Pteropus alecto (black flying fox): 102887078 Help Entry 102887078         CDS       T02993                                  Symbol PRKCA Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism pale  Pteropus alecto (black flying fox) Pathway pale01521   EGFR tyrosine kinase inhibitor resistance pale04010   MAPK signaling pathway pale04012   ErbB signaling pathway pale04014   Ras signaling pathway pale04015   Rap1 signaling pathway pale04020   Calcium signaling pathway pale04066   HIF-1 signaling pathway pale04070   Phosphatidylinositol signaling system pale04071   Sphingolipid signaling pathway pale04072   Phospholipase D signaling pathway pale04082   Neuroactive ligand signaling pale04150   mTOR signaling pathway pale04151   PI3K-Akt signaling pathway pale04261   Adrenergic signaling in cardiomyocytes pale04270   Vascular smooth muscle contraction pale04310   Wnt signaling pathway pale04360   Axon guidance pale04370   VEGF signaling pathway pale04510   Focal adhesion pale04540   Gap junction pale04613   Neutrophil extracellular trap formation pale04650   Natural killer cell mediated cytotoxicity pale04664   Fc epsilon RI signaling pathway pale04666   Fc gamma R-mediated phagocytosis pale04670   Leukocyte transendothelial migration pale04713   Circadian entrainment pale04720   Long-term potentiation pale04723   Retrograde endocannabinoid signaling pale04724   Glutamatergic synapse pale04725   Cholinergic synapse pale04726   Serotonergic synapse pale04727   GABAergic synapse pale04728   Dopaminergic synapse pale04730   Long-term depression pale04750   Inflammatory mediator regulation of TRP channels pale04911   Insulin secretion pale04912   GnRH signaling pathway pale04916   Melanogenesis pale04918   Thyroid hormone synthesis pale04919   Thyroid hormone signaling pathway pale04921   Oxytocin signaling pathway pale04925   Aldosterone synthesis and secretion pale04926   Relaxin signaling pathway pale04928   Parathyroid hormone synthesis, secretion and action pale04929   GnRH secretion pale04933   AGE-RAGE signaling pathway in diabetic complications pale04935   Growth hormone synthesis, secretion and action pale04960   Aldosterone-regulated sodium reabsorption pale04961   Endocrine and other factor-regulated calcium reabsorption pale04970   Salivary secretion pale04971   Gastric acid secretion pale04972   Pancreatic secretion pale05017   Spinocerebellar ataxia pale05022   Pathways of neurodegeneration - multiple diseases pale05031   Amphetamine addiction pale05032   Morphine addiction pale05143   African trypanosomiasis pale05146   Amoebiasis pale05161   Hepatitis B pale05163   Human cytomegalovirus infection pale05164   Influenza A pale05170   Human immunodeficiency virus 1 infection pale05171   Coronavirus disease - COVID-19 pale05200   Pathways in cancer pale05205   Proteoglycans in cancer pale05206   MicroRNAs in cancer pale05207   Chemical carcinogenesis - receptor activation pale05214   Glioma pale05223   Non-small cell lung cancer pale05225   Hepatocellular carcinoma pale05231   Choline metabolism in cancer pale05415   Diabetic cardiomyopathy pale05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pale00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     102887078 (PRKCA)    04012 ErbB signaling pathway     102887078 (PRKCA)    04014 Ras signaling pathway     102887078 (PRKCA)    04015 Rap1 signaling pathway     102887078 (PRKCA)    04310 Wnt signaling pathway     102887078 (PRKCA)    04370 VEGF signaling pathway     102887078 (PRKCA)    04066 HIF-1 signaling pathway     102887078 (PRKCA)    04020 Calcium signaling pathway     102887078 (PRKCA)    04070 Phosphatidylinositol signaling system     102887078 (PRKCA)    04072 Phospholipase D signaling pathway     102887078 (PRKCA)    04071 Sphingolipid signaling pathway     102887078 (PRKCA)    04151 PI3K-Akt signaling pathway     102887078 (PRKCA)    04150 mTOR signaling pathway     102887078 (PRKCA)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     102887078 (PRKCA)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     102887078 (PRKCA)    04540 Gap junction     102887078 (PRKCA)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     102887078 (PRKCA)    04650 Natural killer cell mediated cytotoxicity     102887078 (PRKCA)    04664 Fc epsilon RI signaling pathway     102887078 (PRKCA)    04666 Fc gamma R-mediated phagocytosis     102887078 (PRKCA)    04670 Leukocyte transendothelial migration     102887078 (PRKCA)   09152 Endocrine system    04911 Insulin secretion     102887078 (PRKCA)    04929 GnRH secretion     102887078 (PRKCA)    04912 GnRH signaling pathway     102887078 (PRKCA)    04921 Oxytocin signaling pathway     102887078 (PRKCA)    04926 Relaxin signaling pathway     102887078 (PRKCA)    04935 Growth hormone synthesis, secretion and action     102887078 (PRKCA)    04918 Thyroid hormone synthesis     102887078 (PRKCA)    04919 Thyroid hormone signaling pathway     102887078 (PRKCA)    04928 Parathyroid hormone synthesis, secretion and action     102887078 (PRKCA)    04916 Melanogenesis     102887078 (PRKCA)    04925 Aldosterone synthesis and secretion     102887078 (PRKCA)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     102887078 (PRKCA)    04270 Vascular smooth muscle contraction     102887078 (PRKCA)   09154 Digestive system    04970 Salivary secretion     102887078 (PRKCA)    04971 Gastric acid secretion     102887078 (PRKCA)    04972 Pancreatic secretion     102887078 (PRKCA)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     102887078 (PRKCA)    04961 Endocrine and other factor-regulated calcium reabsorption     102887078 (PRKCA)   09156 Nervous system    04724 Glutamatergic synapse     102887078 (PRKCA)    04727 GABAergic synapse     102887078 (PRKCA)    04725 Cholinergic synapse     102887078 (PRKCA)    04728 Dopaminergic synapse     102887078 (PRKCA)    04726 Serotonergic synapse     102887078 (PRKCA)    04720 Long-term potentiation     102887078 (PRKCA)    04730 Long-term depression     102887078 (PRKCA)    04723 Retrograde endocannabinoid signaling     102887078 (PRKCA)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     102887078 (PRKCA)   09158 Development and regeneration    04360 Axon guidance     102887078 (PRKCA)   09159 Environmental adaptation    04713 Circadian entrainment     102887078 (PRKCA)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     102887078 (PRKCA)    05206 MicroRNAs in cancer     102887078 (PRKCA)    05205 Proteoglycans in cancer     102887078 (PRKCA)    05207 Chemical carcinogenesis - receptor activation     102887078 (PRKCA)    05231 Choline metabolism in cancer     102887078 (PRKCA)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     102887078 (PRKCA)    05214 Glioma     102887078 (PRKCA)    05223 Non-small cell lung cancer     102887078 (PRKCA)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     102887078 (PRKCA)    05161 Hepatitis B     102887078 (PRKCA)    05171 Coronavirus disease - COVID-19     102887078 (PRKCA)    05164 Influenza A     102887078 (PRKCA)    05163 Human cytomegalovirus infection     102887078 (PRKCA)   09174 Infectious disease: parasitic    05146 Amoebiasis     102887078 (PRKCA)    05143 African trypanosomiasis     102887078 (PRKCA)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     102887078 (PRKCA)    05022 Pathways of neurodegeneration - multiple diseases     102887078 (PRKCA)   09165 Substance dependence    05031 Amphetamine addiction     102887078 (PRKCA)    05032 Morphine addiction     102887078 (PRKCA)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     102887078 (PRKCA)    05415 Diabetic cardiomyopathy     102887078 (PRKCA)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     102887078 (PRKCA)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     102887078 (PRKCA)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pale01001]     102887078 (PRKCA)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:pale04131]     102887078 (PRKCA) Enzymes [BR:pale01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      102887078 (PRKCA) Protein kinases [BR:pale01001]  Serine/threonine kinases: AGC group   PKC family [OT]    102887078 (PRKCA) Membrane trafficking [BR:pale04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     102887078 (PRKCA) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C C1_2 ABC1 Kinase-like Motif Other DBs NCBI-GeneID:  102887078 NCBI-ProteinID:  XP_015445192 LinkDB All DBs Position Unknown AA seq 672 aa AA seqDB search MADVFPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNAE LRQKFEKAKLGPAGNKVISPSEDRRQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMEGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDG EDEDELFQSIMEHNVSYPKSLSKEAVSICKGLMTKHPGKRLGCGPEGERDVREHAFFRRI DWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVN PQFVHPILQSAV NT seq 2019 nt NT seq  +upstreamnt  +downstreamnt atggctgacgttttcccggccaacgattccacagcgtctcaggacgtggccaaccgcttc gcgcgcaaaggggcgctgagacagaagaacgtgcatgaggtgaaggaccacaaattcatc gcccggttcttcaagcagcccaccttctgcagccactgcaccgacttcatctgggggttt gggaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgaa tttgttacattttcctgtccgggtgcggataagggacccgacactgatgaccccaggagc aagcacaagtttaaaatccacacttacggaagccccaccttctgtgatcactgtgggtca ctgctgtacggacttatccatcaagggatgaaatgtgacacctgcgacatgaatgtgcac aagcagtgtgtgataaacgtccctagcctctgtgggatggaccacacagagaagaggggg cggatctacctgaaggctgaggtcaccgacgaaaagctccatgtcacagtacgagatgca aaaaatctcatccctatggatccaaatggactttcagacccttacgtgaagctgaaactt attcctgatcccaagaatgaaagcaaacaaaaaaccaaaaccatccgctccacactgaac cctcagtggaatgagtcgtttaccttcaaattaaaaccttcggataaagaccgacgactg tccgtagaaatctgggactgggatcgaacaacaaggaacgacttcatgggctccctttcc ttcggcgtttcggagttgatgaagatgccggccagtggatggtacaagttgcttaaccaa gaagaaggtgagtactacaacgtgcccattccagaaggagatgaggaaggaaacgcggag ctccggcagaaattcgagaaagccaagcttggccctgctggtaacaaagtaatcagtcct tcagaagacaggagacaaccttccaacaaccttgacagggtgaaactcaccgacttcaat ttcctcatggtcctggggaaggggagttttggaaaggtgatgctggccgacaggaagggt acggaagaactgtacgctatcaaaatcctgaagaaggacgtggtgatccaggacgacgac gtggaatgcaccatggtagagaagcgcgtgctggctttgcttgacaagccgccgttcctg acacagctgcactcctgcttccagacggtggatcggctctacttcgtcatggaatacgtc aacggcggggacctcatgtaccacatccagcaagtaggaaaatttaaggaaccccaagca gtattctatgcagcagagatttccattggattgttctttcttcataaacgaggaatcatt tatagggatctgaagctagataacgtcatgctggattcagagggacacatcaagattgcc gactttgggatgtgcaaggaacacatgatggagggagtcacgaccaggaccttctgtggg accccagattacatcgccccggagataatcgcttatcagccgtacgggaaatctgtggac tggtgggcctacggcgtcctgttatatgaaatgctggccgggcagcccccattcgacggt gaagatgaagacgagttgtttcagtctataatggagcacaacgtttcttatccgaaatct ctatccaaggaggccgtttccatctgcaaaggactgatgaccaaacatcccggcaagcgt ctgggctgcgggcccgagggggaacgggacgtgcgagaacacgccttcttccggaggatc gactgggagaaactggaaaacagggagatccagccgccattcaagcccaaagtgtgcggc aaaggagcagaaaactttgacaagttcttcacacgagggcagcctgtcttaacgcctccc gaccagctggtcattgctaacatagaccagtctgatttcgaagggttctcgtacgtcaac ccccagttcgtgcaccccatcttacagagcgcagtatga

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