Pteropus alecto (black flying fox): 102885962
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Entry
102885962 CDS
T02993
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale01521
EGFR tyrosine kinase inhibitor resistance
pale01522
Endocrine resistance
pale04010
MAPK signaling pathway
pale04014
Ras signaling pathway
pale04015
Rap1 signaling pathway
pale04066
HIF-1 signaling pathway
pale04068
FoxO signaling pathway
pale04081
Hormone signaling
pale04114
Oocyte meiosis
pale04140
Autophagy - animal
pale04144
Endocytosis
pale04150
mTOR signaling pathway
pale04151
PI3K-Akt signaling pathway
pale04152
AMPK signaling pathway
pale04211
Longevity regulating pathway
pale04213
Longevity regulating pathway - multiple species
pale04510
Focal adhesion
pale04520
Adherens junction
pale04550
Signaling pathways regulating pluripotency of stem cells
pale04730
Long-term depression
pale04913
Ovarian steroidogenesis
pale04914
Progesterone-mediated oocyte maturation
pale05200
Pathways in cancer
pale05202
Transcriptional misregulation in cancer
pale05205
Proteoglycans in cancer
pale05214
Glioma
pale05215
Prostate cancer
pale05218
Melanoma
pale05224
Breast cancer
pale05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102885962 (IGF1R)
04014 Ras signaling pathway
102885962 (IGF1R)
04015 Rap1 signaling pathway
102885962 (IGF1R)
04066 HIF-1 signaling pathway
102885962 (IGF1R)
04068 FoxO signaling pathway
102885962 (IGF1R)
04151 PI3K-Akt signaling pathway
102885962 (IGF1R)
04152 AMPK signaling pathway
102885962 (IGF1R)
04150 mTOR signaling pathway
102885962 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
102885962 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
102885962 (IGF1R)
04140 Autophagy - animal
102885962 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
102885962 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
102885962 (IGF1R)
04520 Adherens junction
102885962 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
102885962 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
102885962 (IGF1R)
04914 Progesterone-mediated oocyte maturation
102885962 (IGF1R)
09156 Nervous system
04730 Long-term depression
102885962 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
102885962 (IGF1R)
04213 Longevity regulating pathway - multiple species
102885962 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102885962 (IGF1R)
05202 Transcriptional misregulation in cancer
102885962 (IGF1R)
05205 Proteoglycans in cancer
102885962 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
102885962 (IGF1R)
05214 Glioma
102885962 (IGF1R)
05218 Melanoma
102885962 (IGF1R)
05215 Prostate cancer
102885962 (IGF1R)
05224 Breast cancer
102885962 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102885962 (IGF1R)
01522 Endocrine resistance
102885962 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pale01001
]
102885962 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
pale04090
]
102885962 (IGF1R)
Enzymes [BR:
pale01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102885962 (IGF1R)
Protein kinases [BR:
pale01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
102885962 (IGF1R)
CD molecules [BR:
pale04090
]
Proteins
102885962 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
102885962
NCBI-ProteinID:
XP_006924199
LinkDB
All DBs
Position
Unknown
AA seq
1372 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFCVALSLWPATGEICGPGIDIRNDYQQLRRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGAMEGKPLCEKTSINNEYNYRCWTTNQCQKTCPSACGKRACTEDHECCHPECLGGCS
APDDDAACVACRHYYFAGVCVPSCPPSTYRFEGWRCVDRDFCANIPNAESSDTEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDALHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPSNKDIEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKDKIPIRKYADGTFDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRK
VFENFLHNSIFVPRPERKRRDVAQVANTTMSSRSRNSTADAYNVTDLEELETEYPFYESR
VDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWE
SRPENSIFLKWPEPENPNGLILMYEIKYGSQLEDQRECVSRQEYRKYGGAKLNRLNPGNY
TARIQATSLSGNGSWTDPVFFYVQAKTTYENFMHLIIALPIAILLIVGGLVIMLYVFHRK
RNSNRLGNGVLYASVNPEYFSAADVYVPDEWEVARDKITMSRELGQGSFGMVYEGVAKGV
VKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFVLSPPVCHSSQVRLLGVVSQGQPT
LVIMELMTRGDLKSYLRSMRPEIENNLVLVPPSLSKMIQMAGEIADGMAYLNANKFVHRD
LAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDV
WSFGVVLWEIATLAEQPYQGFSNEQVLRFVMEGGLLDKPDNCPDIMFELMRMCWQYNPKM
RPSFLEIIGSIKDEMEPGFQEVSFYYSDENKPPDMEELDLEPENMESIPLDPSASSLSLP
LPDRHSGHRAENGPGPGMLVLRASFDDRQPYAHMNGGRKNERPLPLPQSSTC
NT seq
4119 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctgc
gtcgcgctctcgctgtggccggcgaccggagaaatctgcgggcccggcatcgacatccgc
aacgactaccagcagctgaggcgcctggagaactgcacggtgatcgagggttacctgcac
atcctgctcatctccaaggccgaggactatcggagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctcgagagcctcggcgacctcttc
ccgaacctcacggtcatccgcggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggacatcgggctttacaacctgcggaacattacccggggggcc
atcaggatcgagaaaaacgccgacctctgctacctgtccacggtggactggtccctgatc
ctggacgccgtctccaacaactacatcgtggggaacaagcccccaaaggagtgtggggac
ctgtgtccaggggcgatggaggggaagccgctgtgtgagaagaccagcatcaacaatgaa
tacaactaccgttgctggacgacaaaccagtgccagaaaacgtgcccgagcgcgtgcggg
aagcgggcgtgcacggaggaccacgagtgctgccaccccgagtgcctgggcggctgcagc
gcgcccgacgacgacgcggcctgcgtggcctgtcgccactactacttcgccggcgtgtgc
gtgcccagctgcccgcccagcacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgcgccaacatccccaacgccgagagcagcgacaccgagggcttcgtcatccacgac
ggcgagtgcatgcaggagtgcccctcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgcgaaggaccttgccccaaagtctgcgaggaagaaaagaaaacgaagacc
attgattcggttacttctgctcagatgctccaaggatgcaccatattcaagggcaatttg
ctcattaatattcgacgaggcaataacattgcctcggagctggagaacttcatggggctt
attgaggtggtgacgggctacgtgaagatccgtcattcccacgccttggtgtccttgtcc
ttcctgaaaaaccttcgccagatcttaggagaggagcagctggaggggaattactccttc
tacgtcctcgacaaccagaacctgcagcagctgtgggactgggaccaccggaacctcacc
atcaaggccgggaaaatgtacttcgccttcaaccccaaactctgtgtctccgaaatttac
cgcatggaggaggtgacggggaccaaagggcgccagagcaaaggggacataaacaccagg
aacaacggagagagagcctcctgtgagagcgacgccctgcacttcacctctaccacgacg
tggaagaaccgcatcatcatcacgtggcaccggtaccggccgccagactacagggacctc
atcagcttcaccgtctactacaaggaagcaccctttaaaaacgtaacggaatatgacggg
caggacgcctgcggctccaacagctggaacatggtggacgtggacctcccttccaataag
gacatcgagcccggcatcctactgcacgggctgaagccctggacgcagtacgccgtgtac
gtcaaggccgtgaccctgaccatggtggagaatgaccacatccgcggagccaagagcgaa
atcttgtacatccgcaccaacgcctcagttccttccatccccctggacgtcctgtccgcg
tccaattcctcttcccagctgatcgtgaagtggaacccgccctctctgcccaacggcaac
ctgagctactacatcgtgaggtggcagcgccagcctcaggacagctacctgtaccggcac
aattactgctccaaagacaaaatccccatcaggaagtatgccgatggcaccttcgacatc
gaggaggtgacagagaaccccaagacggaggtgtgcggtggggagaaggggccttgctgc
gcgtgccccaaaaccgaagccgagaagcaggcggagaaggaggaggccgagtaccgcaaa
gtcttcgagaacttcctgcacaattccatcttcgtgcccagacccgagcggaagcggaga
gatgtcgcacaggtggccaacaccaccatgtccagccgaagcaggaacagcacggcggac
gcctacaacgtcacagacctggaagagctggagacggaatatcctttctacgagagcaga
gtggacaacaaggagagaaccgtcatctccaacctgcggcccttcactctgtaccgcatc
gacatccacagctgcaaccacgaggcggagaagctgggctgcagcgcctccaacttcgtt
tttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgggag
tcgcggccggaaaactccatctttttaaagtggccggaacctgagaatcccaatggatta
attctaatgtatgaaataaaatacggatcacaactcgaggaccagcgggagtgcgtgtcc
aggcaggagtaccgaaagtacggaggcgccaagctgaaccggctcaacccgggcaactac
acggcccgcatccaggccacctctctgtccggaaatgggtcgtggacggaccctgtgttc
ttctacgtccaggccaaaacgacctatgaaaatttcatgcacctgatcatcgccctgccc
atcgccatcctgctcatagtgggggggctggtgataatgctgtatgtcttccaccggaaa
agaaacagcaacaggctggggaatggagtgctgtacgcgtccgtgaaccccgaatacttc
agcgcggctgacgtgtacgtgcccgacgagtgggaggtggcccgcgacaagatcaccatg
agccgggagctgggccagggctccttcgggatggtgtatgagggcgtggccaagggcgtg
gtcaaggacgagcccgaaaccagggtggccattaaaaccgtgaacgaggccgcgagcatg
cgcgagaggattgaatttctcaacgaggcttcggtgatgaaggagtttgttctgagtcct
cctgtctgccattcctcccaggtgcggctgctgggcgtggtgtcccagggccagccaacg
ctggtcatcatggaactgatgacacgaggcgatctcaagagttacctcaggtccatgagg
ccggagatcgagaataatctggtcctcgtgcctccaagcctgagcaagatgatccagatg
gcgggagagatcgcggacggcatggcgtacctgaacgccaacaagttcgtgcacagagat
ctggccgcccgcaactgcatggtggccgaggatttcaccgtcaaaatcggagatttcggt
atgaccagagacatctacgagacagactattaccggaagggagggaaaggcctgctgccc
gtgcgctggatgtcccctgagtccctgaaggacggcgtcttcaccactcattctgacgtc
tggtccttcggcgtcgtcctctgggagatcgccacgctggccgagcagccgtaccagggc
ttctccaacgagcaggtgctgcgcttcgtcatggagggcggcctgctggacaagccggac
aactgccccgacataatgttcgagctgatgcgcatgtgctggcagtacaaccccaagatg
cggccgtcgttcctggagatcatcggcagcatcaaggacgagatggagcccggcttccag
gaggtgtccttctactacagcgacgagaacaagccgcccgacatggaggagctggacctg
gagccggagaacatggagagcatcccgctggacccgtcggcctcgtcgctgtccctgccg
ctgcccgacagacactcgggacacagggccgagaacggcccgggcccgggcatgctggtc
ctccgggccagcttcgacgacaggcagccttacgcgcacatgaacgggggacgcaagaac
gagaggccgctgcctctgccccagtcgtccacctgctga
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integrated database retrieval system
