Pteropus alecto (black flying fox): 102895629
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Entry
102895629 CDS
T02993
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
pale
Pteropus alecto (black flying fox)
Pathway
pale04217
Necroptosis
pale04380
Osteoclast differentiation
pale04620
Toll-like receptor signaling pathway
pale04621
NOD-like receptor signaling pathway
pale04630
JAK-STAT signaling pathway
pale04658
Th1 and Th2 cell differentiation
pale04659
Th17 cell differentiation
pale05145
Toxoplasmosis
pale05160
Hepatitis C
pale05161
Hepatitis B
pale05162
Measles
pale05164
Influenza A
pale05165
Human papillomavirus infection
pale05167
Kaposi sarcoma-associated herpesvirus infection
pale05168
Herpes simplex virus 1 infection
pale05169
Epstein-Barr virus infection
pale05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
pale00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
102895629 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
102895629 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
102895629 (TYK2)
04621 NOD-like receptor signaling pathway
102895629 (TYK2)
04658 Th1 and Th2 cell differentiation
102895629 (TYK2)
04659 Th17 cell differentiation
102895629 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
102895629 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
102895629 (TYK2)
05160 Hepatitis C
102895629 (TYK2)
05171 Coronavirus disease - COVID-19
102895629 (TYK2)
05164 Influenza A
102895629 (TYK2)
05162 Measles
102895629 (TYK2)
05168 Herpes simplex virus 1 infection
102895629 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
102895629 (TYK2)
05169 Epstein-Barr virus infection
102895629 (TYK2)
05165 Human papillomavirus infection
102895629 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
102895629 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pale01001
]
102895629 (TYK2)
Enzymes [BR:
pale01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
102895629 (TYK2)
Protein kinases [BR:
pale01001
]
Non-receptor tyrosine kinases
JAK family [OT]
102895629 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
FERM_C_FAK1
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
102895629
NCBI-ProteinID:
XP_015453872
LinkDB
All DBs
Position
Unknown
AA seq
1183 aa
AA seq
DB search
MPLYHWGATARGSRPDGDGTQLTATRGGLKVFLHWAGPDGGEPWVTFSEATLTAEDVCMH
IAHKVGITPPCFSLFALFDAQAQVWLPPNHILEVSRDTSLTLHFRMRFYFRNWHGTNPQE
PAVYRCRPPGAKASSEQAEQGMRLLDPASFEYLFEQGKHEFVNDVASLWDLSNEEEIHHF
KNESLGMAFLHLCHLAVCLGVPLKKVARKISFKDCIPRSFRQQIQQHNAFTQLRLWIIFH
KFLWAFQPGHLSQQVIMVKYLATLERLAPRFGSECVPVCHLELLAQAKGKPCYVEDSSQA
PPDPGPESAPGPPTHEVLVTGTGGIRWRPAPAEGPSGGDGGRRRNPHAGSSGKKIKAQES
VTQPVDRLQEAPWTYFCDFQDITHVVLRECHVSIHCQDKCLKLTLPSRAMALSLVSLVDG
YFRLTADSNHYLCHEVAPPRLVMSIQDGVHGPLLEPFVLAKLRPEDGLYLIHWSTSHFNR
LILTVAQKDQAPGGQCLRLRKFPIELHAGTFTLESWDRSFPSVRELRAALQGYLLRAGDD
CFSLRHCCLPQPGEISNLIIRWGPEASTKPLSLSQLSFHRVCQDDITQLSHLGQGTRTNV
YEGLLRVGDRGPEEDKADGGDSPTAGRGHGQELRVVLKVLDPSHHGIALAFYETASLMSQ
VSHMHLAFVHGVCVHGSKNIMVAEYVEHGPLDVWLRRERGCVPVAWKVVVAQQLASALSY
LEDKSLVHGNVCGRNILLARPGLAEGTSPFIKLSDPGVGLGALSREERVERIPWLPPECL
SGGANSLSTAADKWGFGATLLEICFNGEAPLQGRSPSEKEHFYQKQYQLPEPSCLELAML
TSQCLTYEPAQRPSFRTILRDLTRLQPQNLVDGLAVTPDCQASDPTVFHKRYLKKIRDLG
EGHFGKVSLYCYDPTNDSTGEMVAVKALKAGCGPQLSTGWRREIDILRTLSHENIVKYKG
CCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHTQHYIHRDL
AARNVLLDNNRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKECKFYYASDV
WSFGVTMYELLTYCDSSQSPPSKFIELIGFTQGQMTVLRLTELLERGERLPRPEKCPCEI
YLLMKKCWKAEASFRPTFQNLIPILKTAHEKYQGQAPSVFSVC
NT seq
3552 nt
NT seq
+upstream
nt +downstream
nt
atgcctttgtaccactggggggccacagccaggggcagcaggcctgatggggacggaacc
cagctcacggctaccagaggaggcctgaaggtattcctgcactgggctggccccgatggt
ggagagccctgggtcaccttcagcgaggccacactgactgcagaggacgtctgcatgcac
attgcacacaaagtcggcatcactccaccctgcttcagtctctttgccctcttcgatgcc
caggcccaggtctggctgcccccaaaccacattctagaggtctccagagatacaagcctg
acgctgcacttccgcatgagattttatttccggaactggcatggcacaaatcctcaggag
ccagctgtgtaccgctgcaggcccccaggggccaaggcttcatcagaacaggcagagcag
ggcatgcgactcctggacccagcctcctttgagtacctctttgagcagggcaagcatgag
tttgtgaatgacgtagcatcgctgtgggacctgtcgaacgaggaggagatccaccacttt
aagaatgagagcctgggcatggcctttctgcacctctgccacctcgctgtctgccttggt
gttcccctaaagaaggtggccagaaagatcagcttcaaagactgcatcccgcgctccttc
cggcaacagatccagcaacacaacgcgttcacacaactgcgcctgtggatcatcttccac
aagttcctgtgggccttccagccaggccacctctcccaacaggtcatcatggtcaagtac
ctggccacactcgagcggctggcgccccgctttggctcggagtgcgtgcctgtgtgccac
ctagagctgttggcccaggccaaggggaagccgtgctacgtcgaggatagcagtcaggcc
cctccggaccctgggcccgagtctgctccaggaccccctacccatgaggtgctggtgact
ggcactggtggcatccggtggcggccagcaccggcagagggtcccagtggtggtgatggt
ggcaggagaaggaatccccatgccggctcatctgggaagaaaatcaaggcccaagagtca
gtcacccaacctgtggacaggctgcaggaggcgccatggacctacttctgtgacttccag
gacatcacccacgtagtactgagagaatgccatgtcagtatccactgtcaggacaagtgc
ttgaagctgactctgccttcccgggccatggccctgtccttggtatcactggtggatggc
tatttccgcctgacggccgactcaaaccactacctatgccatgaagtggctcctccacgg
ctggtgatgagtatccaggatggtgtccacggacccctgctggagccattcgtgctggcc
aagctgcgaccagaggatggcctctatctcatccactggagcaccagccacttcaaccgc
ctcatccttacggtggcccagaaagaccaggcacctggcggacagtgcttgcgcctgcgg
aagttccccattgagctgcatgcagggacctttacgctggagagctgggacaggtccttc
cccagtgtgcgtgagcttcgggctgccctgcagggctacttgctgcgggccggtgatgac
tgcttctccctgcgccactgctgcctgccacagccaggagagatctccaacctcatcatc
aggtgggggcctgaggccagcaccaagcctctcagcctcagccagctcagcttccaccgg
gtctgccaggatgacatcacccagctgtcccacttaggccagggcacaaggaccaatgtg
tatgagggcctcctgagagtgggtgacagaggacctgaggaagacaaggcagatggtggg
gattcccccacagcaggcaggggccatgggcaggagctgcgagtggtgctgaaggtgctg
gaccccagccaccatggcatcgccctggccttctacgagacagccagcctcatgagccag
gtatcccacatgcacctggccttcgtccatggcgtctgcgtgcatggctccaagaacatc
atggtggcagagtacgtggaacatggacccctagatgtgtggctgcggcgggagaggggc
tgcgtccctgtggcctggaaggtggtggtggcccagcagctggccagtgccctcagttac
ctggaagacaagagcctggtgcacggtaatgtgtgtggccggaacatcctgctggcacgt
ccagggttggcggagggcaccagcccattcatcaagctgagcgaccccggcgtgggcctg
ggtgccctctccagggaggaacgggtagagcggatcccctggctgcccccggagtgcctg
tctggtggggccaacagcctcagcacagcagctgacaagtggggttttggcgccaccctc
ctggagatctgcttcaacggggaggctcccctgcaaggccgcagcccctccgagaaagag
cacttctaccagaagcagtaccagctgcctgaaccctcgtgcctggagctggccatgctt
accagccagtgcctgacctatgagccagcccaacggccgtccttccgcaccatcctgcgt
gacctcactcggctgcagcctcaaaatcttgttgatggcttggctgtgactccagactgt
caggcgtcagaccccactgttttccacaagcgctatttgaaaaagatccgggatctgggc
gagggtcactttggcaaggtcagcctgtactgctacgacccgaccaatgacagcactggc
gagatggtggccgtgaaggcccttaaggcgggctgcggcccccagctcagcaccggctgg
aggcgggagatcgacatcctgcgcacgctctctcacgagaacatcgtcaaatacaagggg
tgctgcgaggaccaaggcgagaaatcagtgcagctcgtcatggagtacgtgcccctgggc
agcctccgagactacctgccccggcacagcgttggcctggcccagctgctgctgtttgct
cagcagatctgcgagggcatggcctacctgcacacgcagcactacatccaccgagacctg
gctgcgcgcaacgtgctgctggacaacaataggctggtcaagattggcgatttcggccta
gccaaagctgtgcctgaaggccacgagtactaccgcgtgcgagaggatggggacagtcct
gtgttctggtatgccccagagtgcttgaaggagtgtaagttctactatgcatccgacgtc
tggtcctttggggtcaccatgtatgaactgctgacctactgtgactccagccaaagcccc
ccttcgaaatttatcgagcttataggcttcacccaggggcagatgacagtactgaggctc
acagagctgctggagcgaggagagaggctgccgcggccagagaaatgtccctgtgagatc
tatctcctcatgaagaagtgctggaaggcagaggcctcattccgcccaaccttccagaac
ctcatacccatcctgaaaacagcccacgagaaataccagggccaggccccctcggtgttc
agtgtctgctga
DBGET
integrated database retrieval system
