccgcccaagctgcgcgcc tactccaaacccatccggagggtccccgtgtccaaagccgcaaagaagacacattcggat gccagaaaggggcagagtaaaagttcaaattacataagctgtaggacaactcctgccatc gtgccaccaaagaaatttcgccagtgtcctgaacccacctccacggttgagaagctgggt ctgaaaaaggctccccgcagggcgtttgagctgtctcagcggtctttggagtacatagtt cagctgcgtgaccatggcaaaaccgttggcgtcgtcgacacccgaaaaaagactaaattg atttctcctcagactcttcctgtcaaaaataagaaactgcttgcaaatcaagatcttcag ttgcgaaggcaggtgagacccaaatcacagcaaaacagacaaggagtttttgactgtgaa agcacagatgccgcgagagcgggcccagatgcggcacagattcctgacgtgttcgtagca gaatcagctaggtcagattgtagtaacaaagcgggagctgaggtcatcgccagcagtaat ggaagacagtcagtgacatgcgtgtcttccgaacaagagcccgtgaaagcgaaattcatt tcccaggagaccgaggatccttgtcccttaaaccagcgtgagtgtgtcatggcaaatgga gggatcctgacgcatgaaagagttctctctacttcagaggaccctgtaggtggaggtgac ctaacgacacctcatttagacgtggcaactttgaacaagggagagcccgcatccaacagt gacatggaggaagataatatatttttaacccagtgcgatcctgaagatatggatttatgt tctcagatgcagcagaatgataatgacaaactcattgaagtagttcatggaaaagataca gtccagataggagaagattcactcagtcggcctcccttggagtctttgagcagcacaaaa tgtaagtacagagattgtgccgaaactctgaaaaaccagggcgagtactgctcgaaacac tgcgaagccaaagcagcggatgaagacgtgtttcggaagcccggcctgcccctttccgcg gctaaacccctgagaccgtccacgacgaagatttttagctcgagtagtacctcacgaatt gctcatctttcccgctctttggaaaaagcctccgcgctcctcccaggtttaaaaaataag tcaaacggggcacagtccgttttgaaagcgccaccgccagcccctctggcgcctcctcag aagccagtggttgaagtgaagagtttgtgcaacattcttaattctccaccttcgaataat tccagcaggcaaggttacagacttctgttcagtgaaagcagacctttttcttcttctccg gtaaacatgctcttgtcatcacagtccatctccgatgccttcgtgaaagagatcctcaaa tggaagtatgaaatgtttttgaacttcgatcagtgcgggcccccagcaagtctctgtcag tccatctcaagacctgtgcctgtcaggtttcaagactgtggagattattttgatgtgttt ttccctttgatgatattgaatacctttgaaacagtagcacaggaatggatcagctctcca aataaagaaaaattctatcagctgcatttacgaaaatttcctgcagattataaaaaatac tgggagctcgtggtttatcttgatgaaggcgaactagctaaacagctccacccaaaggag aacgatttggtgtttttggtccctggaacactgaacggagaggagcacggcctggagcac agcctcctgcaggagccgcacgagccttactgtggttatgtgcacaagtttcgccgcact tcagtcatgcgtaatgggaaagctgagtgttgcctttccatccagactcaagataacgtg gcggtcaacttaagtgaatttgtgaaatgcactgtaatcagttctctggtaactacacaa aggaagttgaaagccatgtctttgttgagtggtcggaaccaactggctagagctattctg aatccaaaccccatggacttctgtacaaaagatttactgacgacaacatctgagagaatt accctctacttaaaagatttcaatgaagaccaaaagaaagccatagaaactgcatatgcc atggtgaaacactccccatctgtcgccaagatctgtctgattcatggaccacctggaaca ggaaaatcaaaaaccattgtcggcctgctgtaccgcctgctgacggagaaccagaggagg gggcatcccgatgaaaactccaacgccaagatcaagcagaaccgcgtcctggtgtgcgcg ccttccaacgcggccgttgatgagctcatgaagaaaatcatcctcgaattcaaagagaaa tgtaaagacaagaagaatcctttgggaaactgtggagatataaacttagtacgtctgggt ccagaaaagtctattaataatgaagtcctgaaattcagcttggacagccaggttaaccac agaatgaaaaaagacttaccttcttatgtccaggagatgcacaaaagaaaggaatatctg gatcatcaactcgatgacctttcccgccagcgtgctttatgccgaggtgggagggaaata cagagacaagaactagacgaaaaaattgccagagtttcaaaagaaaggcaggaacttgct tctaaaattaaagaggttcaaggccgcccacagaaaacacagagcaatgtcatcttggag tcccacatcatctgctgcacactgagcacaagtggtggtttattgctcgagtccgctttt cggggacagggaggggttcccttcagttgcgtcattgtcgatgaggccgggcagtcttgc gaggtggaaaccctcaccccgctcatccatcgctgcaacaagcttatcctcgtgggggat cccaagcagctccctcccaccgtcatctctatgaaggcccaggagtatggctacgagcag tcgatgatggcccgcttctacaaactgctggaggagaatgtggagcacaacgtggtgggc aggctgcccgtgctgcagctcaccgtccagtaccgcatgcacccggacatctgcctcttc ccgtccaattacatctacagcagaagcctgaagacgaacaggctgacggagaccatccgg tgctcgtcagactggctgttccaaccctacttggtgttcgacgtcggagacggcgcagag agacgggacaacgactcgtatgtaaatgttcaagaaataaaactggtaatggaaataatt aaacttattaaagacaaaaaaaaagatgtctctttccgaaacatcggcatcataacgcat tacaaggctcagaagatgatgattcagaaggagttggacaaagaatttgatggaaaaggg ccagcagaagtagatactgtggatgcattccagggtcgtcagaaagattgtgtcattgtc acgtgtgtcagagcgaatgccatgcaaggctcaatcggatttctggcaagtttgcagaga ttgaacgtcaccattacacgagccaagtacagcctcttcatcctcggacacttgaggacc ctgatggagaaccagcactggaatcacctgattcaggacgcacagaagcgtggtgccatt atcaagacctgcgacaaaaactacaagcacgacgcaatgaagatcctgaaactcaagccc gtgctgacgagaagtctgacgcaccctctgaccgtcacccctgaggtggccagaccccag ggcggcgacctgcccggcaccaagctggacggcaccttcaccaaggtagcttttgctttg tctctgtgccacgtagcctctgactccaaggaggctcttgcgactcttgctgcaaaggac tcagaaaggccgcctgcgaaggaccagcctcgcgacccacggctttttaggaggatgggc gtgagccctgaaaccaaagggaagtgcctgcaggacccacagcccttgagcccccagtat cctggagccacgcctcccctgggggagccaggctgcgtgagtccccaggctctgggcagc ctcgcagagcagccctctgccaccggcagcagccacagacctcgcgtgccgagtgaacct ccagccgctggcaccgatgctgccagcgatcaaaggaaatgtgaccaggaaggggagcac ggccaccggagagagaccagggcttccagcgaggggaaccaggagcggcggggccctgcg ggccgtcacaccaagaggaactcttcctgggatggccgggtgccggagagggaggaccgc agctccaagaagaggaagctcccgtag

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