Pteropus alecto (black flying fox): 102886232 Help Entry 102886232         CDS       T02993                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism pale  Pteropus alecto (black flying fox) Pathway pale00230   Purine metabolism pale01100   Metabolic pathways pale01522   Endocrine resistance pale04015   Rap1 signaling pathway pale04020   Calcium signaling pathway pale04022   cGMP-PKG signaling pathway pale04024   cAMP signaling pathway pale04062   Chemokine signaling pathway pale04072   Phospholipase D signaling pathway pale04081   Hormone signaling pale04082   Neuroactive ligand signaling pale04114   Oocyte meiosis pale04211   Longevity regulating pathway pale04213   Longevity regulating pathway - multiple species pale04261   Adrenergic signaling in cardiomyocytes pale04270   Vascular smooth muscle contraction pale04371   Apelin signaling pathway pale04540   Gap junction pale04611   Platelet activation pale04713   Circadian entrainment pale04714   Thermogenesis pale04723   Retrograde endocannabinoid signaling pale04724   Glutamatergic synapse pale04725   Cholinergic synapse pale04727   GABAergic synapse pale04740   Olfactory transduction pale04750   Inflammatory mediator regulation of TRP channels pale04911   Insulin secretion pale04912   GnRH signaling pathway pale04913   Ovarian steroidogenesis pale04914   Progesterone-mediated oocyte maturation pale04915   Estrogen signaling pathway pale04916   Melanogenesis pale04918   Thyroid hormone synthesis pale04921   Oxytocin signaling pathway pale04923   Regulation of lipolysis in adipocytes pale04925   Aldosterone synthesis and secretion pale04926   Relaxin signaling pathway pale04927   Cortisol synthesis and secretion pale04928   Parathyroid hormone synthesis, secretion and action pale04934   Cushing syndrome pale04935   Growth hormone synthesis, secretion and action pale04962   Vasopressin-regulated water reabsorption pale04970   Salivary secretion pale04971   Gastric acid secretion pale04972   Pancreatic secretion pale04976   Bile secretion pale05032   Morphine addiction pale05163   Human cytomegalovirus infection pale05166   Human T-cell leukemia virus 1 infection pale05200   Pathways in cancer pale05207   Chemical carcinogenesis - receptor activation pale05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pale00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     102886232 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     102886232 (ADCY3)    04371 Apelin signaling pathway     102886232 (ADCY3)    04020 Calcium signaling pathway     102886232 (ADCY3)    04072 Phospholipase D signaling pathway     102886232 (ADCY3)    04024 cAMP signaling pathway     102886232 (ADCY3)    04022 cGMP-PKG signaling pathway     102886232 (ADCY3)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102886232 (ADCY3)    04081 Hormone signaling     102886232 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     102886232 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     102886232 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     102886232 (ADCY3)    04062 Chemokine signaling pathway     102886232 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     102886232 (ADCY3)    04923 Regulation of lipolysis in adipocytes     102886232 (ADCY3)    04912 GnRH signaling pathway     102886232 (ADCY3)    04913 Ovarian steroidogenesis     102886232 (ADCY3)    04915 Estrogen signaling pathway     102886232 (ADCY3)    04914 Progesterone-mediated oocyte maturation     102886232 (ADCY3)    04921 Oxytocin signaling pathway     102886232 (ADCY3)    04926 Relaxin signaling pathway     102886232 (ADCY3)    04935 Growth hormone synthesis, secretion and action     102886232 (ADCY3)    04918 Thyroid hormone synthesis     102886232 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     102886232 (ADCY3)    04916 Melanogenesis     102886232 (ADCY3)    04925 Aldosterone synthesis and secretion     102886232 (ADCY3)    04927 Cortisol synthesis and secretion     102886232 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102886232 (ADCY3)    04270 Vascular smooth muscle contraction     102886232 (ADCY3)   09154 Digestive system    04970 Salivary secretion     102886232 (ADCY3)    04971 Gastric acid secretion     102886232 (ADCY3)    04972 Pancreatic secretion     102886232 (ADCY3)    04976 Bile secretion     102886232 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     102886232 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     102886232 (ADCY3)    04727 GABAergic synapse     102886232 (ADCY3)    04725 Cholinergic synapse     102886232 (ADCY3)    04723 Retrograde endocannabinoid signaling     102886232 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     102886232 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     102886232 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     102886232 (ADCY3)    04213 Longevity regulating pathway - multiple species     102886232 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     102886232 (ADCY3)    04714 Thermogenesis     102886232 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102886232 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     102886232 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     102886232 (ADCY3)    05163 Human cytomegalovirus infection     102886232 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     102886232 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     102886232 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     102886232 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     102886232 (ADCY3) Enzymes [BR:pale01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      102886232 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA Motif Other DBs NCBI-GeneID:  102886232 NCBI-ProteinID:  XP_006910341 LinkDB All DBs Position Unknown AA seq 1145 aa AA seqDB search MPRNQGFSDPEYSAEYSAEYSVSLPSDPERGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSRDQLAPLVVAGIWLLLDII LFVLCKKGLLPDRVTRKVVPYLLWLLITAQIFSYLGLNFARAHAASDTVGWQAFFVFSFF ITLPLSLSPIVVISVVSCIVHTLVLGVTVAQQQQDGLKGMQLLREILASVSLYLCAIIVG ITSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGDGGSRCD YLDEKGIETYLIIASKPEVKKTAVQNGLNGSALPNGAPPSSQPSSPALIETKEPNGSVHA SGSTSEEPEEQGAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA QVVKKRNTFLLSMRFMEPEMETRYSVEKEKQSGAAFSCSCVVLLCAALGEMLVDPWLMTN YVTFVVGEVLLLILTICSLAAIFPQAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN VVDMLSCLQYYTGPSNGTAGMEMEDGCTENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM LLITGAVAVVNIYAWCPIFDEYDRRRFQEHNFPVVALEKMQILSTAGLNGTDRLPLLPSK YSMTAMIFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSNKEEKSDKERWQHLADLADF ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV MGNIQVVEDTQAILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKPATFPNGSSVTLPHQ VVDNS NT seq 3438 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctccgaccccgagtactcggcggagtactcggcggagtac tccgtcagcctgccctctgaccctgagcgcggggtgggccggacccatgaaatctctgtg cggaactcggggtcctgcctctgcctgcctcgctttatgcggctgactttcgtgcccgag tccttggagaacctgtaccagacctatttcaaaaggcagcgccatgagaccctgctggtg ctggtggtcttcgcagccctcttcgactgctacgtggtggtcatgtgcgctgtggtcttc tcccgcgaccagctggctcccctcgtggtggctgggatctggctgctgttggatatcatc ctcttcgtgctctgcaaaaaggggctgctcccggaccgggtcacccggaaagtggtgccc tatctcctgtggctgctgataacagcccagatcttctcctacttgggcctgaactttgcc cgcgcccatgcggccagcgacacagtgggctggcaggccttctttgtcttctccttcttc atcacgctgcccctcagcctcagccccatcgttgtcatctctgtggtctcctgtattgtg cacaccctcgtcttgggggtcaccgtggcccagcagcagcaggatggactgaaggggatg cagttgctgagagagatcctggccagtgtctccctgtacctttgcgccatcatcgtgggc atcacgtcctactacatggcagaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctt tccatcctgcccaagcacgtggccgacgagatgctcaaggacatgaagaaggacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccacgagaacgtcagcatc cttttcgcggacatcgtgggcttcacccagctgtcctctgcctgcagcgcacaggagctc gtgaagctgctcaacgagctctttgcccgttttgacaagctggcggccaaataccaccag ctgcggattaagatcctgggcgactgttactattgcatctgtggcctgcctgactaccga gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgagagaagacgaagaccggggtggacatgcgtgtgggggtgcacacaggcaccgtg ctggggggcgtcctgggccagaagcgctggcagtacgatgtttggtccactgatgtgact gtggccaacaagatggaggccggcggcatccccgggcgtgtgcacatctcacagagcacc ttggactgcctgaagggggagttcgacgtggagccgggcgacgggggcagccgctgcgac tacctggatgagaagggcatcgaaacctacctcatcatcgcatccaagccagaggtgaag aagacggccgtccaaaatggcctcaatggctcggccctgcccaatggagccccgccttcc tcgcagcccagctcccccgccctcatcgagaccaaggagcccaacgggagtgtccacgcc agcgggtccacgtcggaggagcccgaggagcaaggggcccaggctgacaacccctccttc cccaaccctcgccggaggctgcgcctccaggacctggccgacagagtggtagacgcctcc gaggacgagcatgagctcaaccagctgctcaacgaggccctgctcgagcgggagtccgcc caggtagtgaagaagagaaacaccttcctcctgtccatgcggttcatggagcccgagatg gagacgcgctactcagtggagaaggagaagcagagcggagctgccttcagctgctcctgc gtcgtcctgctctgtgcggccctgggcgagatgctcgtcgacccctggctaatgacaaac tatgtgacctttgtggttggggaggttctgcttctgatcctgacgatctgctcgctggct gccatctttccccaggcctttcctaagaagctcgtggccttctcaacctggatcgaccgg acccgctgggccaggaacacctgggccatgttagccatcttcattctggttatggcaaat gtcgtggacatgcttagctgcctccagtactacacgggacccagcaacggcaccgcaggg atggagatggaggatggctgcacggagaaccccaagtattacaactatgtcgccgtgctg tcactcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacgctcatg ctgctcatcactggcgccgtagccgtcgtcaacatctatgcctggtgccccatcttcgat gaatatgaccgcagacgtttccaggaacacaactttcctgtggttgccttggagaagatg cagatactctccaccgctgggctcaatggcactgacaggctgcccctgctgccctccaag tactcgatgacagcgatgatcttcgtcatgatgctgagcttttactacttctcccgccac gtggaaaaactggctcggacactgttcttatggaagattgaggtccatgaccagaaggaa cgtgtctatgagatgcgacgctggaatgaggccttggtcaccaacatgttgcccgagcac gtggcacgccatttcctggggtccaagaagagagatgaggaactgtacagccagtcttat gatgagattggagtcatgtttgcctccctgcccaacttcgctgacttctacacagaggag agcatcaataatggtggcattgagtgtctgcgctttctcaacgagatcatctcagatttt gactctctcctggacaatcccaaattccgggtcatcaccaagatcaaaaccattggcagt acctatatggcagcttcaggagtcaccccagatgtcaacaccaatggctttaccagctcc aacaaggaggagaagtcagacaaggagcgctggcagcacctggctgatctggctgacttc gcactagccatgaaggatacgcttaccaacatcaacaaccagtccttcaacaacttcatg ctgcgcataggcatgaacaaaggaggggtactggctggggtcattggagcccggaaacca cactatgacatctggggcaacacagtcaacgttgccagcaggatggagtccacgggggtc atgggcaacattcaggtggtagaagacacacaggccatcctccgagagtacggcttccgc ttcgtgaggcgagggcccatctttgtgaaagggaaaggggagctgctaacctttttcttg aaaggccgtgacaagccagccaccttccctaacggctcctctgtcacactgccccaccag gtggtagacaactcctga

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